In Brazil, meglumine antimoniate is the first drug of choice for mucosal leishmaniasis treatment followed by amphotericin B and pentamidine isethionate.
Benivaldo Ramos Ferreira Terceiro+8 more
doaj +1 more source
A preliminary serological study of Trypanosoma evansi and Trypanosoma lewisi in a Chinese human population [PDF]
Trypanosoma evansi, known as an animal trypanosome, is widely distributed in many countries of Africa, Asia and South America; it causes significant economic loss in these countries.
Courtois, Patrick+8 more
core +1 more source
The goal of this study was to evaluate inhaled pentamidine for the treatment of patients with mild and moderate Pneumocystis carinii pneumonitis. Eight adults with AIDS and pneumocystis pneumonia (4 with a first episode and 4 with a repeat pneumocystosis)
Adriana Weinberg+5 more
doaj +1 more source
The predominant mechanism of drug resistance in African trypanosomes is decreased drug uptake due to loss-of-function mutations in the genes for the transporters that mediate drug import. The role of transporters as determinants of drug susceptibility is
Fabrice E Graf+9 more
doaj +1 more source
Atypical human infections by animal trypanosomes: evaluation of human and animal trypanocidal drugs against Trypanosoma lewisi in Wistar rats [PDF]
Trypanosomosis is a disease of medical and veterinary importance, mainly distributed in tropical areas of Africa, Latin America and Asia. Some Trypanosoma species are typically pathogenic for animals, such as Trypanosoma vivax, T. congolense, T.
Chalermwong, Piangjai+4 more
core
AIDS-Related Extrapulmonary Pneumocystis carinii Infection Presenting as a Solitary Rectal Ulcer
Extrapulmonary infection with Pneumocystis carinii, although uncommon, is increasingly recognized. Use of aerosolized pentamidine versus a systemic medication is thought to be a contributing factor due to the low concentrations of drug that are incapable
Eric M Yoshida+4 more
doaj +1 more source
Structural Basis for S100B Interaction with its Target Proteins. [PDF]
The S100B protein is an intra- and extracellular signaling protein that plays a role in a multitude of cellular processes and abnormal S100B is associated with various neurological diseases and cancers.
Fan, L, Prez, KD
core
Low incidence of Pneumocystis carinii pneumonia in HIV patients receiving 300mg pentamidine aerosol every 2 weeks [PDF]
Bogner, Johannes R.+2 more
core +1 more source
Chronic pentamidine aerosol prophylaxis does not induce QT-prolongation and vetricular arrythmias [PDF]
Bogner, Johannes R.+2 more
core +1 more source
Once-Weekly Administration of Dapsone/Pyrimethamine vs. Aerosolized Pentamidine as Combined Prophylaxis for Pneumocystis carinii Pneumonia and Toxoplasmic Encephalitis in Human Immunodeficiency Virus-Infected Patients [PDF]
To evaluate combined prophylaxis for Pneumocystis carinii pneumonia (PCP) and toxoplasmic encephalitis, 533 patients with symptomatic human immunodeficiency virus infection and/or CD4 lymphocyte counts of
Heald, Alison+12 more
core