Managing antibody stability: Effects of stressors on Ipilimumab from the commercial formulation to diluted solutions [PDF]
The stability of the monoclonal antibody Ipilimumab, the active ingredient of Yervoy®, used for the treatment of different types of cancer, has been investigated.
Benedetta Fongaro +5 more
core +2 more sources
Abstract Radiographic examination has been an essential part of the diagnostic workflow in periodontology and implant dentistry. However, radiographic examination unavoidably involves ionizing radiation and its associated risks. Clinicians and researchers have invested considerable efforts in assessing the feasibility and capability of utilizing ...
Andy Wai Kan Yeung +5 more
wiley +1 more source
Soft Null Hypotheses: A Case Study of Image Enhancement Detection in Brain Lesions [PDF]
This work is motivated by a study of a population of multiple sclerosis (MS) patients using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) to identify active brain lesions.
Crainiceanu, Ciprian M. +4 more
core +2 more sources
Determination of the worst case for cleaning validation of equipment used in the radiopharmaceutical production of lyophilized reagents for 99mTc labeling [PDF]
Cleaning validation, a requirement of the current Good Manufacturing Practices (cGMP) for Drugs, consists of documented evidence that cleaning procedures are capable of removing residues to predetermined acceptance levels.
Luciana Valéria Ferrari Machado Porto +2 more
core +4 more sources
Poly (L-glutamic acid)-Paclitaxel Conjugates for Cancer Treatment [PDF]
Non
Shuang-Qing Zhang
core +2 more sources
Drug Repurposing for the Treatment of Bacterial and Fungal Infections [PDF]
Multidrug-resistant (MDR) pathogens pose a well-recognized global health threat that demands effective solutions; the situation is deemed a global priority by the World Health Organization and the European Centre for Disease Prevention and Control ...
Andrea Miró-Canturri +2 more
core +1 more source
Effect of fish bones and algae fibre as fertilisers for ryegrass [PDF]
In organic growing, both in Norway and elsewhere in Europe, significant amounts of fertiliser products not derived from certified organic farming are used, such as dried poultry manure or other types of fertilisers derived from conventional farms such as
Ahuja, Ishita, Løes, Anne-Kristin
core
Conformational Stability Effect of Polymeric Iron Chelators [PDF]
This work is licensed under a Creative Commons Attribution 4.0 International License.The design and synthesis of metal chelators with extraordinary metal affinities is a basic and challenging scientific problem of both fundamental and practical ...
Berkland, Cory, Qian, Jian
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Taking a Closer Look at the Disturbed Human Gut Microbiome: A Study of the Interplay between E. faecalis and variant E. coli Mutants. [PDF]
This research project aims to identify the interplay between various E. coli strains (isolated from mice) and E. faecalis both of which play crucial roles in the human gut microbiome. E.
Critchley, Tyra +1 more
core
Parenteral protein formulations: an overview of approved products within the European Union [PDF]
The study presented is a comprehensive overview of commercial parenteral protein formulations, approved by the European Medicines Agency (EMA), 1995-2018. The objective of this overview was to analyse current trends in the design of commercial parenteral
Crean, Abina M. +5 more
core +1 more source

