Structural characterization of the family GH115 alpha-glucuronidase from Amphibacillus xylanus yields insight into its coordinated action with alpha-arabinofuranosidases [PDF]
, 2021 The coordinated action of carbohydrate-active enzymes has mainly been evaluated for the purpose of complete saccharification of plant biomass (lignocellulose) to sugars. By contrast, the coordinated action of accessory hemicellulases on xylan debranching
Di Leo, Rosa +10 more
core +2 more sources
Can gadolinium contrast agents be replaced with saline for direct MR arthrography of the hip? A pilot study with arthroscopic comparison. [PDF]
, 2023 OBJECTIVE To compare image quality and diagnostic performance of preoperative direct hip magnetic resonance arthrography (MRA) performed with gadolinium contrast agent and saline solution.
Brunner, Alexander +7 more
core +1 more source
Exploiting cyanine dye J-aggregates/monomer equilibrium in hydrophobic protein pockets for efficient multi-step phototherapy: An innovative concept for smart nanotheranostics [PDF]
, 2021 After several decades of development in the field of near-infrared (NIR) dyes for photothermal therapy (PTT), indocyanine green (ICG) still remains the only FDA-approved NIR contrast agent. However, upon NIR light irradiation ICG can react with molecular
Alvarez Igarzabal, Cecilia Ines +7 more
core +1 more source
In vivo anticancer evaluation of the hyperthermic efficacy of anti-human epidermal growth factor receptor-targeted PEG-based nanocarrier containing magnetic nanoparticles [PDF]
, 2014 Polymeric nanoparticles with targeting moieties containing magnetic nanoparticles as theranostic agents have considerable potential for the treatment of cancer. Here we report the chemical synthesis and characterization of a poly(D,L-lactide-co-glycolide)
Claudia Innocenti +11 more
core +2 more sources
Combined use of UV and MS data for ICH Stability-Indication Method: Quantification and isoforms identification of intact nivolumab [PDF]
, 2022 Nivolumab (Opdivo®) is a fully human immunoglobulin G4 isotype approved for the treatment of many cancers. It acts as an immune checkpoint inhibitor by blocking the interaction between PD-1 (Programmed Cell Death Protein 1) – an inhibitory receptor ...
Cabeza, José +5 more
core +1 more source
The design and preclinical evaluation of a single-label bimodal nanobody tracer for image-guided surgery [PDF]
, 2021 Intraoperative guidance using targeted fluorescent tracers can potentially provide surgeons with real-time feedback on the presence of tumor tissue in resection margins.
Bridoux, J. +10 more
core +2 more sources
ChemPlusChem, Volume 89, Issue 12, December 2024.Antimony‐119 for radiopharmaceutical therapy: Antimony‐119 (119Sb, t1/2=38.19 h) is a promising candidate for radiopharmaceutical therapy using Auger electrons. Available literature on 119Sb is scarce, with only one successful case of chelation, and no reported in vivo applications.
Aivija Grundmane +2 more
wiley +1 more source
Prolonged consumption of energy drinks does not affect the processes of memory, and increases the activity of transaminases, and cholesterol concentration – animal model study results [PDF]
, 2016 Background . The consumption of energy drinks (ED) is popular among young people. There are concerns that it could be harmful for their health. Objectives.
Barbara Nieradko-Iwanicka +2 more
core +1 more source
Geochemistry, Geophysics, Geosystems, Volume 25, Issue 9, September 2024.Abstract Bamboo corals are promising archives of paleoceanographic conditions. Existing calibrations for element‐to‐calcium ratio (El/Ca) proxies of bamboo corals, however, are not necessarily calibrated to contemporaneous environmental parameters, thus weakening the reliability of the proxies. Here, we aim at calibrating the proxies by comparing El/Ca
Xiaoli Zhou +6 more
wiley +1 more source
The Mechanism of Low Levels of Nitrogen Dioxide Reaction With Unsaturated Fatty Acid Esters. [PDF]
, 1990 Nitrogen Dioxide is a toxic air pollutant that exists at less than 0.5 ppm in the atmosphere. This toxic compound is known to initiate autoxidation of unsaturated fatty acids both in vivo and in vitro.
Gallon, Aris Ann
core +2 more sources