Interactions of sodium pentobarbital with d-glucose and l-sorbose transport in human red cells [PDF]
Pentobarbital acts as a mixed inhibitor of net d-glucose exit, as monitored photometrically from human red cells. At 30°C the Ki of pentobarbital for inhibition of Vmax of zero-trans net glucose exit is 2.16±0.14 mM; the affinity of the external site of ...
Arain, M, Naftalin, R.J
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Ethanol Extract of the Flower Chrysanthemum morifolium Augments Pentobarbital-Induced Sleep Behaviors: Involvement of Cl− Channel Activation [PDF]
Dried Chrysanthemum morifolium flowers have traditionally been used in Korea for the treatment of insomnia. This study was performed to investigate whether the ethanol extract of Chrysanthemum morifolium flowers (EFC) enhances pentobarbital-induced sleep
Eun, Jae Soon+5 more
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The thermodynamics of general and local anesthesia [PDF]
General anesthetics are known to cause depression of the freezing point of transitions in biomembranes. This is a consequence of ideal mixing of the anesthetic drugs in the membrane fluid phase and exclusion from the solid phase.
Graesboll, Kaare+2 more
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Lavender oil-potent anxiolytic properties via modulating voltage dependent calcium channels [PDF]
Recent clinical data support the clinical use of oral lavender oil in patients suffering from subsyndromal anxiety. We identified the molecular mechanism of action that will alter the perception of lavender oil as a nonspecific ingredient of aromatherapy
Klugbauer, Norbert+5 more
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C-Jun N-terminal kinase 2 promotes liver injury via the mitochondrial permeability transition after hemorrhage and resuscitation [PDF]
Hemorrhagic shock leads to hepatic hypoperfusion and activation of mitogen-activated stress kinases (MAPK) like c-Jun N-terminal kinase (JNK) 1 and 2. Our aim was to determine whether mitochondrial dysfunction leading to hepatic necrosis and apoptosis ...
Czerny, Christoph+6 more
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Effect of pentobarbital anesthesia on ventricular defibrillation threshold in dogs [PDF]
The effect of pentobarbital anesthesia upon the minimal voltage and current required for electrical ventricular defibrillation (the defibrillation threshold) was investigated in dogs. Threshold current, energy, and charge in five dogs averaged 2 per cent,
Babbs, Charles F
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Effects of distention of the small intestine on the movements of the gallbladder and the sphincter of Oddi [PDF]
1. Dogs anesthetized with pentobarbital sodium were mainly used and effects of the distention of the small intestine on the movements of the gall bladder and the sphincter of Oddi were investigated. 2.
Nakayama, Sosogu
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Hemodiafiltration in Pentobarbital Poisoning
We report the use of continuous venovenous hemodiafiltration (CVVHD) in a case of massive intentional ingestion of pentobarbital associated with severe coma and hypotension. Despite a poor hemodynamic state, toxic epuration (15% of drug ingested) was obtained. However, death occurred 7 hr after the end of treatment.
Bironneau E+4 more
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Alterations in protein P53 expression during the development of pressure overload-induced left ventricular hypertrophy in rats [PDF]
The relation between myocardial structural and functional changes and p53 proteins during the development of left ventricular hypertrophy (LVH) has not yet been reported.
Stoyanova, V., Zhelev, Nikolai
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Pentobarbital-induced place aversion learning [PDF]
Pentobarbital is self-administered by rats, but has also been reported to produce a conditioned place aversion. Since the self-administration and place preference paradigms both are considered to assess drug reward, we further examined the hedonic ...
Lew, Gilbert
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