Results 1 to 10 of about 173,582 (269)

Sevoflurane, as opposed to pentobarbital anesthesia, attenuates LPS-induced myocardial injury by up-regulating TAF1D [PDF]

Scientific Reports
Septic cardiomyopathy (SCM) is a prevalent and severe complication associated with sepsis. This study explores the effects of sevoflurane and pentobarbital on lipopolysaccharide (LPS) -induced SCM and elucidates underlying mechanisms.
Zheng Liu, Qing Liu, Yujing Zhao, Junmei Xu, Yulong Cui   +4 more
doaj   +2 more sources

Unexpected epileptogenic effect of lethal doses of pentobarbital: a case report [PDF]

Journal of Neurocritical Care, 2023
Background Barbiturate poisoning is rare but potentially fatal. Case Report We reported a case of barbiturate poisoning in a 28-year-old woman who recovered from lethal pentobarbital deliberate self-poisoning.
Amélie Giudicelli-Bailly, Chiara Della Badia, Marc Augsburger, Hervé Quintard, Raphaël Giraud, Pia De Stefano   +5 more
doaj   +1 more source

Thermal Response of Laboratory Rats (Rattus norvegicus) during the Application of Six Methods of Euthanasia Assessed by Infrared Thermography

Animals, 2023
Refinement is one of the principles aiming to promote welfare in research animals. The techniques used during an experimental protocol, including euthanasia selection, must prevent and minimize suffering.
Adriana Domínguez-Oliva, Ismael Hernández-Ávalos, Adriana Olmos-Hernández, Juan Villegas-Juache, Antonio Verduzco-Mendoza, Daniel Mota-Rojas   +5 more
doaj   +1 more source

Case report: Fatal poisoning caused by additive effects of two barbiturates

Frontiers in Pharmacology, 2023
A case of fatal poisoning involving multiple psychotropic drugs is presented. Quantitative toxicological analysis showed femoral blood concentrations of pentobarbital, phenobarbital, duloxetine, acetaminophen and tramadol were 10.39, 22.57, 0.22, 0.61 ...
Sella Takei, Hiroshi Kinoshita, Mostofa Jamal, Mitsuru Kumihashi, Tadayoshi Yamashita, Etsuko Tanaka, Sachiko Kawahara, Hiroko Abe, Kunihiko Tsutsui, Shoji Kimura   +9 more
doaj   +1 more source

Correction for Inhibition Leads to an Allosteric Co-Agonist Model for Pentobarbital Modulation and Activation of α1β3γ2L GABAA Receptors. [PDF]

PLoS ONE, 2016
BACKGROUND:Pentobarbital, like propofol and etomidate, produces important general anesthetic effects through GABAA receptors. Photolabeling also indicates that pentobarbital binds to some of the same sites where propofol and etomidate act.
Alexis M Ziemba, Stuart A Forman
doaj   +1 more source

Defining a “Good Death”: Exploring Veterinarians’ Perceptions of Companion Animal Euthanasia

Animals, 2023
This study was designed to determine how veterinarians define a good euthanasia experience. This information is used to generate a working definition of companion animal euthanasia that aligns with animal welfare standards and pet owners’ expectations ...
Lori R. Kogan, Kathleen A. Cooney
doaj   +1 more source

Frontoparietal anodal tDCS reduces ketamine-induced oscillopathies

Translational Neuroscience, 2021
During the prodromal phase of schizophrenia with its complex and insidious clinical picture, electroencephalographic recordings detect widespread oscillation disturbances (or oscillopathies) during the wake–sleep cycle.
Lahogue Caroline, Pinault Didier
doaj   +1 more source

Development and Stability of a New Formulation of Pentobarbital Suppositories for Paediatric Procedural Sedation

Pharmaceutics, 2023
Pentobarbital is a drug of choice to limit motion in children during paediatric procedural sedations (PPSs). However, despite the rectal route being preferred for infants and children, no pentobarbital suppositories are marketed, and therefore they must ...
Matthieu Lebrat, Yassine Bouattour, Coralie Gaudet, Mouloud Yessaad, Mireille Jouannet, Mathieu Wasiak, Imen Dhifallah, Eric Beyssac, Ghislain Garrait, Philip Chennell, Valérie Sautou   +10 more
doaj   +1 more source

A Comparison of Epileptogenic Effect of Status Epilepticus Treated With Diazepam, Midazolam, and Pentobarbital in the Mouse Pilocarpine Model of Epilepsy

Frontiers in Neurology, 2022
Status epilepticus (SE) is a medical emergency associated with acute severe systemic damage and high mortality. Moreover, symptomatic SE is one of the highest risk factors for epileptogenesis.
Xiangzhen Tong, Zizhu Zhang, Jianping Zhu, Shuji Li, Shaogang Qu, Bing Qin, Yanwu Guo, Rongqing Chen, Rongqing Chen, Rongqing Chen   +9 more
doaj   +1 more source

Tanacetum parthenium enhances pentobarbital-induced sleeping behaviors [PDF]

Avicenna Journal of Phytomedicine, 2019
Objective: Sleep disorders are among the most common psychiatric and medical conditions. In the present study, the hypnotic effect of Tanacetum parthenium was studied in mice.  Material and Methods: The hydro-alcoholic extract (HAE) of T.
Fatemeh Forouzanfar, Hamed Ghazavi, Mohammad Mahdi Vahedi, Kimia Tarah, Zahra Yavari, Azar Hosseini, Azita Aghaee, Hasan Rakhshandeh   +7 more
doaj   +1 more source