Results 1 to 10 of about 165,562 (238)

Stability of Sodium Pentobarbital 5w/v% Aqueous Solution During Short‐Term Chilled and Ambient‐Temperature Storage [PDF]

open access: yesVeterinary Medicine and Science
The COVID‐19 pandemic made it difficult to obtain pharmaceutical‐grade injectable anaesthetics used in animal experiments in Japan. To address this problem, it is worth the effort to evaluate whether the use of non‐pharmaceutical‐grade sodium ...
Masakazu Dohi   +4 more
doaj   +2 more sources

Improvement of Impaired Memory in Mice by Taurine [PDF]

open access: yesNeural Plasticity, 2000
Taurine was extracted from Pegasus later-narius Cuvier to study its effects on learning and memory in mice. Mice were treated with different doses of taurine (10 mg/kg, 20 mg/kg, 40 mg/kg).
Bhupinder P. S. Vohra, Xiang Hui
doaj   +3 more sources

The effect of different immobilization approaches on red-eared sliders [PDF]

open access: yesScientific Reports
The ethical issues surrounding sacrifice methods in animal experimentation have garnered increasing attention, making immobilization and sedation an integral part of the sacrifice process for experimental animals.
Xin Niu   +7 more
doaj   +2 more sources

Potential of Pandanus odoratissimus as a CNS depressant in Swiss albino mice [PDF]

open access: yesBrazilian Journal of Pharmaceutical Sciences, 2011
In this study, several neuropharmacological effects of methanolic leaf extract of Pandanus odoratissimus (PO) (family; Pandanaceae) were studied in albino mice using various experimental models.
Sama Raju   +4 more
doaj   +4 more sources

Effects of Anesthesia with Pentobarbital/Ketamine on Mitochondrial Permeability Transition Pore Opening and Ischemic Brain Damage [PDF]

open access: yesBiomedicines
Background and Objective: The alteration of mitochondrial functions, especially the opening of the mitochondrial permeability transition pore (mPTP), has been proposed as a key mechanism in the development of lesions in cerebral ischemia, wherefore it is
Evelina Rekuviene   +3 more
doaj   +2 more sources

STUDIES OF PENTOBARBITAL DEPRESSION [PDF]

open access: bronzeAnesthesiology, 1954
Mark F. Wynn   +2 more
openaire   +4 more sources

Unexpected epileptogenic effect of lethal doses of pentobarbital: a case report [PDF]

open access: yesJournal of Neurocritical Care, 2023
Background Barbiturate poisoning is rare but potentially fatal. Case Report We reported a case of barbiturate poisoning in a 28-year-old woman who recovered from lethal pentobarbital deliberate self-poisoning.
Amélie Giudicelli-Bailly   +5 more
doaj   +1 more source

Thermal Response of Laboratory Rats (Rattus norvegicus) during the Application of Six Methods of Euthanasia Assessed by Infrared Thermography

open access: yesAnimals, 2023
Refinement is one of the principles aiming to promote welfare in research animals. The techniques used during an experimental protocol, including euthanasia selection, must prevent and minimize suffering.
Adriana Domínguez-Oliva   +5 more
doaj   +1 more source

A Comparison of Epileptogenic Effect of Status Epilepticus Treated With Diazepam, Midazolam, and Pentobarbital in the Mouse Pilocarpine Model of Epilepsy

open access: yesFrontiers in Neurology, 2022
Status epilepticus (SE) is a medical emergency associated with acute severe systemic damage and high mortality. Moreover, symptomatic SE is one of the highest risk factors for epileptogenesis.
Xiangzhen Tong   +9 more
doaj   +1 more source

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