Results 101 to 110 of about 52,401 (289)

Artesunate Inhibits Neointimal Hyperplasia by Promoting IRF4 Associated Macrophage Polarization

Advanced Science, EarlyView.
This study shows that macrophage interferon regulatory factor 4 (IRF4) improved arterial injury‐induced neointimal hyperplasia by promoting of M2 polarization via up‐regulating krüppel‐like factor 4 (KLF4) in rodent and nonhuman primate models. Notably, artesunate is identified as a potent inducer of IRF4 in macrophages, and proposed as a promising ...
Jinlin Miao, Yule Yong, Zhaohui Zheng, Kui Zhang, Wei Li, Jiayi Liu, Siyi Zhou, Juan‐juan Qin, Haoyang Sun, Yatao Wang, Xianghui Fu, Xing Luo, Siyu Chen, Zhi‐Gang She, Jingjing Cai, Ping Zhu   +15 more
wiley   +1 more source

Potential of Pandanus odoratissimus as a CNS depressant in Swiss albino mice

Brazilian Journal of Pharmaceutical Sciences, 2011
In this study, several neuropharmacological effects of methanolic leaf extract of Pandanus odoratissimus (PO) (family; Pandanaceae) were studied in albino mice using various experimental models.
Sama Raju, Narra Venkata Subbaiah, Kandukuri Sreeramulu Reddy, Amit Das, Krishnan Bala Murugan   +4 more
doaj   +1 more source

Oral Microalgae‐Based Biosystem to Enhance Irreversible Electroporation Immunotherapy in Hepatocellular Carcinoma

Advanced Science, Volume 12, Issue 15, April 17, 2025.
This study presents an innovative oral microalgae‐based biosystem to inhibit tumor growth, reduce PD‐1 expression, and activate immune responses of hepatocellular carcinoma. When combined with enhanced irreversible electroporation treatment, it demonstrates a synergistic effect that effectively reduces the tumor burden and enhances the tumor immune ...
Cheng Zeng, Shiyuan Hua, Jiayu Zhou, Tangye Zeng, Jianke Chen, Lijian Su, Angfeng Jiang, Min Zhou, Zhe Tang   +8 more
wiley   +1 more source

Characteristics of enzymatic induction provoked by chlordane [PDF]

The effects of various stresses, such as restraint and lowering or raising of environmental temperature, in mice pretreated with chlordane were investigated.
Denys, A., Guilbert-Ber, E., Levy, J.
core   +1 more source

Cell‐Type Specific Circuits in the Mammillary Body for Place and Object Recognition Memory

Advanced Science, Volume 12, Issue 13, April 3, 2025.
Li et al. defined two novel glutamatergic neuronal subtypes in the medial mammillary nucleus, pars lateralis‐located parvalbumin (PV) neurons, and basalis‐located Drd2 neurons. PV and Drd2 neurons differ in their electrophysiological properties encoded by Kcnn4 and Cacna1h, and selectively modulate place and object recognition memory by two distinct ...
Lanfang Li, Yiqing Guo, Wei Jing, Xiaomei Tang, Jinyu Zeng, Zhenye Hou, Yige Song, Aodi He, Hao Li, Ling‐Qiang Zhu, Youming Lu, Xinyan Li   +11 more
wiley   +1 more source

Yokukansan Enhances Pentobarbital-Induced Sleep in Socially Isolated Mice: Possible Involvement of GABAA – Benzodiazepine Receptor Complex

Journal of Pharmacological Sciences, 2011
.: In the present study, we investigated the effect of the Kampo medicine Yokukansan (YKS) on pentobarbital-induced sleep in group-housed and socially isolated mice. Socially isolated mice showed shorter sleeping time than the group-housed mice. YKS (300
Nobuaki Egashira, Ai Nogami, Katsunori Iwasaki, Ayumi Ishibashi, Naoki Uchida, Kotaro Takasaki, Kenichi Mishima, Ryoji Nishimura, Ryozo Oishi, Michihiro Fujiwara   +9 more
doaj  

Changes in pentobarbital induced sleeping-time in mice infected with Schistosoma mansoni and immunosuppressed Alterações no tempo de anestesia pelo pentobarbital sódico em camundongos infectados pelo Schistosoma mansoni e imunossuprimidos

Revista do Instituto de Medicina Tropical de São Paulo, 1995
To evaluate whether the intensity of the hepatic granulomatous response induced by S. mansoni eggs plays a role in drug metabolism, mice were infected with 40 cercariae and tested to assess the sodic pentobarbital induced sleeping-time.
Sônia Maria de Assis Fonseca Tonelli, Geraldo Brasileiro Filho, Eugênio Marcos de Andrade Goulart, Paulo Marcos Zech Coelho   +3 more
doaj   +1 more source

The Effect of Sodium Pentobarbital on the Toxicity of Certain Antihistamines [PDF]

, 1952
E. L. Way, Woodrow C. Herbert
openalex   +1 more source

Spectroscopic investigations of pentobarbital interaction with human serum albumin [PDF]

, 2010
The interaction between pentobarbital and human serum albumin has been investigated. The basic binding interaction was studied by UV-absorption and fluorescence spectroscopy.
Abu sharkh, Sawsan E., Abu Teir, Musa M., Abu-hadid, Mahmoud M., Darwish, Saqer M., Makharza, Sami A.   +4 more
core  

Muscle‐Derived Small Extracellular Vesicles Mediate Exercise‐Induced Cognitive Protection in Chronic Cerebral Hypoperfusion

Advanced Science, EarlyView.
sEVs have a critical role in orchestrating interorgan crosstalk and mediating exercise‐induced therapeutic effects. Lin et al. demonstrates that sEVs miR‐17/20a‐5p mediates the muscle‐brain crosstalk and emphasizes the central role of mTOR signaling in executing molecular programs that can protect brain health in response to exercise. Abstract Physical
Huawei Lin, Lianhua Yin, Weilin Liu, Rui Li, Tao Jiang, Minguang Yang, Yajun Cao, Sinuo Wang, Yan Yu, Cong Chen, Xiaoqin Guo, Wenju Wang, Huanhuan Liu, Yaling Dai, Jiamin Yan, Yanting Lin, Yanyi Ding, Chendong Ruan, Lei Yang, Tiecheng Wu, Jing Tao, Lidian Chen   +21 more
wiley   +1 more source