Results 191 to 200 of about 176,335 (333)

Development of an efficient mice model of cancer‐associated cardiac cachexia

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This work establishes a preclinical framework for targeting ubiquitin pathways to mitigate the morbidity of cancer‐related cardiopathy. Our integrated approach delineates a hierarchical progression from subcellular dysfunction to macroscopic cardiac deterioration. These findings mechanistically link tumor‐induced cachexia to cardiac dysfunction through
Shijie Xiong   +9 more
wiley   +1 more source

Studies on Drug Metabolism. V : Binding of Pentobarbital with Plasma Protein (1)

open access: bronze, 1968
Haruo Kitagawa   +3 more
openalex   +2 more sources

Intranasal Wharton's Jelly‐Derived Mesenchymal Stem Cell Therapy, Alone or in Conjunction With Therapeutic Hypothermia, Alleviates Neonatal Hypoxic‐Ischemic Brain Injury in Mice

open access: yesAnnals of Neurology, EarlyView.
This study demonstrates that intranasal Wharton's jelly‐derived mesenchymal stem cell (WJ‐MSC) administration at 3 or 10 days post‐insult reduced the lesion size and sensorimotor impairment following neonatal hypoxic‐ischemic (HI) brain injury in mice. WJ‐MSCs expressed receptors for HI‐upregulated chemokines and migrated from the nasal cavity into the
Caroline G. M. de Theije   +9 more
wiley   +1 more source

In Vitro Free Implantation of Stem Cells from Apical Papilla Using Injectable Hydrogel‐Laden 3D‐Printed Scaffold to Enhance Tissue Organization and Vascular Infiltration In Vivo

open access: yesAdvanced NanoBiomed Research, EarlyView.
This study explores CMCTS/oHA‐encapsulated high‐density stem cells from the apical papilla‐modified 3D‐printed PMMA composite scaffolds as a novel tissue engineering strategy. The hydrogel demonstrates excellent injectability and degradation, enhancing cell inoculation efficiency.
Ziqi Huang   +15 more
wiley   +1 more source

Sedative and hypnotic effects of nuciferine: enhancing rodent sleep via serotonergic system modulation. [PDF]

open access: yesInt J Neuropsychopharmacol
Wang LX   +13 more
europepmc   +1 more source

RNA m1A methyltransferase TRMT61A promotes colorectal tumorigenesis by enhancing ONECUT2 mRNA stability and is a potential therapeutic target

open access: yesCancer Communications, EarlyView.
Abstract Background The role of N1‐methyladenosine (m1A) in cancer is poorly understood. Here we explored the function of RNA methyltransferase TRNA methyltransferase 61A (TRMT61A) in colorectal cancer (CRC) and its potential as a therapeutic target. Methods RNA m1A levels were assessed through liquid chromatography‐mass spectrometry.
Xiaoting Zhang   +18 more
wiley   +1 more source

Exercise pre-conditioning prevents vascular toxicity caused by infusion of 5-fluorouracil in male rats. [PDF]

open access: yesAm J Cancer Res
Hammond ST   +6 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy