Results 191 to 200 of about 129,948 (248)

Safety, efficacy, pharmacokinetics, and mechanisms of novel 10B‐boronophenylalanine combined with a radio‐frequency quadrupole accelerator in boron neutron capture therapy: A preclinical study in head and neck squamous cell carcinoma

Precision Radiation Oncology, EarlyView.
This study demonstrates that the novel 10B‐BPA‐based BNCT system, combined with an RFQ accelerator, effectively targets head and neck squamous cell carcinoma. It induces tumor regression safely and efficiently by triggering DNA damage and activating the ROS/HIF‐1α/NF‐κB pathway, leading to caspase‐3‐mediated apoptosis.
Zhaoyuan Zhang, Junyan Li, Minhua Fan, Huafu Ouyang, Qiubo Chu, Huijie Yan, Yannan Zheng, Linxuan Huang, Gui Bao, Zhenting Ma, Shaobo Huang, Lin Li, Xiao Xu, Zhigang Liu   +13 more
wiley   +1 more source

Reconstruction of a segmental bone defect using vascularized tissue-engineered bone substitutes: An animal study. [PDF]

PLoS One
Wang Y, Lv Q, Zhang X, Liang J, Feng F, Li J, Cui Y.   +6 more
europepmc   +1 more source

Effect of ESWT on the microcirculation of the lower extremity in rats with diabetic vasculopathy: An experimental animal study. [PDF]

Turk J Phys Med Rehabil
Zhang J, Zhang B, He C.
europepmc   +1 more source

Gambogic acid-loaded transferrin-modified liposomes enhancing potent ferroptosis in breast cancer. [PDF]

Sci Rep
Rong W, Zhang M, Yang S, Wang K, Yang X, Zhang G, Li Z, Ding Y, Zhang T, Gai Y, Lan J.   +10 more
europepmc   +1 more source

Anesthesia blocks the cardiovascular response to baroreceptor unloading in rats. [PDF]

Function (Oxf)
Nieman ML, Sakthivel S, Mackenzie B, Lorenz JN.   +3 more
europepmc   +1 more source

Tetramethylpyrazine and renal ischemia-reperfusion injury: a systematic review and meta-analysis of preclinical studies. [PDF]

Front Pharmacol
Fu Z, Jiang L, Su X, Wang H, Li M.
europepmc   +1 more source

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Effects of pentobarbital and cocaine in rats expecting pentobarbital

Pharmacology Biochemistry and Behavior, 1982
Rats received extensive exposure to pentobarbital in a distinctive environment, and were subsequently tested for tolerance to the sedative effects of pentobarbital either in the distinctive environment or in an environment previously associated only with saline.
Riley E Hinson, Constantine X Poulos, Howard Cappell   +2 more
exaly   +3 more sources