Characterization of rhesus macaque model for cobalt-60 gamma-radiation source without use of blood product. [PDF]
Wise SY+8 more
europepmc +1 more source
Establishment and evaluation of a novel rat model of the fourth ventricle hemorrhage
In this study, a novel rat model of fourth ventricle hemorrhage was established via autologous blood injection through the foramen of Magendie. Anesthetized rats were positioned in a stereotaxic apparatus with their heads tilted downward at an angle of approximately 20° relative to the vertical axis.
Chuhua Fu+8 more
wiley +1 more source
Neuroprotective and intraocular pressure lowering effects of dual-functional memantine nitrate MN-08 on the experimental models of glaucoma. [PDF]
Hu H+8 more
europepmc +1 more source
Development of an efficient mice model of cancer‐associated cardiac cachexia
This work establishes a preclinical framework for targeting ubiquitin pathways to mitigate the morbidity of cancer‐related cardiopathy. Our integrated approach delineates a hierarchical progression from subcellular dysfunction to macroscopic cardiac deterioration. These findings mechanistically link tumor‐induced cachexia to cardiac dysfunction through
Shijie Xiong+9 more
wiley +1 more source
Corrigendum to "Quan M, Guo Q, Yan X, et al. Parkin deficiency aggravates inflammation-induced acute lung injury by promoting necroptosis in alveolar type II cells" [Chin Med J Pulm Crit Care Med 2024;2:265-278]. [PDF]
europepmc +1 more source
Improvement of sleep disorders through the adenosine A receptor agonist effect of <i>Phlomoides umbrosa</i> Turczaninow root extract in pentobarbital-induced ICR mice. [PDF]
Oh JH+13 more
europepmc +1 more source
This study revealed the antioxidant, anti‐inflammatory, and antidiabetic potentials of the seaweed Chaetomortpha aerea using in vitro, in vivo, and in silico approaches along with phytochemical analysis using gas chromatography–mass spectrometry. ADME/T analysis was also carried out to confirm drug likeness and toxicity prediction.
Md. Mahmudul Hasan+7 more
wiley +1 more source
How does the brain emerge from anesthesia and regain consciousness. [PDF]
Song X, Hu J.
europepmc +1 more source
This study demonstrates that intranasal Wharton's jelly‐derived mesenchymal stem cell (WJ‐MSC) administration at 3 or 10 days post‐insult reduced the lesion size and sensorimotor impairment following neonatal hypoxic‐ischemic (HI) brain injury in mice. WJ‐MSCs expressed receptors for HI‐upregulated chemokines and migrated from the nasal cavity into the
Caroline G. M. de Theije+9 more
wiley +1 more source