Results 71 to 80 of about 139,649 (278)
Advanced Science, EarlyView.A multifunctional regenerative composite is constructed by 3D‐printing thermosensitive PNIPAM hydrogel embedded with MPDA@IL‐10 nanoparticles and autologous BMSCs onto antigen‐depleted porcine bone matrix for beagle critical‐sized skull defect reconstruction.
Weihao Lv +16 more
wiley +1 more source
Advanced Science, EarlyView.TIPE1m NPs nanoparticles restore TIPE1 expression, promote RAB7A ubiquitination and degradation, suppress autophagic flux, and resensitize paclitaxel‐resistant triple‐negative breast cancer to therapy. ABSTRACT Acquired paclitaxel (PTX) resistance remains a major obstacle in triple‐negative breast cancer (TNBC) treatment.
Wei Hu +9 more
wiley +1 more source
Pentobarbital suppresses basal and reflexive pancreatic polypeptide release in dogs
, 1985 We sought to determine in overnight-fasted dogs whether basal or 2-deoxy-D-glucose (2-DG)-stimulated levels of pancreatic polypeptide (PP) could be reliably used as an index of cholinergic activity at the pancreas and thereby determine the effect of ...
T. L. Paquette +3 more
core +1 more source
Advanced Science, EarlyView.Magneto‐NIR‐II‐programmed NFSH nanozymes integrate magnetic blood–brain barrier (BBB) translocation, CD44 targeting, multimodal imaging, and cascade catalytic therapy for glioblastoma. Alternating magnetic fields and NIR‐II irradiation amplify ferroptosis, release H2S, suppress autophagic and mitophagic repair, and reshape the immune microenvironment ...
Ruocan Liu +7 more
wiley +1 more source
Pentobarbital intoxication as a potential underlying cause for electrocution in a bearded vulture
, 2023 Preliminary results were presented as an Abstract at the 24th Spanish Toxicology Congress, Córdoba, 9–11 November 2022.A bearded vulture (Gypaetus barbatus) found dead in northern Spain presented external lesions consistent with electrocution as the ...
I Sánchez-Barbudo +13 more
core +1 more source
Advanced Science, EarlyView.In human oral keratinocytes, OTUD6A promoted cell migration by deubiquitinating and stabilizing PRDX1. Conversely, OTUD6A deficiency reduced PRDX1 stability, triggering mitochondrial dysfunction and aggravating OU progression. ABSTRACT Oral ulcers (OU), as the most highly prevalent and recurrent oral mucosal lesion, have an unclear pathogenesis that ...
Xiaoyu Sun +15 more
wiley +1 more source
Improvement of Impaired Memory in Mice by Taurine
Neural Plasticity, 2000 Taurine was extracted from Pegasus later-narius Cuvier to study its effects on learning and memory in mice. Mice were treated with different doses of taurine (10 mg/kg, 20 mg/kg, 40 mg/kg).
Bhupinder P. S. Vohra, Xiang Hui
doaj +1 more source
Advanced Science, EarlyView.Tissue incision induces CXCL5 release, which activates neuronal CXCR2 on incision‐innervating sensory neurons. Neuronal CXCR2 couples with TRPA1 to drive mechanical pain and engages p38 MAPK signaling to upregulate TRPV1 and promote heat pain. Targeted Cxcr2 knockdown relieves incisional pain while preserving CXCR2‐dependent neutrophil responses ...
Yushuang Pan +10 more
wiley +1 more source
Hemodiafiltration in Pentobarbital Poisoning
Renal Failure, 1996 We report the use of continuous venovenous hemodiafiltration (CVVHD) in a case of massive intentional ingestion of pentobarbital associated with severe coma and hypotension. Despite a poor hemodynamic state, toxic epuration (15% of drug ingested) was obtained. However, death occurred 7 hr after the end of treatment.
E, Bironneau +4 more
openaire +2 more sources
Pentobarbital attenuates pulmonary vasoconstriction in isolated sheep lungs
, 1989 Pentobarbital sodium is a widely used anesthetic agent that has been demonstrated to attenuate systemic vascular responses to multiple pressors. To determine whether pentobarbital affected pulmonary vasoreactivity we determined the pulmonary vascular ...
R. C. Wetzel, L. D. Martin
core +1 more source