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Anesthesia in rabbits by intrahepatic sodium pentobarbital
Journal of Surgical Research, 1975Abstract A reliable method for anesthesia of laboratory rabbits by intrahepatic injection of sodium pentobarbital was developed. Anatomical dissection was the basis for designation of external landmarks for injection. The advantages of the method have been simplicity, accuracy of dosage based on body weight, and an induction speed great enough for ...
R, Jacobs, D L, Krohn
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Sodium Pentobarbital-Induced Mutations in the Hamster
Archives of Environmental Health: An International Journal, 1981When virgin Syrian hamsters aged 6 to 8 wk were mated during estrus and anesthetized with sodium pentobarbital (Nembutal) 4 to 5 hr before estimated ovulation, pregnancy wastage in the newly conceived litter was observed. This was manifested by polyspermy of moribund eggs and death of fertilized eggs, deficits of expected zygotes, and triploidy and ...
T, Ito, T H, Ingalls
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Prolonged Vertical Nystagmus After Pentobarbital Sodium Administration
American Journal of Ophthalmology, 1975Of 17 healthy adults without nystagmus who ingested 100 mg of pentobarbital sodium, six had up-beating, gaze-evoked vertical nystagmus 12 hours later. Three of them had nystgmus 36 hours later, but none of them had it 60 hours later. Therefore, one should be reluctant to ascribe this type of nystagmus to a disease of the central nervous system in ...
S, Lessell, P A, Wolf, D, Chronley
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Fate of sodium pentobarbital in rendered products
American Journal of Veterinary Research, 1985SUMMARY The fate of pentobarbital through rendering was evaluated by following a group of euthanatized animals through a commercial rendering facility. Samples of material were collected at various points in the rendering process, and assays for pentobarbital were conducted by an ultraviolet spectrophotometric method.
J J, O'Connor, C M, Stowe, R R, Robinson
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Hemodynamic effects of sodium pentobarbital in the bovine
Journal of Surgical Research, 1972Abstract The effects of intravenous sodium pentobarbital (SP) were studied in 34 normal and in 7 calves with brisket disease (BD). Average increase in pulmonary artery pressure was 12 mm Hg for normal calves with no significant change in BD calves. Average increase in femoral artery pressure after a transient decrease was 24 mm Hg in normal calves ...
F L, Anderson +3 more
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Effects of sodium pentobarbital on complex operant discriminations
Psychopharmacologia, 1964Results are reported for the effects of sodium pentobarbital on (a) zero delay matching-to-sample, (b) simultaneous oddity, and (c) variable delay matching-to-sample. In all these situations there are decrements in accuracy with increasing dose levels.
R, Berryman +3 more
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PENTOBARBITAL-SODIUM AND SCOPOLAMINE HYDROBROMIDE
Journal of the American Medical Association, 1936We began using pentobarbital-sodium and scopolamine hydrobromide for the relief of pain in labor at the Evanston Hospital in December 1932. Dr. Frederick C. Irving at the Boston Lying-in Hospital had been using these drugs for some time and with such satisfactory results that we were convinced of their superiority. One of us visited Dr.
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Modulation of conditioned taste aversion by sodium pentobarbital
Pharmacology Biochemistry and Behavior, 1980The effects of pentobarbital on the formation and expression of LiCl induced taste aversion were examined using a two-bottle preference test. Rats adapted to restricted fluid intake were offered a 15% sucrose solution 15 min after a pentobarbital or saline injection but prior to post-CS LiCl or control injections.
J T, Concannon, J, Freda
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Human cardiac sodium channels are affected by pentobarbital
European Journal of Anaesthesiology, 2001To investigate the response to general anaesthetics of different sodium channel subtypes, we examined the effects of pentobarbital, a close thiopental analogue, on single sodium channels from human ventricular muscle and compared them with existing data from human brain channels.Sodium channels from preparations of human ventricular muscle were ...
Wartenberg, H. C. +2 more
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