Results 201 to 210 of about 104,655 (257)

Pentobarbital sodium anesthesia in the dog

American Journal of Physiology, 1965
Studies have been done in the dog to determine some of the circulatory effects of anesthetic amounts of pentobarbital sodium. The results indicate that a) except for the initial transient hypotension that occurs on injection of the anesthetic, pentobarbital sodium has little influence on the mean arterial blood pressure of the normotensive dog; b ...
exaly   +3 more sources

Effects of sodium pentobarbital on thermoregulatory responses in the rat

Neuropharmacology, 1981
Abstract The effects of intraperitoneal and intraventricular administration of sodium pentobarbital on metabolic, respiratory and vasomotor activity, as well as body temperature of rats to different ambient temperatures ( T a ) of 8, 22 and 30°C, were assessed. Administration of sodium pentobarbital produced hpothermia in rats at both 8 and 22°C T
M T Lin
exaly   +3 more sources

Injectable sodium pentobarbital: Stability at room temperature

Journal of Pharmacological and Toxicological Methods, 2015
Sodium pentobarbital (Nembutal) is a barbiturate used in research as an anesthetic in many animal models. The injectable form of this drug has lately become difficult to procure and prohibitively expensive. Due to this lack of availability, researchers have begun to compound injectable sodium pentobarbital from so-called "nonpharmaceutical ...
Timothy P Geisbuhler
exaly   +3 more sources

Pentobarbital sodium and chromosome abnormalities in rabbit blastocysts

Experientia, 1975
Female rabbits were injected with pentobarbital sodium at 1/4 h or 6 h post coitum. A slight delay in oocyte maturation was evident in animals killed at 17 h pc, however, zygote development appeared normal by 24 h pc. At 6 days pc, a greater frequency of chromosomally abnormal blastocysts was found in animals injected with pentobarbital than in control
Evelyn L Shaver, E L Shaver
exaly   +3 more sources

Pentobarbital Sodium: Variation in Toxicity

Science, 1966
The survival rate of groups of female mice given a standard dose of pentobarbital sodium varied during a 12-hour period. When survival rate was plotted against time, a curve with several inflections was described.
H A, Lindsay, V S, Kullman
openaire   +2 more sources

Pentobarbital Sodium Anesthesia in the Syrian Hamster*

Journal of the American Pharmaceutical Association (Scientific ed.), 1946
The Syrian hamster (Cricetus auratus) was studied to determine an effective dosage of pentobarbital sodium in relation to the length and depth of general anesthesia produced. In general, the hamster has an apparently greater tolerance to pentobarbital sodium both in anesthetic and lethal doses than the rat, guinea pig, or rabbit.
F J, ORLAND, P M, ORLAND
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Hemodynamic effects of sodium pentobarbital in the bovine

Journal of Surgical Research, 1972
Abstract The effects of intravenous sodium pentobarbital (SP) were studied in 34 normal and in 7 calves with brisket disease (BD). Average increase in pulmonary artery pressure was 12 mm Hg for normal calves with no significant change in BD calves. Average increase in femoral artery pressure after a transient decrease was 24 mm Hg in normal calves ...
F L, Anderson, A C, Kralios, T J, Tsagaris, H, Kuida   +3 more
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Sodium Pentobarbital-Induced Mutations in the Hamster

Archives of Environmental Health: An International Journal, 1981
When virgin Syrian hamsters aged 6 to 8 wk were mated during estrus and anesthetized with sodium pentobarbital (Nembutal) 4 to 5 hr before estimated ovulation, pregnancy wastage in the newly conceived litter was observed. This was manifested by polyspermy of moribund eggs and death of fertilized eggs, deficits of expected zygotes, and triploidy and ...
T, Ito, T H, Ingalls
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Anesthesia in rabbits by intrahepatic sodium pentobarbital

Journal of Surgical Research, 1975
Abstract A reliable method for anesthesia of laboratory rabbits by intrahepatic injection of sodium pentobarbital was developed. Anatomical dissection was the basis for designation of external landmarks for injection. The advantages of the method have been simplicity, accuracy of dosage based on body weight, and an induction speed great enough for ...
R, Jacobs, D L, Krohn
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Inhibition of monoamine oxidase by sodium pentobarbital

Canadian Journal of Biochemistry, 1970
A single intraperitoneal injection of 30, 60, or 90 mg/kg of sodium pentobarbital into male rats produced an appreciable inhibition of monoamine oxidase activity of liver and heart. The brain and kidney activities were practically unaffected. Chronic administration of pentobarbital, 30 mg/kg daily for 20 days, did, however, produce an inhibition of ...
E, Quevedo, A, D'Iorio
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