Results 101 to 110 of about 34,150 (283)

Effects of Pentoxifylline on Nitric Oxide Levels and Histopathology of Pancreas in Diabetic Mice

open access: yesJournal of Ardabil University of Medical Sciences, 2018
Background & objectives: Several studies have shown that pentoxifylline is an antioxidant and anti-inflammatory agent. Pentoxifylline (PTX), has been shown to exert protective effects on autoimmune disorders.
Farin Malekifard   +3 more
doaj  

Safety of cilostazol in peripheral artery disease: a cohort from a primary healthcare electronic database

open access: yesBMC Cardiovascular Disorders, 2018
Background Cilostazol has been associated with spontaneous reports of cardiovascular adverse events and serious bleeding. The objective of this study is to determine the relative risk of cardiovascular adverse events or haemorrhages in patients with ...
Jordi Real   +9 more
doaj   +1 more source

Cardiovascular involvement in Kawaski Disease [PDF]

open access: yes, 2005
This article contains a case report of a 19 month old child with Kawasaki Disease who developed bilateral giant coronary artery aneurysms.peer ...
Chintala, Kavitha   +2 more
core  

On the assessment of the efficacy of pentoxifylline (Trental).

open access: yesJournal of medicine, 2017
The efficacy of Trental (pentoxifylline) in the treatment of intermittent claudication was evaluated in 14 double-blind randomized studies, involving 475 patients with chronic occlusive vascular disease. In twelve studies which were performed in the USA,
M. Rössner, R. Müller
semanticscholar   +1 more source

Release of Soluble Receptors for Tumor Necrosis Factor in Clinical Sepsis and Experimental Endotoxemia [PDF]

open access: yes, 2017
To assess the role of tumor necrosis factor (TNF) in the appearance of soluble TNF receptors (sTNFRs), 20 consecutive patients with a clinical diagnosis of sepsis were studied as were 7 chimpanzees after administration of endotoxin (4 ng/kg) with or ...
Gallati, Harald   +8 more
core  

Notch and NF-kB: Coach and Players of Regulatory T-Cell Resposnse in Cancer [PDF]

open access: yes, 2018
The Notch signaling pathway plays multiple roles in driving T-cell fate decisions, proliferation, and aberrant growth. NF-kB is a cell-context key player interconnected with Notch signaling either in physiological or in pathological conditions.
Bellavia, Diana   +5 more
core   +2 more sources

EMD273316 & EMD95833, type 4 phosphodiesterase inhibitors, stimulate fibroblastic-colony formation by bone marrow cells via direct inhibition of PDE4 and the induction of endogenous prostaglandin synthesis [PDF]

open access: yes, 2004
BACKGROUND: Type 4 phosphodiesterase (PDE4) inhibitors have been shown to stimulate bone formation in vivo and to stimulate osteoblastic differentiation in vitro.
Beier, Norbert   +2 more
core   +2 more sources

The Immunotherapeutic Effects of Pentoxifylline in Type 1 Diabetic Mice and its Effects on Expressions of Peroxisome proliferator-activated receptor gamma (PPARγ) gene

open access: yesArmaghane Danesh Bimonthly Journal, 2015
Background & aim: Pentoxifylline is an immunomodulatory and anti-inflammatory agent which inhibits the production of proinflammatory cytokines. The purpose of this study was to evaluate the effect of pentoxifylline in the treatment of type 1 diabetes in
F Malekifar   +4 more
doaj  

Efficacy of pentoxifylline treatment for neonatal sepsis: a meta-analysis of randomized controlled studies

open access: yesItalian Journal of Pediatrics, 2019
Introduction Pentoxifylline may be an important approach to treat neonatal sepsis. However, its use has not been well established. We conduct a systematic review and meta-analysis to evaluate the efficacy of pentoxifylline treatment for neonatal sepsis ...
Jun Tian   +3 more
doaj   +1 more source

Pharmacotherapy for Nonalcoholic Fatty Liver Disease [PDF]

open access: yes, 2015
Lifestyle modifications and optimization of the management of cardiometabolic comorbidities are currently the mainstay of treatment for patients with nonalcoholic fatty liver disease.
Chalasani, Naga, Gawrieh, Samer
core   +2 more sources

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