Results 201 to 210 of about 173,142 (253)

The Development and Pilot Clinical Study of CD147 Targeted Antagonistic Peptide Probe for Tumor Imaging

Advanced Science, EarlyView.
This study establishes [68Ga]Ga‐DOTA‐AP9 as a first‐in‐human CD147‐targeted PET tracer with favorable safety and specific tumor uptake. Tracer accumulation correlates with CD147 expression in patients, enabling noninvasive quantification of CD147‐positive malignancies.
Xiaokun Ma, Rui Guo, Dongfeng Niu, Yufei Song, Zhenyao Zhang, Xiangxi Meng, Lili Mao, Haifeng Huang, Hua Zhu, Zhi Yang, Teli Liu   +10 more
wiley   +1 more source

Disability Studies and Disability Evaluation in Healthcare-Themes and Challenges Moving Forward. [PDF]

Healthcare (Basel)
Harley DA, Chao SY.
europepmc   +1 more source

People-Centered Care

People-Centered Care
openaire  

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Development of a Patient Journey Map for Metabolic Dysfunction-Associated Steatohepatitis: A Comprehensive Assessment of the Patient Journey in North America. [PDF]

J Patient Exp
Garcia DO, Calle RA, Seth A, Norton TD, Lederer DJ, Richardson A, Berg J, Betel M, Chang H, Daniels H, Eskridge W, McIntyre J, Villiotti Madison G, Villiotti T, Sellati R.   +14 more
europepmc   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Towards palliative care for all: Translation and cross-cultural adaptation of the Supportive and Palliative Care Indicators Tool-4ALL (SPICT-4ALL) to the Tamil healthcare context in India and Sri Lanka. [PDF]

Palliat Support Care
I C SP, Prathapan S, Kuriakose J, Ratnasingam G, Pricilla S RA, Rahman SM, Munday D, Boyd K, Murray SA, Fernando GVMC, Sundararaj JJ.   +10 more
europepmc   +1 more source

Large‐Scale Genomics Reveals Three‐Source Ancestry and Layered Adaptation to High Altitude in Tibetan Chickens

Advanced Science, EarlyView.
Whole‐genome analysis of 1,054 chickens reveals three ancestral sources (NWC, SYA, and SHF) with distinct temporal entry patterns into the Tibetan Plateau. Route‐specific selection scans, calibrated against a demographic null, suggest complementary functional enrichments—vascular homeostasis (NWC), calcium signaling and cardiac adaptation (SYA), and ...
Zongyi Zhao, Ruixue Nie, Hailu Fan, Tenzin Ngodroup, Li Zhu, Hongbin Pan, Bo Zhang, Hao Zhang   +7 more
wiley   +1 more source

Supporting people with type 2 diabetes mellitus through the REDE D+ social prescribing program: feasibility of a non-randomized pilot study. [PDF]

Front Public Health
Oliveira D, Henriques A, Nogueira P, Costa A.   +3 more
europepmc   +1 more source

Practices and experiences of nursing staff delivering acute care for people with dementia in surgical-medical wards in Chile: qualitative study. [PDF]

Alzheimers Dement
Oliveira D, Catalán L, Bozanic A, Pedrero V, Miranda-Castillo C, Brun P.   +5 more
europepmc   +1 more source