Results 61 to 70 of about 15,101,330 (355)

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

open access: yesFEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang   +7 more
wiley   +1 more source

Assessing Compliance with Indigenous Self-Determination Standards: A Comparative Analysis of Chile, Colombia, and Mexico

open access: yesSocieties
Recent advancements have been observed in the global legal framework, particularly in the recognition of Indigenous peoples’ rights, among which the right to self-determination stands out.
Martha Angélica Ramírez Salazar   +5 more
doaj   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

open access: yesFEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

British Monarchy: from the Past to the Future?

open access: yesНаучно-аналитический вестник Института Европы РАН
The article shows the traditions of the British monarchy and at the same time steps towards its modernization. The authors return to long-standing discussions about the possibility of republicanism prevailing in the United Kingdom.
Galina S. Ostapenko   +1 more
doaj   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

open access: yesFEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng   +2 more
wiley   +1 more source

Les mots du « peuple » dans le Calepino

open access: yesCahiers d’Études Romanes, 2017
This paper focuses on the lexicological and semantic study of the Latin words expressing the notion of people: gens, natio, plebs, populus, proletarii, turba and vulgus in Calepino’s multilingual dictionary, within four reference editions representing ...
Béatrice Charlet-Mesdjian   +1 more
doaj   +1 more source

Resurrecting the UK Historic Sector National Accounts [PDF]

open access: yes
The UK national accounts do not provide a full long-run set of historic data describing the behaviour of the UK's private sector. Although comprehensive figures are available from 1987, the pre-1987 historic sector national accounts are marred by ...
Bill Martin
core   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

open access: yesAging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath   +3 more
wiley   +1 more source

Abortion experiences and preferences of transgender, nonbinary, and gender-expansive people in the United States [PDF]

open access: hybrid, 2020
Heidi Moseson   +10 more
openalex   +1 more source

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