Results 1 to 10 of about 656,092 (295)

A Systemically Administered Humanized Anti-Nav1.7 Antibody with Long-Lasting Analgesic Activity and Preserved Physiological Nociception

Pharmaceutics
Background: Neuropathic pain remains difficult to treat because current analgesics often provide insufficient efficacy or dose-limiting adverse effects.
Sosuke Yoneda, Daisuke Uta, Kana Yasufuku, Takuya Yamane, Saho Yoshioka, Keiko Takasu, Takaya Izumi, Sayaka Fujita, Daiki Nakamori, Shiori Kawasaki, Tatsuya Takahashi, Mai Yoshikawa, Koichi Ogawa, Erika Kasai   +13 more
doaj   +1 more source

The study of pharmacodynamics of a medicine based on humanized monoclonal antibodies against IL-17 in rabbit model of antigen-induced arthritis

Биопрепараты: Профилактика, диагностика, лечение, 2018
The present article contains scientific data on the assessment of specific activity of therapeutic humanized monoclonal antibodies against IL-17 in rabbit model of antigen-induced arthritis.
A. A. Nedorubov, A. V. Grachev, M. A. Varavko, E. L. Morozova   +3 more
doaj  

Therapeutic biologics interference in serological and pre-transfusion testing. [PDF]

Front Immunol
Trummer P, Habicht CP, Scharberg EA, Schneeweiß C.   +3 more
europepmc   +1 more source

Antiviral activity of non-neutralizing antibodies during steady-state HIV-1 infection in humanized mice. [PDF]

iScience
Nair MS, Chong S, Liu M, Yu J, Wang M, Huang Y, Ho DD.   +6 more
europepmc   +1 more source

Relapsed/refractory multiple myeloma with extramedullary plasmacytomas successfully rechallenged with humanized B-cell maturation antigen-directed chimeric antigen receptor T-cell immunotherapy in an advanced disease stage: A case report. [PDF]

Exp Ther Med
Zhang R, Cheng L, Liu J, Zhang L, Zhuang J.   +4 more
europepmc   +1 more source

Therapeutic Applications of Immunobiologics in Autoimmune and Inflammatory Diseases. [PDF]

Pharmaceutics
Narayanan KB.
europepmc   +1 more source

Obinutuzumab for Rituximab-Intolerant Minimal Change Disease: A Case Report and Review of Recent Literature. [PDF]

Cureus
Shan HY.
europepmc   +1 more source

A Narrative Review of Amyloid-β Monoclonal Antibodies for Alzheimer Disease: How Amyloid Species Engagement May Affect Clinical Outcomes. [PDF]

Neurologist
Caselli RJ, Geldmacher DS, Schilling TB.
europepmc   +1 more source

A dual-action humanized DKK-1 antibody that activates the Wnt/β-catenin signaling pathway and inhibits the RANKL signaling pathway for osteoporosis therapy. [PDF]

Front Immunol
Hou S, Gao T, Wu Y, Wang H, Zhang D, Guo Q, Xu J, Guo H, Qian W.   +8 more
europepmc   +1 more source

Humanized Antibodies Targeting Ectodomains of IL-6R and GP130 Suppress IL-6/STAT3 Signalling and Tumour Growth in Breast Cancer Models. [PDF]

J Cell Mol Med
Pereira SD, Baipadithaya G, Prasad K, Naha R, Acharya LP, Gopalakishna GPU, Periasamy R, Chandrashekar A, Bhat S, Joshi MB, Satyamoorthy K.   +10 more
europepmc   +1 more source