Results 181 to 190 of about 68,712 (302)

Synergistic Sunlight‐Activated Photodynamic and Near‐Infrared‐Induced Mild Photothermal Therapy for Infected Wound Healing Using Functionalized Nano‐Bi2WO6 Composites

Advanced Science, EarlyView.
This work proposes a multifunctional Bi2WO6:Yb,Er@CuS@CS nanocomposite that integrates photodynamic therapy (PDT), near‐infrared‐triggered photothermal therapy (PTT), and Cu2+ release for infected wound repair. The nanocomposite demonstrates enhanced antibacterial efficacy via combined PDT, PTT, and Cu2+ release, effective immunomodulatory by mild ...
Yihao Sun, Liangrui He, Zhijun Shen, Yuxin Zhang, Yizhang Tang, Xujiang Yu, Jisi Zheng, Moran Huang, Wanwan Li, Lei Wang   +9 more
wiley   +1 more source

Estimating the population size of people who inject drugs in Canada, 2021. [PDF]

Can Commun Dis Rep
Williams A, Sorge J, Périnet S, Yang Q, Cox J, Bonn M, Smoke A, Popovic N.   +7 more
europepmc   +1 more source

m5C‐Modified tRF3b‐CysGCA‐23 Suppresses Bladder Cancer Malignancy by Repressing H3K18 Lactylation via Stabilizing RBM4

Advanced Science, EarlyView.
In this study, we identified an NSUN6‐dependent m5C‐modified tsRNA, m5C‐tRF3b CysGCA‐23 (mtRC), that is downregulated in BC and inversely correlated with disease progression. Mechanistically, mtRC suppresses BC malignancy by stabilizing RBM4, attenuating glycolysis, and thereby limiting H3K18 lactylation–mediated activation of IL1RAP and VASH2 ...
Xiaoling Ying, Yapeng Huang, Jian Huang, Qinyu Cai, Danni Zhang, Cong Chen, Yuxi Nie, Baotong Yang, Chuan Li, Wenyu Hu, Chang Xiong, Chengcheng Zhang, Ding Ji, Yaomin Liang, Mei Yang, Wenqi Wu, Weidong Ji   +16 more
wiley   +1 more source

Managing tuberculosis in people who use and inject illicit drugs

Bulletin of the World Health Organization, 2013
Haileyesus Getahun, Annabel Baddeley, Mario Raviglione   +2 more
doaj   +3 more sources

Implementation of low dead space syringes in response to an outbreak of HIV among people who inject drugs: a response to Kesten et al. [PDF]

, 2017
Campbell, John, Goldberg, David J., Hunter, Carole, McAuley, Andrew, Milosevic, Catriona   +4 more
core   +1 more source

POU2F1 Promotes Chemoresistance in Colorectal Cancer Cells via Attenuates the MDR2 Degradation Mediated by PPP1R11 Lactylation

Advanced Science, EarlyView.
Schematic diagram of our study showing that highly expressed POU2F1 in colorectal cancer (CRC) can directly accelerate the cytosolic lactate export to decrease PPP1R11 lactylation at K59, thereby attenuating the E3 ligase enzyme activity and protein stability of PPP1R11, which inhibits the ubiquitination of MDR2 at K413 and K538 but increases the ...
Longzheng Xia, Jinguan Lin, Xianjie Jiang, Linda Oyang, Shiming Tan, Zongyao Ren, Qiu Peng, Qianjin Liao, Yujuan Zhou   +8 more
wiley   +1 more source

Evaluation of a "one-stop shop" for integrated harm reduction and primary care for people who inject drugs. [PDF]

PLoS One
Ibrahim N, Jones S, Rich K, Alvarez L, Price C, Kil N, Altice FL, Meyer JP.   +7 more
europepmc   +1 more source

Assessing the impact of a temporary class drug order on ethylphenidate-related infections among people who inject drugs in Lothian, Scotland: an interrupted time–series analysis [PDF]

, 2017
Amsterdam, Bernal, Caulkins, Dahlman, Darke, Dunsmuir, Dunsmuir, Giese, Greenfield, Griffith, Griffiths, Hill, Karila, Kontopantelis, Lafferty, Larney, Levine, Lindsay, Loeffler, Luca-Harari, Manea, McAuley, Parks, Reuter, Ryall, Rácz, Rácz, Smyth, Soussan, Taljaard, Van Hout, Wagner, Wilkins, Wood   +33 more
core   +1 more source

A Chirality‐Converted Bacteriolytic Dodecapeptide Regulates Vibrio‐Induced Polymicrobial Infection and Ameliorates Invasion‐Associated Gut Microbiota Disequilibrium

Advanced Science, EarlyView.
Multidrug‐resistant Vibrio infections are rising rapidly and threaten coastal populations worldwide. This study introduces D‐zp37, a chirality‐engineered antimicrobial peptide with exceptional potency against resistant Vibrio species. D‐zp37 kills planktonic cells, blocks mixed‐species biofilms, disrupts essential bacterial stress responses, and shows ...
Ping Zeng, Qipeng Cheng, Xiaoxu Zhang, Honglan Wang, Jinghan Zhang, Xinyi Ding, Pengfei Zhang, Lanhua Yi, Kwok‐Yin Wong, Kin‐Fai Chan, Sheng Chen, Sharon Shui Yee Leung   +11 more
wiley   +1 more source

Clinical Spectrum of Infections Among People Who Inject Drugs, With Special Reference to Infective Endocarditis. [PDF]

Cureus
Hussain A, Talukdar AJ, Mitra S, Dutta S, Phukan C, Singha S.   +5 more
europepmc   +1 more source