Results 181 to 190 of about 13,383,705 (258)

P27 Hepatitis B outreach to people who inject drugs (PWID)

Journal of Virus Eradication, 2017
L. Kanaef
doaj   +1 more source

An update on bloodborne viruses among people who inject drugs in South Asia. [PDF]

Harm Reduct J
Rahman MF, Khan MSI, Shiddiky MJA, Huda MM, Mondal UK, Jahan N, Mahmood S, Ross AG.   +7 more
europepmc   +1 more source

OAF Blocks SIAH1‐Mediated Degradation of SCPX, a Therapeutic Strategy for MASLD

Advanced Science, EarlyView.
This study shows OAF directly binds to SCPX and inhibits its interaction with the E3 ligase SIAH1, thereby protecting SCPX from ubiquitin‐dependent degradation and stabilizing its levels. This OAF‐SCPX axis represents a novel pathway in lipid homeostasis, highlighting OAF as a promising therapeutic candidate for MASLD.
Zongxi Li, Jingyue Song, Kaili Ma, Shunan Tang, Shuqian Wang, Wenya Ji, Chen Lu, Ting Zhang, Huaping Zheng, Xiaowei Zheng, Shanshan Lai, Cheng Deng   +11 more
wiley   +1 more source

Daily polysubstance use associated with HIV, HCV, and non-fatal overdose among people who inject drugs: A latent class analysis using nationwide data. [PDF]

Drug Alcohol Depend
Cadet K, Musci R, Johnson RM, Flynn C, German D, Linton SL, Group TNS.   +6 more
europepmc   +1 more source

Oral Nanomicelle‐Mediated Sequential Butyrate Production in the Intestine for Ulcerative Colitis and Immunosuppression Treatment

Advanced Science, EarlyView.
After oral administration, inodorous GLU‐BA self‐assembles into nanomicelles in aqueous environments to resist premature gastric adsorption. Upon reaching the intestine, endogenous esterases rapidly cleave the built‐in ester bonds in these nanomicelles to release BA and GLU, with GLU further metabolized by gut microbiota to gradually generate BA ...
Feifei Xin, Zhike Xie, Danyue Zhao, Lin Yang, Yiqun Wan, Zuwei Liu, Situ Xiong, Ying Zhang, Lei Feng, Hao Wan   +9 more
wiley   +1 more source

A precision randomized trial of hepatitis C treatment support among people who inject drugs in India: The STOP-C trial. [PDF]

J Hepatol
Solomon SS, Srikrishnan AK, McFall AM, Baishya J, Gunaratne MP, Kedar A, Amrose P, Balakrishnan R, Boobalan J, Evans J, Lau BM, Ehrhardt S, Sulkowski MS, Thomas DL, Lucas GM, Kumar MS, Mehta SH.   +16 more
europepmc   +1 more source

Enteric ChAT‐Expressing Neurons Mediate the Protective Effect of Lactobacillus plantarum in Inflammatory Bowel Disease

Advanced Science, EarlyView.
In colitis patients and mice, reduced Lactobacillus abundance is observed. Experimental studies show that L. plantarum A736 metabolizes dietary tryptophan into indole‐3‐lactic acid (ILA), while both L. plantarum A736 and ILA impact ChAT‐expressing enteric neurons and acetylcholine levels, thereby regulating intestinal immune responses and alleviating ...
Bing Xia, Yuwei Sun, Jialin Wang, Yike Liu, Lu Wang, Shiqi Jiang, Gaiyan Bai, Ruijing Zhang, Yu Zhang, Rongwei Kou, Danna Wang, Beita Zhao, Junjie Yi, Yu Fu, Xiaoning Liu, Xuebo Liu   +15 more
wiley   +1 more source

Antiretroviral therapy use and CD4 cell count among people who inject drugs living with HIV in southern Vietnam. [PDF]

BMC Infect Dis
Thanh DC, Boettiger DC, Abdul-Quader A, Thanh Ha HT, Thang PH.   +4 more
europepmc   +1 more source

Chemotherapy‐Activated GSK3β‐DNMT1 Signaling Upregulates CD47 to Evade Macrophage Phagocytosis and Drive Temozolomide Resistance in Glioblastoma

Advanced Science, EarlyView.
Temozolomide treatment activates GSK3β, driving DNMT1 phosphorylation, destabilization, and CD47 promoter hypomethylation in glioblastoma. This epigenetic shift upregulates CD47, enabling TMZ‐treated GBM cells to evade macrophage phagocytosis, survive chemotherapy, and acquire resistance.
Jie Li, Shuai Ying, Yi Zhang, Jingjing Wang, Quan Wan, Lingli Gong, Daxing Xu, Zhenkun Yang, Hongnian Lu, Ying Yin, Xiangming Fang, Zhening Pu   +11 more
wiley   +1 more source

Sex work or male-with-male sexual activity and the risks of HIV and hepatitis C acquisition among people who inject drugs: a global systematic review and meta-analysis. [PDF]

EClinicalMedicine
Dawe J, Trickey A, Walker J, Barrass L, Njiro BJ, Kundu B, Hickman M, Abramovitz D, Aladashvili M, Artamonova I, Blouin K, Boyd A, Bruneau J, DeBeck K, Jarlais DD, Dietze P, Dumchev K, Hankins C, Hatzakis A, Havens JR, Hope V, Hayashi K, Jongen V, Kurth A, Maher L, Mehta S, Mitchell H, Morris MD, Page K, Palmateer NE, Platt L, Prins M, Rathnayake K, Saraswati LR, Roussos S, Sacks-Davis R, Sarna A, Solomon S, Strathdee SA, Sypsa V, Van Santen D, Zang G, Stone J, Vickerman P, Artenie AA.   +44 more
europepmc   +1 more source