Results 51 to 60 of about 69,395 (344)

A descriptive study of hepatitis C in people who inject drugs

Indian Journal of Medical Research, 2023
Background & objectives: The seroprevalence of the hepatitis C virus (HCV) in general population is higher than that of human immunodeficiency virus (HIV) in India. People who inject drugs (PWIDs) constitute a high-risk group for all blood-borne infections.
Shivaprakash, Prakrithi, Patel, Vinit, Shadakshari, Darshan, Verma, Rahul, Shukla, Lekhansh, Mahadevan, Jayant, Kandasamy, Arun, Chand, Prabhat Kumar, Benegal, Vivek, Sethuraman, Lakshmanan, Sharma, Priyamvada, Murthy, Pratima   +11 more
openaire   +2 more sources

Healthcare avoidance by people who inject drugs in Bangkok, Thailand [PDF]

Journal of Public Health, 2015
Although people who inject drugs (IDU) often contend with various health-related harms, timely access to health care among this population remains low. We sought to identify specific individual, social and structural factors constraining healthcare access among IDU in Bangkok, Thailand.Data were derived from a community-recruited sample of IDU ...
A.J. Heath, Thomas Kerr, Kanna Hayashi, Paisan Suwannawong, Lianping Ti, Karyn Kaplan, Evan Wood   +6 more
openaire   +2 more sources

Evaluation of an online injecting drug use stigma intervention targeted at health providers in New South Wales, Australia

Health Psychology Open, 2017
People who inject drugs are highly stigmatised. Discriminatory experiences are commonly reported, particularly in health care settings. This article evaluates an online stigma reduction training module targeting health providers working with people who ...
Loren Brener, Elena Cama, Peter Hull, Carla Treloar   +3 more
doaj   +1 more source

Association between harm reduction intervention uptake and skin and soft tissue infections among people who inject drugs [PDF]

, 2017
Background: Bacterial skin and soft tissue infections (SSTIs) are a health issue for people who inject drugs (PWID). There is a lack of evidence on the associations between harm reduction (HR) uptake and SSTIs.
Dunleavy, Karen, Goldberg, David, Hutchinson, Sharon, Knox, Tony, Munro, Alison, Palmateer, Norah, Roy, Kirsty, Taylor, Avril   +7 more
core   +5 more sources

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Trauma in the childhood stories of people who have injected drugs [PDF]

Addiction Research & Theory, 2015
Aim: To document childhood trauma in the life stories of people who have injected drugs. Method: Fifty-five participants (38 m, 17 f) recruited via Scottish recovery networks, who had injected drugs in the previous five years, were interviewed by peer researchers using the Life Story method.
Dalgarno, Phil, Hammersley, Richard, Reid, Marie, Jack, Moria, Liddell, David, McCollum, Sean, Smart, Audrey, Smith, Austin, Strike, Yvonne, Wallace, Jason, Thompson, Alan   +10 more
openaire   +3 more sources

HIV Epidemics in the European Region: Vulnerability and Response [PDF]

, 2015
This report provides a systematic review of the evidence on HIV vulnerability and response in all 53 countries of the WHO European Region, stretching from Iceland to the borders of China.
Hickson, F, Hope, V, Jolley, E, Latypov, A, Platt, L, Reynolds, L, Rhodes, T, Vickerman, P   +7 more
core   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

Population estimation and harm reduction among people who inject drugs in Addis Ababa, Ethiopia

Harm Reduction Journal, 2020
Background Injecting drug use is known to contribute significantly to the spread of the HIV epidemic in many parts of the developing world. Due to the hidden nature and stigma of the problem, it is difficult to study using routine surveys.
Negussie Deyessa, Bekele Senbete, Aman Abdo, Bernard M. Mundia   +3 more
doaj   +1 more source

Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo

FEBS Open Bio, EarlyView.
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu, Yan Tao, Shan Wu, Yuwen Gong, Youli Zhao, Shaomin Niu, Hui Cheng, You Mu, Na Xu, Ying Wang, Jianzhong Lu, Shanhui Liu, Lanlan Li   +12 more
wiley   +1 more source