Results 141 to 150 of about 1,466,572 (302)

HIV and drugs: a common, common-sense agenda for 2016

The Lancet Global Health, 2016
Kent Buse, Eliot Albers, Shiba Phurailatpam   +2 more
doaj   +1 more source

Lysosome‐Acidifying Nanoparticles Rescue A30P α‐Synuclein Induced Neuronal Death in Cellular and Drosophila Models of Parkinson's Disease

Advanced Healthcare Materials, EarlyView.
Lysosome‐targeted acidic nanoparticles based on a biodegradable poly(ethylene tetrafluorosuccinate‐co‐succinate) copolymer are engineered to restore impaired lysosomal acidification through pH‐responsive intracellular degradation. Localized acid release enhances autophagic proteolysis, reduces α‐synuclein accumulation, and preserves dopaminergic neuron
Chih Hung Lo, Mengda Ren, Gavin Wen Zhao Loi, Eka Norfaishanty Saipuljumri, Jonathan Indajang, Kah Leong Lim, Jialiu Zeng   +6 more
wiley   +1 more source

Psychosocial consequences of xylazine and implications for harm reduction services

Drug and Alcohol Dependence Reports
Introduction: Xylazine, a veterinary tranquilizer not approved for human use, has increasingly contaminated the unregulated drug supply in the United States and is a key driver of an increasingly synthetic, polysubstance overdose crisis.
Marina Plesons, William H. Eger, Erika L. Crable, Maia H. Hauschild, Corbin C. McElrath, Cyrus Owens, David W. Forrest, Angela R. Bazzi, Naida De Los Santos, Hansel E. Tookes, Tyler S. Bartholomew   +10 more
doaj   +1 more source

Primary Care and Prescription Drugs: Coverage, Cost-Sharing, and Financial Protection in Six European Countries [PDF]

, 2010
Examines health coverage, innovations in cost-sharing design, and affordability of primary care and prescription drugs in Denmark, France, Germany, the Netherlands, Sweden, and the United Kingdom. Explores lessons for U.S.
Elias Mossialos, Sarah Thomson
core  

Coacervates Made of Elastin‐Like Polypeptides Fused with Melanocyte‐Stimulating Hormone and Monocyte Chemoattractant Protein Enhance Skin Wound Healing in Spinal Cord‐Injured Mice

Advanced Healthcare Materials, EarlyView.
Pressure skin wounds are frequent complications after spinal cord injury (SCI), with impaired healing due to vascular and immune deficits. Elastin‐like polypeptides (ELP) fused to α‐MSH (MSH‐ELP) or MCP‐1 (MCP‐ELP) are developed and tested on these wounds. The resulting nanoparticles are non‐toxic and bioactive, and they enhance macrophage recruitment,
Suneel Kumar, Dhruv Patel, Greeshma Manjunath, Shashank Madhavan, Ashley Mathew, Dnyaneshwari Rananavare, Jahnavi Shah, Francois Berthiaume   +7 more
wiley   +1 more source

Housing assistance among people who are unstably housed and use drugs in Oregon: a cross-sectional study

BMC Public Health
Background Unstable housing has tremendous harms on health and well-being and people who use drug experience significant barriers to housing. The objectives of this study were to estimate the prevalence of housing assistance among people who use drugs ...
Esther O. Chung, Lynn D. Wenger, Danielle Good, Gillian Leichtling, Morgan Godvin, Barrot H. Lambdin, Alex H. Kral   +6 more
doaj   +1 more source

Pathways to Addiction: A Gender-Based Study on Drug Use in a Triangular Clinic and Drop-in Center, Kerman, Iran [PDF]

Background: Addiction is characterized differently among women and men, and they begin using drugs for different reasons and motives. Objectives: The aim of the study was to explore the gendered experiences and patterns of illicit drug use initiation ...
Haghdoost, Ali Akbar, Karamouzian, Mohammad, Mahdavian, Mina, Zolala, Farzaneh   +3 more
core  

Engineering Extracellular Vesicle Production Through Magnetic Ion Channel Activation for Bone Regeneration

Advanced Healthcare Materials, EarlyView.
Magnetic Ion Channel Activation (MICA) enables remote stimulation of mechanosensitive ion channels using functionalised magnetic nanoparticles, enhancing extracellular vesicle (EV) biogenesis is pre‐osteoblasts. MICA desrived EVs exhibit typical nano‐vesicular characteristics but display superior pro‐osteogeneic activity, promoting mesenchymal stem ...
Afeesh Rajan Unnithan, Kenny Man, Kritika, Lee A. Gethings, Christopher J. Hughes, Alicia Keenan, Liam Heaney, Sophie C. Cox, Owen G. Davies, Alicia J. El Haj   +9 more
wiley   +1 more source

Ensuring that people who use drugs are safely and equitably included at meetings and conferences

Journal of Critical Public Health
Collaborating with people who use or used drugs (PWUD) in research and policy fora and incorporating their perspectives in decision-making processes is a crucial step towards mitigating drug policy-related harm.
Hannah L Brooks, Shay J. Vanderschaeghe, Nicole D. Gehring, Shanell Twan, Marliss Taylor, Elaine Hyshka   +5 more
doaj   +1 more source

Oxygen Supply of Islets of Langerhans by Photosynthetically Active Microalgae in Bioprinted Co‐Cultures Maintains Their Function in a Hypoxic Environment

Advanced Healthcare Materials, EarlyView.
This study developed a bioprinted co‐culture system embedding rat pancreatic islets and Scenedesmus sp. microalgae spatially defined in close vicinity. Red light was found optimal to ensure microalgal photosynthesis while maintaining islet viability and functionality. A tailored co‐culture medium supported both cell types.
Finn Dani, Sarah Duin, Ashwini Rahul Akkineni, Susann Lehmann, Barbara Ludwig, Michael Kühl, Michael Gelinsky, Anja Lode   +7 more
wiley   +1 more source