Results 151 to 160 of about 46,557 (263)

SGLT‐2 Inhibitors are Associated With a Lower Risk of Multiple Myeloma

European Journal of Haematology, EarlyView.
ABSTRACT Aims We aimed to investigate drug response of sodium‐glucose transport protein‐2 inhibitors (SGLT2i) in multiple myeloma (MM), as SGLT2i have potential favorable effects on conditions related to MM. Methods We conducted a pharmacoepidemiologic study with a US nationwide health insurance claim data using Cox models to investigate the ...
Enze Liu, Anna Sun, Yuedi Yang, Jing Xu, Attaya Suvannasankha, Brian A. Walker, Pengyue Zhang   +6 more
wiley   +1 more source

Pepsin-driven corrosion of orthodontic titanium alloys in candidiasis-simulated saliva: electrochemical and statistical insights. [PDF]

Sci Rep
El-Kamel RS, Fekry AM.
europepmc   +1 more source

Retrospective comparison of treatments for equine gastric ulceration syndrome and the influence of inflammatory bowel disease

Equine Veterinary Education, EarlyView.
Summary Background Equine squamous gastric disease (ESGD) and equine glandular gastric disease (EGGD) can be treated with oral omeprazole, combined with sucralfate or an extended‐release intramuscular omeprazole (ERIO). Objectives To evaluate these different treatments for ESGD and EGGD and assess the influence of inflammatory bowel disease (IBD) on ...
L. C. Kranenburg, C. Ludin, D. A. van Doorn, M. M. Sloet van Oldruitenborgh‐Oosterbaan, P. Witt, R. M. A. C. Houben, R. van den Boom   +6 more
wiley   +1 more source

Lactoferrin and Its Enzymatic Hydrolysates as Natural Antimicrobial and Antioxidant Agents for Food Preservation. [PDF]

Foods
Gruden Š, Lorbeg PM, Matijašić BB, Skrt M, Leonardi A, Križaj I, Poklar Ulrih N.   +6 more
europepmc   +1 more source

Tyrosine residues at the substrate binding site in human NQO1 homodimer: Protein conformational dynamics and optimization of substrate binding geometry

The FEBS Journal, EarlyView.
Human NAD(P)H:quinone oxidoreductase 1 is a homodimeric flavoenzyme crucial for redox metabolism and linked to significant health issues. Point mutations at Tyr126 and Tyr128 demonstrate their essential roles in optimizing substrate binding geometry for catalysis, as well as in half‐site reactivity and conformational dynamics during the enzyme's ...
Maribel Rivero, Juan Luis Pacheco‐Garcia, Pavla Vankova, Dmitry Loginov, Isabel Quereda‐Moraleda, Jose Manuel Martin‐Garcia, Petr Man, Angel Luis Pey, Milagros Medina   +8 more
wiley   +1 more source

The Impact of Acid-Free Reflux on Vocal Cord Granuloma. [PDF]

Laryngoscope Investig Otolaryngol
Liu XH, Qiang Y, Xie M, Cao N, Yan YX, Zhao JW, Ren JL, Luo HN.   +7 more
europepmc   +1 more source

A guide to laser microdissection‐based proteomics

The FEBS Journal, EarlyView.
This review takes researchers through the full laser microdissection proteomics workflow—from tissue preparation and image analysis to sample processing and mass spectrometry—offering practical solutions to common challenges at each step. Real‐world examples from across the field illustrate how the technology is being applied to disease tissue, making ...
Cheng Shen, Kael Schoffer, Charlotte Williams, Maria C. Tanzer   +3 more
wiley   +1 more source

A Native Nepenthesin Reactor for Improved Proteolytic Digestion of Intrinsically Disordered Proteins in Proteomics Workflows. [PDF]

Chembiochem
Wall C, Hause F, Grimm W, Otto FW, Siefke E, Kipping M, Sinz A.   +6 more
europepmc   +1 more source

Directional information flow in human frataxin defines allosteric pathways connecting the hydrophobic core to the iron‐binding ridge

The FEBS Journal, EarlyView.
Human frataxin deficiency causes Friedreich's ataxia, yet how iron‐binding events are communicated across the protein is unclear. Using transfer entropy analysis of molecular dynamics simulations, we identify buried hydrophobic core leucines (LEU136, LEU140) as the source of directional signaling toward the iron‐binding acidic ridge.
Kevser Kübra Kırboğa, Ecir Uğur Küçüksille   +1 more
wiley   +1 more source

Autonomous Hydrogel Actuators Programmed by Endogenous Biochemical Logic for Dual-Stage Morphing and Drug Release. [PDF]

Adv Mater
Liu Y, Potthuri H, Sosnik A, Khoury LR.
europepmc   +1 more source