Results 201 to 210 of about 46,557 (263)

Evaluation of Large Language Models in the Clinical Management of Patients With Upper Gastrointestinal Bleeding: Insights From Real‐World Patient Data

DEN Open, Volume 7, Issue 1, April 2027.
Large language models are evaluated for pre‐endoscopy risk stratification and prediction of endoscopic findings in patients with upper gastrointestinal bleeding. Their performance is compared with validated clinical risk scores, conventional machine learning models, and hybrid approaches.
Mohsen Rajabnia, Farbod Davoodi, Mahsa Hajisafarali, Shadi Asadinia, Mahsa Shiri, Fatemeh Shirzad, Peyman Saeedi, Mahsa Mohammadi   +7 more
wiley   +1 more source

Melatonin alleviates chronic intermittent hypoxia-induced gastric mucosal injury via attenuation of oxidative stress and JNK-mediated apoptotic signaling in rats. [PDF]

PLoS One
Ji HL, Yu HL, Luo JF, Li XR, Nie CX, Liu TJ, Jiang HH, Liu CH, Zhang JB, Yuan XH, Song XF, Li YD, Ge Y, Fu AS.   +13 more
europepmc   +1 more source

Innovative Therapeutic Endoscopy of the Upper Gastrointestinal Tract: Review of the Japan Gastroenterological Endoscopy Society Core Sessions

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT The Japanese Gastroenterological Endoscopy Society (JGES) established four core sessions on endoscopic treatment for upper gastrointestinal diseases under the theme ‘Innovative Therapeutic Endoscopy’ between 2023 and 2024. This review summarizes these sessions and compiles them as a conference report. At the 105th JGES Core Session, 14 studies
Mikitaka Iguchi, Tomoki Michida, Yasuhiko Abe, Hisashi Doyama, Noriya Uedo, Hajime Isomoto, Masayuki Ohta, Junko Fujisaki   +7 more
wiley   +1 more source

Quinoa protein hydrolysates: antioxidant properties and cytoprotection against D-galactose-induced oxidative stress. [PDF]

Front Nutr
Yang C, Yang C, Zhou Y, Ma J, Wei Y, Huang J.   +5 more
europepmc   +1 more source

Update on Sedation for Upper Gastrointestinal Endoscopy in Japan: Current Evidence on Remimazolam

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Sedation is an essential component of upper gastrointestinal endoscopy because it reduces patient discomfort and anxiety while improving patient acceptance and procedural quality. In Japan, benzodiazepines such as midazolam and opioid analgesics have long been widely used in routine clinical practice; however, many of these agents historically
Ryoji Ichijima, Masahiro Toyama, Taiki Shishido, Yuki Koyo, Takehiro Yoshii, Reona Kawamura, Tsubasa Ishikawa, Yasuhiko Mizuguchi, Naoya Toyoshima, Hiroyuki Takamaru, Masayoshi Yamada, Masau Sekiguchi, Seiichiro Abe, Yutaka Saito   +13 more
wiley   +1 more source

The Reconstruction of Sesame Protein-Derived Amyloid Fibrils Alleviates the Gastric Digestion Instability of β-Carotene Nanoparticles. [PDF]

Nanomaterials (Basel)
Zhang L, Zhang P, Tong H, Zhao Y, Yu T, Liu G, Liu D.   +6 more
europepmc   +1 more source

Dynamic Surface‐Enhanced Raman Scattering Platform With Multiscale Nanostructural Engineering and Programmable Surface Energy for Artificial Intelligence‐Assisted Discrimination of Helicobacter pylori

Advanced Oncology, Volume 1, Issue 1, December 2026.
This study develops a dynamic surface‐enhanced Raman scattering (D‐SERS) platform integrating multiscale nanoparticle geometry, quantum dot coupling, surface‐energy programming, and a multilayer perceptron model for AI‐assisted classification. It enables ultrahigh sensitivity, noninvasive detection, and specific Helicobacter pylori identification.
Ming‐Chang Lu, Chia‐Jung Lee, Chih‐Yuan Yao, Bo‐Ying Wu, Chih‐Wei Chiu   +4 more
wiley   +1 more source

Gastroesophageal reflux-induced cough: the positive feedback loop of microaspiration and neurogenic inflammation. [PDF]

Ther Adv Respir Dis
Rui Y, Yi F, Lin MT, Lu H, Chen Y, Zhu H, Chen Z, Shen B.   +7 more
europepmc   +1 more source

Fragment Coverage: Unified Visualization and Quantitative Assessment of MS/MS Fragmentation Supports Metabolite Identification in Macromolecule Drug Metabolism Studies

Rapid Communications in Mass Spectrometry, Volume 40, Issue 21, 15 November 2026.
ABSTRACT Rationale Peptides and oligonucleotides are increasingly used as therapeutic agents, making the identification and structural elucidation of their metabolites a critical step in drug development. Liquid chromatography–mass spectrometry (LC‐MS/MS) is the primary analytical technique for this purpose; however, extensive backbone fragmentation ...
Paula Cifuentes, Albert Garriga, Fabien Fontaine, Ismael Zamora   +3 more
wiley   +1 more source

Gatherings in Esophagology: Innovations and Future Directions in the Diagnosis and Management of Reflux Disease. [PDF]

Ann N Y Acad Sci
Cable J, Giuli R, Fox MR, Rosen RL, Valdovinos-García LR, Siboni S, Clarke JO, Johnston N, Samuels TL, Scarpignato C, Stein EM, Fass R, Remes-Troche JM, Khan A, Rahman AK, Lynch K, Jodorkovsky D, Vela MF, Vandenberg A, Kuo B, Ergun P, Jirapinyo P, Asti E, Tolone S, Sheu EG, Salvador R, Sozzi M, Husain IA, Wu JC, Hobson A, Sharma NS, Lo WK, Duncan DR, Gyawali CP, Chan WW, Sifrim D, Savarino E, de Bortoli N, Rogers BD.   +38 more
europepmc   +1 more source