Results 11 to 20 of about 21,364,758 (210)

Pepsinogen I, pepsinogen II, gastrin-17, and Helicobacter pylori serological biomarkers in the diagnosis of precursor lesions of gastric cancer [PDF]

Archives of Medical Science
Introduction Atrophic gastritis and intestinal metaplasia are precursor lesions of gastric cancer. The aim of this study was to determine the usefulness of the biomarkers pepsinogen I(PgI), pepsinogen II (PgII), gastrin-17, and H.
Josefina Yoaly Sánchez-López, Luis Carlos Díaz-Herrera, Lourdes del Carmen Rizo-de la Torre   +2 more
doaj   +3 more sources

Low Pepsinogen I Level Predicts Multiple Gastric Epithelial Neoplasias for Endoscopic Resection [PDF]

Gut and Liver, 2014
Background/AimsSynchronous/metachronous gastric epithelial neoplasias (GENs) in the remaining lesion can develop at sites other than the site of endoscopic resection.
Park SY, Lim SO, Ki HS, Jun CH, Park CH, Kim HS, Choi SK, Rew JS.   +7 more
doaj   +3 more sources

Longitudinal Changes in the Serum Pepsinogen I/II Ratio With Progression of Gastric Atrophy [PDF]

Journal of Clinical Laboratory Analysis, Volume 40, Issue 13, July 2026.
Serum pepsinogen (PG) I/II ratio decreased with progression of gastric mucosal atrophy and showed consistent intra‐individual changes over time. In a large cohort with repeated endoscopic evaluations, longitudinal declines in the PG I/II ratio paralleled worsening atrophic stages.
Soie Chung, Jung Kim, Ji Hyun Song, Jooyoung Lee, Sun Young Yang, Eun Young Song   +5 more
wiley   +2 more sources

Correlation between Interleukin-17, High Sensitivity C-Reactive Protein and Pepsinogen in Helicobacter pylori Infected Gastritis

Gastroenterology Insights
Gastritis is an inflammatory process in the gastric mucosa and submucosa caused by Helicobacter pylori (H. pylori). The infection modulates immune components, such as interleukin (IL) 17, high sensitivity C-reactive protein (hsCRP) and pepsinogen.
Jeanne Winarta, Bradley Jimmy Waleleng, Nelly Tandean Wenas, Fujiyanto, Oscar Miguna, Marco Rahardja   +5 more
doaj   +2 more sources

The impact of washed microbiota transplantation on serum gastric function markers: pepsinogen I, pepsinogen II, and Gastrin-17 [PDF]

Frontiers in Nutrition
Background and aimsConventional treatment methods for gastric diseases have problems such as drug resistance and recurrence. This study aims to explore whether a new treatment method—Washed Microbiota Transplantation (WMT)—can improve gastric mucosal ...
Youlin Song, Youlin Song, Guoqian Liu, Guoqian Liu, Juan Yang, Juan Yang, Jiangyan Wang, Jiangyan Wang, Shuo Feng, Shuo Feng, Shenghua Lu, Shenghua Lu, Zhichu Qin, Xingxiang He, Xingxiang He, Lei Wu, Lei Wu   +16 more
doaj   +2 more sources

Exploring the High‐Risk Factors of Gastric “Inflammatory Cancer Transformation” Based on Inflammatory Immune Response: Construction of RHPI Complicated With CAG Risk Prediction Model [PDF]

Cancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Objective To investigate risk factors for refractory Helicobacter pylori infection (RHPI) complicated by chronic atrophic gastritis (CAG) and to develop a risk prediction model for early identification of high‐risk patients. Methods A retrospective cohort study enrolled 367 RHPI patients from January 2015 to December 2024.
Tian‐tong Jiang, Liu‐feng Yi, Ya‐xuan Wang, Shao‐li Wang, Yan‐Jiao Zhang, Zhi‐hua Tian, Xin‐qiao Chu, Jing‐yu Chen, Yi Luo, Nan Luo, Zhen Liu   +10 more
wiley   +2 more sources

Differential impacts of Helicobacter pylori antibody typing on gastric secretory function: a cross-sectional study based on serum biomarkers [PDF]

BMC Gastroenterology
Objective Although gastric secretory dysfunction is common in H.pylori-associated gastropathy, the precise mechanisms underlying these functional alterations across different H.pylori antibody subtypes remain incompletely elucidated. This cross-sectional
Hongyuan Xu, Chenliu Zhu, Yang Yang, Xueping Zhao, Xiaotian Chen, Guangshi Zhong, Xue Liang, Chengning Yang   +7 more
doaj   +2 more sources

Efficacy and safety of oral Chinese patent medicine combined with quadruple therapy for chronic atrophic gastritis: a systematic review and network meta-analysis [PDF]

Frontiers in Medicine
BackgroundChronic atrophic gastritis (CAG) is an important precancerous lesion of gastric cancer, with Helicobacter pylori (H. pylori) infection being a major etiological factor. Although quadruple therapy is the first-line treatment for H.
Dan Han, Yang Yu, Bo-yi Wang, Zhan-ze Ma
doaj   +2 more sources

Serum gastrin 17, pepsinogen I and pepsinogen II in atrophic gastritis patients living in North-East of Iran [PDF]

Journal of Research in Medical Sciences, 2013
Background : Gastric carcinoma is the second most common cause of cancer-related death in Iran. It is well-known that atrophic gastritis is a major risk factor for gastric cancer, which leads to variations in the serum levels of gastrin 17 (G-17 ...
Mosalreza Hosseini, Sakineh Amoueian, Armin Attaranzadeh, Mehdi Montazer, Ghodratollah Soltani, Khairollah Asadollahi, Ghobad Abangah   +6 more
doaj   +2 more sources

Regional variations in serum pepsinogen levels and their influencing factors: a multi-center cross-sectional study [PDF]

Scientific Reports
Serum pepsinogen (PG) levels are recognized biomarkers influenced by various factors, including lifestyle, Helicobacter pylori (H. pylori) infection status, and the presence of gastric mucosal lesions.
Huang Jiaojiao, Yu Jiaying, Tong Yuling
doaj   +2 more sources