Association of serum pepsinogens and gastrin-17 with Helicobacter pylori infection assessed by urea breath test [PDF]
Frontiers in Cellular and Infection Microbiology, 2022 BackgroundAssociation of gastric atrophy or cancer with levels of serum pepsinogens, gastrin-17 and anti-Helicobacter pylori IgG antibody have been extensively studied. However, the association of serum pepsinogen and gastrin-17 with H.
Jun-peng Zhou +15 more
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Association of Serum Pepsinogens With Esophageal Squamous Cell Carcinoma Risk: A Systematic Review and Meta-Analysis [PDF]
Frontiers in Oncology, 2022 BackgroundSerum pepsinogens are serological biomarkers of gastric atrophy, and the latter is a risk factor for esophageal squamous cell carcinoma (ESCC). However, the association of serum pepsinogens with ESCC risk remains unclear. This systematic review
Zhen-Xiao Yang +8 more
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Serum Pepsinogens Combined with New Biomarkers Testing Using Chemiluminescent Enzyme Immunoassay for Non-Invasive Diagnosis of Atrophic Gastritis: A Prospective, Multicenter Study [PDF]
Diagnostics, 2022 Background: Analysis of serum biomarkers for the assessment of atrophic gastritis (AG), a gastric precancerous lesion, is of growing interest for identification of patients at increased risk of gastric cancer.
Nicolas Chapelle +14 more
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The Role of Serum Pepsinogen Tests for Detecting Gastric Cancer Between Sexes and Among Age Groups [PDF]
Gut and LiverGastric cancer (GC) remains a significant concern worldwide, with a very high incidence in Japan, South Korea, and China. Early diagnosis of GC is important for reducing its mortality; to achieve this, screening of individuals at a high risk for ...
Seon Hee Lim, Yonghoon Choi, Nayoung Kim
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The Impact of Acid‐Free Reflux on Vocal Cord Granuloma [PDF]
Laryngoscope Investigative OtolaryngologyObjectives To examine the types and characteristics of acid‐free reflux in vocal cord granuloma (VCG). Methods A retrospective analysis was conducted on the VCG patients and those with benign unilateral vocal cord lesions between October 2017 and January
Xiao‐Hong Liu +7 more
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Assessment of Serum Pepsinogens with and without Co-Testing with Gastrin-17 in Gastric Cancer Risk Assessment—Results from the GISTAR Pilot Study [PDF]
Diagnostics, 2022 Introduction––Serum pepsinogen tests for gastric cancer screening have been debated for decades. We assessed the performance of two pepsinogen assays with or without gastrin-17 for the detection of different precancerous lesions alone or as a composite ...
Claudia Robles +15 more
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Diagnostic performances of pepsinogens and gastrin-17 for atrophic gastritis and gastric cancer in Mongolian subjects. [PDF]
PLoS ONE, 2022 In Mongolia, gastric cancer morbidity and mortality are high, and more than 80 percent of cases are diagnosed at an advanced stage. This study aimed to evaluate pepsinogens (PGIs) and gastrin-17 (G-17) levels and to determine the diagnostic performances ...
Ganchimeg Dondov +10 more
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Molecular evolution of aspartic protease gene family in vertebrates [PDF]
Scientific ReportsAspartic proteases are a gene superfamily with diverse functions in vertebrates, including pepsinogens (Pgs), the precursors of the major gastric enzyme pepsin. Despite their physiological importance, the evolutionary history of this gene family has been
Tatsuki Nagasawa, Tomofumi Inokuchi
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Pepsinogen Assay Findings in Individuals With Gastric Atrophy and Intestinal Metaplasia [PDF]
The Korean Journal of Helicobacter and Upper Gastrointestinal ResearchSerum pepsinogen (PG) testing is widely used as a non-invasive biomarker for gastric atrophy; however, its clinical interpretation varies depending on the severity and distribution of gastritis as well as on the assay methods.
Sun-Young Lee
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The Most Recent Insights into the Roots of Gastric Cancer [PDF]
LifeHelicobacter pylori (H. pylori) is the most common bacterial infection worldwide, usually being acquired during childhood, and its persistence into adulthood represents one of the main contributors of gastric carcinogenesis. Based on these statements, it
Lorena Elena Meliț +2 more
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