Association of Serum Pepsinogens With Esophageal Squamous Cell Carcinoma Risk: A Systematic Review and Meta-Analysis [PDF]
Frontiers in Oncology, 2022 BackgroundSerum pepsinogens are serological biomarkers of gastric atrophy, and the latter is a risk factor for esophageal squamous cell carcinoma (ESCC). However, the association of serum pepsinogens with ESCC risk remains unclear. This systematic review
Wenjing Zhao
exaly +4 more sources
Association of serum pepsinogens and gastrin-17 with Helicobacter pylori infection assessed by urea breath test [PDF]
Frontiers in Cellular and Infection Microbiology, 2022 BackgroundAssociation of gastric atrophy or cancer with levels of serum pepsinogens, gastrin-17 and anti-Helicobacter pylori IgG antibody have been extensively studied. However, the association of serum pepsinogen and gastrin-17 with H.
Jun-peng Zhou +15 more
doaj +2 more sources
Assessment of Serum Pepsinogens with and without Co-Testing with Gastrin-17 in Gastric Cancer Risk Assessment—Results from the GISTAR Pilot Study [PDF]
Diagnostics, 2022 Introduction––Serum pepsinogen tests for gastric cancer screening have been debated for decades. We assessed the performance of two pepsinogen assays with or without gastrin-17 for the detection of different precancerous lesions alone or as a composite ...
Claudia Robles +15 more
doaj +2 more sources
Serum pepsinogens as a gastric cancer and gastritis biomarker in South and Southeast Asian populations. [PDF]
PLoS ONE, 2020 Serum pepsinogens have been widely acknowledged as gastric mucosal biomarkers; however, a multicountry report on the benefits of pepsinogens as biomarkers has not yet been published.
Muhammad Miftahussurur +13 more
doaj +2 more sources
Serum Pepsinogens Combined with New Biomarkers Testing Using Chemiluminescent Enzyme Immunoassay for Non-Invasive Diagnosis of Atrophic Gastritis: A Prospective, Multicenter Study [PDF]
Diagnostics, 2022 Background: Analysis of serum biomarkers for the assessment of atrophic gastritis (AG), a gastric precancerous lesion, is of growing interest for identification of patients at increased risk of gastric cancer.
Nicolas Chapelle +14 more
doaj +2 more sources
Helicobacter pylori infection, serum pepsinogens as markers of atrophic gastritis, and leukocyte telomere length: a population-based study [PDF]
Human Genomics, 2019 Background Persistent infections that induce prolonged inflammation might negatively affect the leukocyte telomere length (LTL); however, the role in LTL of Helicobacter pylori (H.
Khitam Muhsen +5 more
doaj +2 more sources
Significance of Serum Pepsinogens as a Biomarker for Gastric Cancer and Atrophic Gastritis Screening: A Systematic Review and Meta-Analysis. [PDF]
PLoS ONE, 2015 BackgroundHuman pepsinogens are considered promising serological biomarkers for the screening of atrophic gastritis (AG) and gastric cancer (GC). However, there has been controversy in the literature with respect to the validity of serum pepsinogen (SPG)
Ya-kai Huang +6 more
doaj +2 more sources
The Role of Serum Pepsinogen Tests for Detecting Gastric Cancer Between Sexes and Among Age Groups [PDF]
Gut and LiverGastric cancer (GC) remains a significant concern worldwide, with a very high incidence in Japan, South Korea, and China. Early diagnosis of GC is important for reducing its mortality; to achieve this, screening of individuals at a high risk for ...
Seon Hee Lim, Yonghoon Choi, Nayoung Kim
doaj +2 more sources
Serum pepsinogens and risk of esophageal squamous dysplasia. [PDF]
Int J Cancer, 2009 AbstractPepsinogens are a class of endopeptidases that are secreted by the gastric epithelium and released into the circulation. Low serum pepsinogen I (PGI) and low serum pepsinogen I/pepsinogen II ratio (PGI/II ratio) are markers of gastric fundic atrophy, and have recently been shown to be associated with increased risk of esophageal squamous cell ...
Kamangar F +10 more
europepmc +4 more sources
Monitoring the follow-up of autoimmune chronic atrophic gastritis using parietal cell antibodies and markers of gastric function [PDF]
Journal of Translational AutoimmunityIncreased interest in the pathogenesis and the evolution of autoimmune chronic atrophic gastritis (A-CAG) has led to the search for serological markers that can be used to detect changes in the gastric mucosa at an early stage and to monitor the course ...
Maria Piera Panozzo +2 more
doaj +2 more sources