Results 11 to 20 of about 1,324 (208)

Serum pepsinogens as a gastric cancer and gastritis biomarker in South and Southeast Asian populations. [PDF]

open access: yesPLoS ONE, 2020
Serum pepsinogens have been widely acknowledged as gastric mucosal biomarkers; however, a multicountry report on the benefits of pepsinogens as biomarkers has not yet been published.
Muhammad Miftahussurur   +13 more
doaj   +2 more sources

Pepsinogens in health and disease.

open access: yesCritical Reviews in Clinical Laboratory Sciences, 1993
Pepsinogens, precursors of pepsins (potent and abundant digestive enzymes that are the primary products of the gastric chief cells), are members of the family of aspartic proteases.
PLEBANI, MARIO
core   +4 more sources

Relationship Between Helicobacter pylori IgG Seroprevalence and the Immune Response to Poliovirus Vaccine Among School-Age Children From a Population With Near-Universal Immunity Level [PDF]

open access: yesFrontiers in Medicine, 2022
ObjectivesTo examine the association between Helicobacter pylori seroprevalence and serum pepsinogens (PGs) as markers of gastric inflammation), with high neutralizing antibody titers to poliovirus type 1 and 3 vaccine strains among children age 3–4 ...
Layaly Badran Abu Zher   +5 more
doaj   +2 more sources

Monitoring the follow-up of autoimmune chronic atrophic gastritis using parietal cell antibodies and markers of gastric function [PDF]

open access: yesJournal of Translational Autoimmunity
Increased interest in the pathogenesis and the evolution of autoimmune chronic atrophic gastritis (A-CAG) has led to the search for serological markers that can be used to detect changes in the gastric mucosa at an early stage and to monitor the course ...
Maria Piera Panozzo   +2 more
doaj   +2 more sources

Potential diagnostic, prognostic, and predictive biomarkers of gastric cancer [PDF]

open access: yesHealth Science Reports
Background Gastric cancer (GC), a malignant epithelial tumor, is the fourth leading cause of cancer‐related death worldwide. Therapeutic strategies for GC, despite the biggest challenges, can significantly improve survival rates through early detection ...
Ousman Mohammed   +2 more
doaj   +2 more sources

Activation of human pepsinogens [PDF]

open access: yesFEBS Letters, 1988
Human pepsinogen A3 and A5 have been purified to chromatographic and electrophoretic homogeneity. At pH 2 pepsinogen A3 activates at a much faster rate than pepsinogen A5. Leu-23 — Lys-24 is the first bond cleaved during activation of pepsinogen A3. This
B. Foltmann, Foltmann, B.
core   +3 more sources

Serum Assay Findings after Successful Helicobacter pylori Eradication [PDF]

open access: yesThe Korean Journal of Helicobacter and Upper Gastrointestinal Research, 2021
Serum pepsinogen (PG), anti-Helicobacter pylori (H. pylori) immunoglobulin G (IgG), and gastrin-17 (G-17) are plasma biomarkers for gastritis. H. pylori serology titers and PG levels increase during active H.
Sun-Young Lee
doaj   +1 more source

Helicobacter pylori infection and serum pepsinogen concentrations in an elderly population representative of Costa Rica

open access: yesPoblación y Salud en Mesoamérica, 2022
INTRODUCTION: Costa Rica has among the highest mortality rates from gastric cancer in the world, largely due to late detection. It is therefore important that economically and logistically sustainable screening is implemented in order to detect risk of ...
Clas Une   +4 more
doaj   +3 more sources

Serum pepsinogen level as a biomarker for atrophy, reflux esophagitis, and gastric cancer screening in Indonesia

open access: yesJournal of Research in Medical Sciences, 2022
Background: Chronic dyspepsia's symptoms are frequently seen in primary to tertiary healthcare in Indonesia. This study aimed to describe the potential usability of pepsinogen (PG) values in determining gastric mucosal conditions, including superficial ...
Muhammad Miftahussurur   +25 more
doaj   +1 more source

Clinical correlation between serum pepsinogen level and gastric atrophy in gastric neoplasm [PDF]

open access: yesThe Korean Journal of Internal Medicine, 2020
Background/Aims The relationship between the serum pepsinogen (sPG) level and changes in gastric mucosa has been well studied. Here, we evaluated the usefulness of sPG (I, II, I/II ratio) and intragastric pH as a biomarker of severe gastric atrophy in ...
Jae Hwang Cha, Jin Seok Jang
doaj   +1 more source

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