Serum pepsinogens as a gastric cancer and gastritis biomarker in South and Southeast Asian populations. [PDF]
Serum pepsinogens have been widely acknowledged as gastric mucosal biomarkers; however, a multicountry report on the benefits of pepsinogens as biomarkers has not yet been published.
Muhammad Miftahussurur +13 more
doaj +2 more sources
Pepsinogens in health and disease.
Pepsinogens, precursors of pepsins (potent and abundant digestive enzymes that are the primary products of the gastric chief cells), are members of the family of aspartic proteases.
PLEBANI, MARIO
core +4 more sources
Relationship Between Helicobacter pylori IgG Seroprevalence and the Immune Response to Poliovirus Vaccine Among School-Age Children From a Population With Near-Universal Immunity Level [PDF]
ObjectivesTo examine the association between Helicobacter pylori seroprevalence and serum pepsinogens (PGs) as markers of gastric inflammation), with high neutralizing antibody titers to poliovirus type 1 and 3 vaccine strains among children age 3–4 ...
Layaly Badran Abu Zher +5 more
doaj +2 more sources
Monitoring the follow-up of autoimmune chronic atrophic gastritis using parietal cell antibodies and markers of gastric function [PDF]
Increased interest in the pathogenesis and the evolution of autoimmune chronic atrophic gastritis (A-CAG) has led to the search for serological markers that can be used to detect changes in the gastric mucosa at an early stage and to monitor the course ...
Maria Piera Panozzo +2 more
doaj +2 more sources
Potential diagnostic, prognostic, and predictive biomarkers of gastric cancer [PDF]
Background Gastric cancer (GC), a malignant epithelial tumor, is the fourth leading cause of cancer‐related death worldwide. Therapeutic strategies for GC, despite the biggest challenges, can significantly improve survival rates through early detection ...
Ousman Mohammed +2 more
doaj +2 more sources
Activation of human pepsinogens [PDF]
Human pepsinogen A3 and A5 have been purified to chromatographic and electrophoretic homogeneity. At pH 2 pepsinogen A3 activates at a much faster rate than pepsinogen A5. Leu-23 — Lys-24 is the first bond cleaved during activation of pepsinogen A3. This
B. Foltmann, Foltmann, B.
core +3 more sources
Serum Assay Findings after Successful Helicobacter pylori Eradication [PDF]
Serum pepsinogen (PG), anti-Helicobacter pylori (H. pylori) immunoglobulin G (IgG), and gastrin-17 (G-17) are plasma biomarkers for gastritis. H. pylori serology titers and PG levels increase during active H.
Sun-Young Lee
doaj +1 more source
INTRODUCTION: Costa Rica has among the highest mortality rates from gastric cancer in the world, largely due to late detection. It is therefore important that economically and logistically sustainable screening is implemented in order to detect risk of ...
Clas Une +4 more
doaj +3 more sources
Background: Chronic dyspepsia's symptoms are frequently seen in primary to tertiary healthcare in Indonesia. This study aimed to describe the potential usability of pepsinogen (PG) values in determining gastric mucosal conditions, including superficial ...
Muhammad Miftahussurur +25 more
doaj +1 more source
Clinical correlation between serum pepsinogen level and gastric atrophy in gastric neoplasm [PDF]
Background/Aims The relationship between the serum pepsinogen (sPG) level and changes in gastric mucosa has been well studied. Here, we evaluated the usefulness of sPG (I, II, I/II ratio) and intragastric pH as a biomarker of severe gastric atrophy in ...
Jae Hwang Cha, Jin Seok Jang
doaj +1 more source

