Longitudinal Changes in the Serum Pepsinogen I/II Ratio With Progression of Gastric Atrophy. [PDF]
J Clin Lab AnalSerum pepsinogen (PG) I/II ratio decreased with progression of gastric mucosal atrophy and showed consistent intra‐individual changes over time. In a large cohort with repeated endoscopic evaluations, longitudinal declines in the PG I/II ratio paralleled worsening atrophic stages.
Chung S +5 more
europepmc +2 more sources
Exploring the High-Risk Factors of Gastric "Inflammatory Cancer Transformation" Based on Inflammatory Immune Response: Construction of RHPI Complicated With CAG Risk Prediction Model. [PDF]
Cancer MedABSTRACT Objective To investigate risk factors for refractory Helicobacter pylori infection (RHPI) complicated by chronic atrophic gastritis (CAG) and to develop a risk prediction model for early identification of high‐risk patients. Methods A retrospective cohort study enrolled 367 RHPI patients from January 2015 to December 2024.
Jiang TT +10 more
europepmc +2 more sources
The Impact of Acid‐Free Reflux on Vocal Cord Granuloma [PDF]
Laryngoscope Investigative OtolaryngologyObjectives To examine the types and characteristics of acid‐free reflux in vocal cord granuloma (VCG). Methods A retrospective analysis was conducted on the VCG patients and those with benign unilateral vocal cord lesions between October 2017 and January
Xiao‐Hong Liu +7 more
doaj +2 more sources
Changes in Pepsinogen Activity in Biological Fluids of Pregnant Women with Newborns of Different Weights [PDF]
BiomedicinesBackground: The main “peptic” cells of the gastric glands provide the body’s only source of pepsinogen synthesis and incretion. Small amounts of endogenously supplied pepsinogen in biological fluids play an important role in anabolic processes in the ...
Elena Kolodkina +2 more
doaj +2 more sources
Biomolecular Concepts, 2019 We aimed to determine optimal cut-off points of plasma levels of ghrelin and serum levels of pepsinogen I, II, and their ratio for screening of gastric cancer (GC).
Farahnaz Joukar +2 more
exaly +2 more sources
The role of serum trimethylamine n-oxide and lipopolysaccharide levels in the pathogenesis of chronic gastritis infected with Helicobacter pylori [PDF]
BMC GastroenterologyBackground Helicobacter pylori (HP) infection can cause chronic, intense inflammation of the gastric mucosa, which can lead to stomach cancer. Trimethylamine N-oxide (TMAO) is a dietary metabolite that increases HP virulence and inflammatory process.
Ugur Kaplankaya +9 more
doaj +2 more sources
An investigation of Helicobacter pylori infection and potential risk factors of colonization found in 10 661 cases from routine physical examination [PDF]
Jichu yixue yu linchuang, 2022 Objective To investigate the situation of Helicobacter pylori(H.pylori) infection in healthy people and analyze the related risk factors. Methods Retrospective analysis was conducted on 10 661 healthy subjects who underwent carbon 13-urea breath test ...
LEI Rong, YANG Dan, YUAN Fang-tao, ZHOU Xiao-yan, JIANG Yi-min, LIU Mi
doaj +1 more source
Analysis of high risk factors for chronic atrophic gastritis
The Saudi Journal of Gastroenterology, 2023 Background: Screening for chronic atrophic gastritis (CAG) is crucial for the prevention and early detection of gastric cancer. Endoscopy is the main method of CAG diagnosis, with high training requirements and limited accuracy, making it difficult to ...
Xian-Ke Lin, Wei-Lin Wang
doaj +1 more source
Correction: Diagnostic value of combined detection of pepsinogen, gastrin-17, and 13C-urea breath test in Helicobacter pylori-associated chronic gastritis in children: a multivariate analysis [PDF]
Frontiers in PediatricsYiyun Gao +4 more
doaj +2 more sources
SERUM PEPSINOGEN I AND PEPSINOGEN II AS NON-INVASIVE BIOMARKERS FOR THE DIAGNOSIS OF CHRONIC ATROPHIC GASTRITIS [PDF]
Journal of IMAB, 2022 Atrophic gastritis, intestinal metaplasia and dysplasia of the gastric mucosa are major risk factors for the development of an intestinal type of gastric cancer.
Zornica Gorcheva +2 more
doaj +1 more source