Results 31 to 40 of about 28,627 (213)
Rearranging the domains of pepsinogen [PDF]
Protein Science, 1995 AbstractMost eukaryotic aspartic protease zymogens are synthesized as a single polypeptide chain that contains two distinct homologous lobes and a pro peptide, which is removed upon activation. In pepsinogen, the pro peptide precedes the N‐terminal lobe (designated pep) and the C‐terminal lobe (designated sin).
X, Lin, G, Koelsch, J A, Loy, J, Tang
openaire +2 more sources
Helicobacter pylori infection appears essential for stomach carcinogenesis: Observations in Semarang, Indonesia [PDF]
, 2005 The gastric cancer incidence in Semarang, Indonesia, is exceedingly low: only approximately 1/100th of the level in Japan. To elucidate the reason, we carried out an ecological study recruiting 69 male and 102 female participants from the general ...
Wijaya, Indra +11 more
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Diagnostics, 2022 The accuracy of plasma pepsinogen (Pg) as a marker for precancerous gastric lesions (PGL) has shown variable results. We aimed to identify factors associated with false negative (FN) cases in Pg testing and to adjust cut-off values for these factors in ...
Danute Razuka-Ebela +10 more
doaj +1 more source
Combination of gastric atrophy, reflux symptoms and histological subtype indicates two distinct aetiologies of gatric cardia cancer. [PDF]
, 2008 <b>INTRODUCTION</b> Atrophic gastritis is a risk factor for non-cardia gastric cancer, and gastro-oesophageal reflux disease (GORD) for oesophageal adenocarcinoma.
Didevar, R. +11 more
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Gastroenterology Research and Practice, 2018 Objective. The serum pepsinogen test has limitation in its predictive power as a noninvasive biomarker for gastric cancer screening. We aimed to investigate whether the combination of TFF3 and pepsinogen could be an effective biomarker for the detection ...
Hyun Seok Lee +9 more
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Clinical Significance of Pepsinogen C Tumor Expression in Patients with Stage D2 Prostate Carcinoma
The International Journal of Biological Markers, 2002 Pepsinogen C is an aspartyl protease mainly involved in the digestion of proteins in the stomach, and an androgen-inducible protein in breast cancer cells. The aims of this study were to evaluate the expression and clinical significance of this enzyme in
M. Díaz +6 more
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Development of a Radioimmunoassay for Bovine Pepsinogen A
Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 2005 Pepsinogen A is the most abundant zymogen found in blood, and its enzymatic measurement is used for the diagnosis of gastric lesions. The present study was conducted to develop a radioimmunoassay (RIA) specific to pepsinogen A in bovine plasma.
D. I. Sidikou, B. Remy, J. F. Beckers
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Gastroenterology Research and Practice, 2011 Aim. Chronic gastritis was assessed serologically, endoscopically and histologically to identify correlations between these methods. Methods. Subjects comprised 319 patients who had provided informed consent.
Toshitatsu Takao +17 more
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Бюллетень сибирской медицины, 2012 The pepsinogenemia level is examined as a risk factor of atrophy and inflammation activity in gastroduodenal region mucous region in 20 patients with erosive and ulcerous changes this localization as before as after operations with cardiopulmonary bypass.
Ye. A. Sorokina +5 more
doaj +1 more source
iMeta, EarlyView.The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li +29 more
wiley +1 more source