Results 1 to 10 of about 216 (135)

Gastrin-17 Levels in Pre-malignancy Gastritis Lesions [PDF]

European Medical Journal Gastroenterology, 2022
Background: Gastritis is an inflammatory process on the lining of the stomach that could be caused by various factors. Untreated inflammatory processes could lead to ulcers. Gastrin hormone is released by gastrin-secreting enteroendocrine cells (G cells)
Sahat Halim, Gontar Alamnsyah Siregar
doaj   +2 more sources

Analysis of gastrin‐17 and its related influencing factors in physical examination results

Immunity, Inflammation and Disease, 2023
Background To analyze the difference of serum gastrin‐17 (G17) level in healthy people with different sex, age, and body mass index (BMI), to explore the correlation between G17 and pepsinogen, and to study the influences of Helicobacter pylori (H ...
Junchao Zeng, Yan Shen, Sanping Xu, Rui Yang   +3 more
doaj   +3 more sources

A Prospective Study on the Detection of Gastric Neoplasms Using Pepsinogen and Gastrin-17 Levels

Gut and Liver
Background/Aims : GastroPanel tests include gastrin-17 (G-17) levels in addition to pepsinogen (PG) and Helicobacter pylori serology tests. The aim of this study was to identify significant test findings in patients with gastric neoplasms by comparing ...
Sun-Young Lee, Hee-Won Moon, Yeon-Sun Ahn, Joo Hye Song, Jeong Hwan Kim, In-Kyung Sung   +5 more
doaj   +3 more sources

Association of serum pepsinogens and gastrin-17 with Helicobacter pylori infection assessed by urea breath test

Frontiers in Cellular and Infection Microbiology, 2022
BackgroundAssociation of gastric atrophy or cancer with levels of serum pepsinogens, gastrin-17 and anti-Helicobacter pylori IgG antibody have been extensively studied. However, the association of serum pepsinogen and gastrin-17 with H.
Jun-peng Zhou, Jun-peng Zhou, Chang-hai Liu, Chang-hai Liu, Bo-wen Liu, You-juan Wang, Mohammed Benghezal, Mohammed Benghezal, Barry James Marshall, Barry James Marshall, Barry James Marshall, Barry James Marshall, Hong Tang, Hong Tang, Hong Li, Hong Li   +15 more
doaj   +1 more source

The Production and Role of Gastrin-17 and Gastrin-17-Gly in Gastrointestinal Cancers [PDF]

Protein & Peptide Letters, 2009
The gastrointestinal peptide hormone gastrin is responsible for initiating the release of gastric acid in the stomach in response to the presence of food and/or humoral factors such as gastrin releasing peptide. However, it has a role in the growth and maintenance of the gastric epithelium, and has been implicated in the formation and growth of gastric
Jeffrey, Copps, Richard F, Murphy, Sándor, Lovas   +2 more
openaire   +2 more sources

Assessment of Serum Pepsinogens with and without Co-Testing with Gastrin-17 in Gastric Cancer Risk Assessment—Results from the GISTAR Pilot Study

Diagnostics, 2022
Introduction––Serum pepsinogen tests for gastric cancer screening have been debated for decades. We assessed the performance of two pepsinogen assays with or without gastrin-17 for the detection of different precancerous lesions alone or as a composite ...
Claudia Robles, Dace Rudzite, Inese Polaka, Olga Sjomina, Lilian Tzivian, Ilze Kikuste, Ivars Tolmanis, Aigars Vanags, Sergejs Isajevs, Inta Liepniece-Karele, Danute Razuka-Ebela, Sergej Parshutin, Raul Murillo, Rolando Herrero, Jin Young Park, Marcis Leja   +15 more
doaj   +1 more source

TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk

Hepatology, EarlyView., 2022
The systematic approach in elucidating the gain‐of‐function (GOF) roles of TP53 mutations in early liver carcinogenesis. Unique downstream targets of TP53 L3 mutations were identified from chormatin immunoprecipitation sequencing in HCC cell lines, followed by a series of validation assays to substantiate the exclusive transcriptional regulations ...
Yin Kau Lam, Jianqing Yu, Hao Huang, Xiaofan Ding, Alissa M. Wong, Howard H. Leung, Anthony W. Chan, Kelvin K. Ng, Mingjing Xu, Xin Wang, Nathalie Wong   +10 more
wiley   +1 more source

Bioactivity of analogs of the N-terminal region of gastrin-17 [PDF]

Peptides, 2009
Gastrin-17-Gly (G17-Gly) has been shown to bind to non-CCK nanomolar and micromolar affinity sites on DLD-1 and HT-29 human colonic carcinoma cells and to stimulate cellular proliferation. However, in previous studies, we showed that C-terminal truncation of the gastrin-17 (G17) to the G17 analog G17(1-12) and then to G17(1-6)-NH(2) did not remove the ...
Jeffrey, Copps, Shawn, Ahmed, Richard F, Murphy, Sándor, Lovas   +3 more
openaire   +2 more sources

Toll-Like Receptor 4 Wild Type Homozygozity of Polymorphisms +896 and +1196 Is Associated with High Gastrin Serum Levels and Peptic Ulcer Risk. [PDF]

PLoS ONE, 2015
Toll-like receptor 4 is a part of the innate immune system and recognizes Helicobacter pylori lipopolysaccharide. The goal of this study was to analyze the role of Toll-like receptor 4 polymorphisms +896 (rs4986790) and +1196 (rs4986791) in the ...
Vesa-Matti Pohjanen, Olli-Pekka Koivurova, Heikki Huhta, Olli Helminen, Johanna M Mäkinen, Jari M Karhukorpi, Tapio Joensuu, Pentti O Koistinen, Jarno M Valtonen, Seppo E Niemelä, Riitta A Karttunen, Tuomo J Karttunen   +11 more
doaj   +1 more source

Clinical value of serum pepsinogen,gastrin 17 and Helicobacter pylori IgG antibody in primary screening of gastric diseases [PDF]

Zhenduanxue lilun yu shijian, 2022
Objective: To explore the clinical value of serum PGI, PGII, PGI/PGII, G-17 levels and Hp-IgG antibody in the preliminary screening of gastric diseases. Methods: A total of 300 patients who underwent gastroscopy in the Gastroenterology Department of our ...
LI Nana, QI Tao, ZHU Liming
doaj   +1 more source