Results 161 to 170 of about 151,829 (286)

Responses to Ligand Binding in the Bacterial DNA Sliding Clamp “β‐Clamp” Manifest in Dynamic Allosteric Effects

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The homo‐dimeric, ring‐shaped bacterial DNA sliding clamp, β‐clamp, is a central hub in DNA replication and repair. It interacts with a plethora of proteins via their short linear motifs, binding to the same hydrophobic binding pocket on β‐clamp. Although the structure, functions, and interactions of β‐clamp have been amply studied, less focus
Signe Simonsen   +5 more
wiley   +1 more source

Peptic Dyspepsia

open access: yesInternational Journal of Clinical Practice, 1967
openaire   +2 more sources

Civilization and peptic ulcer* [PDF]

open access: yesInternational Journal of Epidemiology, 1962
Zena Stein, Mervyn Susser
openaire   +4 more sources

Cross‐Linking Mass Spectrometry of the Antimicrobial Peptides Magainin 2 and PGLa Reveals Heterodimerization in Micellar Medium

open access: yesRapid Communications in Mass Spectrometry, EarlyView.
ABSTRACT Rationale In this study, we applied cross‐linking mass spectrometry (XL‐MS) to characterize the oligomeric states of a PGLa/magainin 2 mixture and gain insight into the heterodimerization previously suggested in the literature. Both peptides have shown a synergistic enhancement of activity when tested in antimicrobial assays; however, the ...
Emilie Hirschler   +7 more
wiley   +1 more source

Porous Silicon Nanoparticle Hydrogel Formulation for Topical Delivery of Flightless I Neutralizing Antibody and Improved Diabetic Wound Healing

open access: yesSmall, EarlyView.
A biodegradable porous silicon nanoparticle (pSi NP) hydrogel formulation delivers a Flightless I neutralizing antibody (FnAb) topically to diabetic wounds. The formulation protects FnAb from proteolytic degradation and enables sustained 14‐day release, aligned with routine dressing changes.
Christopher T. Turner   +6 more
wiley   +1 more source

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