Results 61 to 70 of about 151,608 (341)

Role of dietary polyphenols in the management of peptic ulcer.

World Journal of Gastroenterology, 2015
Peptic ulcer disease is a multifactorial and complex disease involving gastric and duodenal ulcers. Despite medical advances, the management of peptic ulcer and its complications remains a challenge, with high morbidity and death rates for the disease ...
M. Farzaei, M. Abdollahi, R. Rahimi
semanticscholar   +1 more source

Protease‐Mediated Synthesis of Zein Nanofibrils: From Structural Elucidation to Functional Application

Advanced Science, EarlyView.
The globular shape and hydrophobicity of zein made it unsuitable to be processed in pure aqueous environment. Pepsin‐mediated hydrolysis converts zein into water‐soluble and fibril‐forming peptides with a bioconversion rate exceeding 70%, enabling the self‐assembly of amyloid‐like nanofibrils.
Mingqin Li, Tonghui Jin, Simone Wüthrich, Jiangtao Zhou, Qiyao Sun, Ting Li, Zhou Dong, Eva Maria Zunzuneigui Bru, Raffaele Mezzenga   +8 more
wiley   +1 more source

Antagonist Targeting the Species‐Specific Fatty Acid Dehydrogenase/Isomerase FabX for Anti‐H. pylori Infection

Advanced Science, EarlyView.
This study demonstrates that the atypical dehydrogenase/isomerase FabX in Type‐II fatty acid biosynthesis pathway is essential for H. pylori infection by retaining unsaturated fatty acid synthesis and producing superoxide (ROS). A small molecule FBX‐1991 that specifically targets FabX to inhibit H.
Lin Zhang, Xiaoxue Ruan, Xudong Hang, Ding Heng, Chang Cai, Liping Zeng, Guoxin Zhang, Lu Zhou, Hongkai Bi, Liang Zhang   +9 more
wiley   +1 more source

Peptic ulcer disease among dyspeptic patients at endoscopy unit, University of Gondar hospital, Northwest Ethiopia

BMC Gastroenterology, 2022
Background Dyspepsia is a common complaint in upper gastrointestinal disorders. It is described as predominant epigastric pain lasting for at least one month. Globally, peptic ulcer disease occurs in 3.5–32% of patients with dyspepsia.
Belete Assefa, Abilo Tadesse, Zenahebezu Abay, Alula Abebe, Tsebaot Tesfaye, Melaku Tadesse, Ayenew Molla   +6 more
doaj   +1 more source

Perceived stress as a risk factor for peptic ulcers: a register-based cohort study

BMC Gastroenterology, 2016
BackgroundThe association between stress and peptic ulcers has been questioned since the discovery of helicobacter pylori. This study examined whether high perceived everyday life stress was associated with an increased risk of either receiving a triple ...
Ulrik Deding, L. Ejlskov, Mads Phillip Kofoed Grabas, B. Nielsen, C. Torp-Pedersen, H. Bøggild   +5 more
semanticscholar   +1 more source

Eosinophils‐Induced Lumican Secretion by Synovial Fibroblasts Alleviates Cartilage Degradation via the TGF‐β Pathway Mediated by Anxa1 Binding

Advanced Science, EarlyView.
Eosinophils play a crucial role in the progression of temporomandibular joint osteoarthritis (TMJOA). This study demonstrates that eosinophils, induced by OVA/IL‐5, promote Lumican secretion in the synovium, which binds to Annexin A1 in chondrocytes, inhibiting transforming growth factor β2 and Smad2/3 phosphorylation.
Wenqian Chen, Yuwei Zhou, Wenxiu Yuan, Yanjing Ou, Hanyu Lin, Kaixun He, Xueshen Qian, Huachen Chen, Chengchaozi Wang, Jie Lu, Weiping Chen, Dexiong Li, Jiang Chen   +12 more
wiley   +1 more source

Initial Decisions for Peptic Ulcer Perforation [PDF]

Journal of Acute Care Surgery, 2015
Peptic ulcer perforation, despite anti-ulcer medication and Helicobacter pylori eradication, is still common in emergency surgery. Operative management includes primary repair, omental patch closure, vagotomy, and wedge resection. The choice of treatment
Jung-Min Bae
doaj   +1 more source

Profile of peptic ulcer disease and its risk factors in Arar, Northern Saudi Arabia

Electronic Physician, 2017
Background Peptic ulcer disease is a multifactorial health problem, and its prevalence and risk factors have changed considerably within the past century.
A. S. Albaqawi, N. el-Fetoh, R. F. Alanazi, N. Alanazi, S. Alrayya, A. Alanazi, S. T. Alenezi, Rehab Abdallah Alrkowi Alanazi, A. Alshalan, O. Alenezi, W. Ali   +10 more
semanticscholar   +1 more source

Engineered Probiotics Mitigate Gut Barrier Dysfunction Induced by Nanoplastics

Advanced Science, EarlyView.
Intestinal barrier stability is vital for gut health. Plastic polyethylene terephthalate (PET) disrupts this barrier, causing inflammation and infections. This study encodes transforming growth factor‐β into EcN and modifies its surface with pH‐responsive polymer (EcNT@L), creating an oral drug delivery system to repair nano PET‐induced intestinal ...
Wenxin Chen, Qiyan Guo, Hong Li, Xue Chi, Xiang Ma, Yanqiong Tang, Quanfeng Liang, Zhu Liu, Yong Liu, Juanjuan Li   +9 more
wiley   +1 more source

Depression is associated with increased disease activity in patients with ulcerative colitis: A propensity score‐matched analysis using a nationwide database in Japan

JGH Open, Volume 6, Issue 12, Page 876-885, December 2022., 2022
Depression might be associated with increased disease activity in patients with ulcerative colitis (UC), which could lead to a poor clinical course. It might be better to consider referring patients with UC who have depressive symptoms to a psychiatrist to improve their clinical course.
Hideaki Oyama, Rintaro Moroi, Kunio Tarasawa, Yusuke Shimoyama, Takeo Naito, Atsushi Sakuma, Hisashi Shiga, Yoichi Kakuta, Kiyohide Fushimi, Kenji Fujimori, Yoshitaka Kinouchi, Atsushi Masamune   +11 more
wiley   +1 more source