Results 121 to 130 of about 3,072 (176)

Exploring Risks of Adverse Drug Events From Single Drug to Three‐Drug Combination

open access: yesClinical and Translational Science, Volume 19, Issue 8, August 2026.
ABSTRACT Use of three‐drug combinations is common and could increase the risk of adverse drug events (ADEs). Signals of ADEs from three‐drug combinations could be identified from real‐world data, and the risks of ADEs from single drug exposure to three‐drug combination exposure could be illustrated by a graphic model.
Yi Shi   +14 more
wiley   +1 more source

Association Between SGLT2 Inhibitors and DPP‐4 Inhibitors Use and Risk of Acute Pancreatitis: Findings From Nationwide Case‐Based Analyses

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 6767-6775, August 2026.
ABSTRACT Aims The Korean national health insurance claims database was utilised to investigate the association between sodium–glucose cotransporter 2 inhibitors (SGLT2i) or dipeptidyl peptidase‐4 inhibitors (DPP‐4i) and the risk of acute pancreatitis (AP). Materials and Methods Patients with type 2 diabetes mellitus prescribed DPP‐4i or SGLT2i at least
Ye‐Jee Kim   +5 more
wiley   +1 more source

Nonsteroidal Anti‐Inflammatory Drugs and the Risk of Periodontitis Among Adults With Osteoarthritis: A Target Trial Emulation

open access: yesJournal of Clinical Periodontology, Volume 53, Issue 8, Page 1301-1311, August 2026.
ABSTRACT Background Nonsteroidal anti‐inflammatory drugs (NSAIDs) may mitigate periodontal tissue breakdown through cyclooxygenase (COX) inhibition; however, their long‐term effects on the risk of periodontitis remain unclear. Methods We emulated target trials using US electronic health records (1995–2019) to compare the 5‐year risk of incident ...
Ignacio Leiva‐Escobar   +7 more
wiley   +1 more source

PERFORATED PEPTIC ULCER

open access: yesAnnals of Surgery, 1941
R A, Griswold, R F, Antoncic
openaire   +3 more sources

Peptic ulcer disease

Lancet, The, 2017
The rapidly declining prevalence of Helicobacter pylori infection and widespread use of potent anti-secretory drugs means peptic ulcer disease has become substantially less prevalent than it was two decades ago. Management has, however, become more challenging than ever because of the threat of increasing antimicrobial resistance worldwide and ...

exaly   +3 more sources

Peptic ulcer

Medicina Clínica (English Edition), 2023
Peptic ulcer disease is a frequent pathology; although the incidence has decreased in recent years, it continues to be an important cause of morbidity and mortality associated with high healthcare costs. The most important risk factors are Helicobacter pylori(H. pylori) infection and the use of non-steroidal anti-inflammatory drugs.
Isabel, Laucirica   +2 more
openaire   +2 more sources

PEPTIC ULCER

The Lancet, 1975
Indigestion and heartburn have been described for thousands of years, but it was only in the 16th century that the disease peptic ulcer was established by autopsy. At first, only gastric ulcers were identified. In the 18th century, duodenal ulcers, most of which were fatal cases after perforation or hemorrhage, were seen.
openaire   +2 more sources

Peptic Ulcer in Childhood

Postgraduate Medicine, 1953
Peptic ulcer in childhood has been considered a relatively rare disease although sporadic reports of its occurrence have appeared. It has not usually been included in the differential diagnosis of conditions causing recurrent abdominal pain or vomiting in the pediatric patient.
openaire   +3 more sources

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