Results 131 to 140 of about 112,904 (357)

Reappraisal of non-invasive management strategies for uninvestigated dyspepsia: a cost-minimization analysis [PDF]

open access: yes, 2002
Background : The benefits of the Helicobacter pylori test-and-treat strategy are attributable largely to the cure of peptic ulcer disease while limiting the use of endoscopy.
A. M. Fendrick   +68 more
core   +2 more sources

Severe relapse after cessation of immunosuppressive therapy in a patient with co‐occurrence of neuromyelitis optica spectrum disorder and Sjögren's syndrome: A case report

open access: yesIbrain, EarlyView.
We report a girl with a diagnosis of “neuromyelitis optica spectrum disorder comorbid Sjogren's syndrome” whose condition showed significant improvement after treatment with corticosteroids and immunosuppressive drugs (prednisolone, hydroxychloroquine, and mycophenolate mofetil).
Man‐Min Zhu   +3 more
wiley   +1 more source

Trends in peptic ulcer disease and the identification of Helicobacter Pylori as a causative organism: Population-based estimates from the US nationwide inpatient sample

open access: yesJournal of Global Infectious Diseases, 2011
Background: Peptic ulcer disease can lead to serious complications including massive hemorrhage or bowel perforation. The modern treatment of peptic ulcer disease has transitioned from the control of gastric acid secretion to include antibiotic therapy ...
Bronislava Bashinskaya   +4 more
doaj   +1 more source

A Refined Deep Learning Architecture for Diabetic Foot Ulcers Detection [PDF]

open access: yesarXiv, 2020
Diabetic Foot Ulcers (DFU) that affect the lower extremities are a major complication of diabetes. Each year, more than 1 million diabetic patients undergo amputation due to failure to recognize DFU and get the proper treatment from clinicians. There is an urgent need to use a CAD system for the detection of DFU.
arxiv  

Helicobacter pylori virulence factors in duodenal ulceration: A primary cause or a secondary infection causing chronicity [PDF]

open access: yes, 2006
Reports from countries with a high prevalence of Helicobacter pylori. (H pylori) infection do not show a proportionately high prevalence of duodenal ulceration, suggesting the possibility that H pylori cannot be a primary cause of duodenal ulceration. It
Hobsley, M, Holton, J, Tovey, FI
core   +1 more source

40 years after the discovery of Helicobacter Pylori: Performing optimized “subtraction” for clinical eradication

open access: yesiMetaOmics, EarlyView.
It has been 40 years since the first discovery of the important human pathogen, Helicobacter pylori (H. pylori). Eradication of the infection continues to pose significant challenges in part because of the global increase in antibiotic resistance. Generally, the “addition” strategy has failed to deliver the desired results for more than a short period ...
Yi Hu   +14 more
wiley   +1 more source

Functional assessment of mitochondrial DNA 4977 bp deletion in peptic ulcer disease

open access: yesمجله دانشگاه علوم پزشکی بیرجند, 2014
Background and Aim: A peptic ulcer is a breach in the gastric or duodenal mucosa down to the submucosa. There is evidence concerning the role of Reactive Oxygen Species (ROS) in the genesis of such ulcers production of intracellular ROS along ...
Arezoo Haghighi   +3 more
doaj  

Recent advances in peptic ulcer bleeding [PDF]

open access: yes, 2009
Peptic ulcer bleeding remains a common cause of hospital admission, morbidity and mortality. Data published since 2006 illustrate that assessment, endoscopic and pharmacological management, and follow-up strategies can be refined to improve the overall ...
Beales, Ian LP
core   +2 more sources

Severe Impact of Omeprazole Timing on pH‐Sensitive Dasatinib Absorption: Unveiling Substantial Drug–Drug Interaction

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract The absorption and bioavailability of most tyrosine kinase inhibitors are affected by gastrointestinal pH as they are weak basic lipophilic drugs. Hence, concomitant use of acid reducing agents (ARAs) is frequently restricted. Particularly comedication of crystalline dasatinib (Sprycel) and proton‐pump inhibitors (PPIs) should be avoided. Drug–
Per Andersson   +4 more
wiley   +1 more source

Physiologically Based Pharmacokinetic Modeling and Simulation to Support a Change in the FDA‐Labeled Dosing Frequency of RHB‐105 Low‐Dose Rifabutin Triple Therapy for Helicobacter pylori Eradication

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Patient adherence is vital for Helicobacter pylori eradication. Simplifying therapy dosing schedules may promote patient adherence, enhance treatment success rates, and help mitigate the development of antibiotic resistance. We aimed to assess plasma and intragastric rifabutin, amoxicillin, and omeprazole concentrations comparing two dosing ...
Nimish Vakil   +6 more
wiley   +1 more source

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