pH‐Tunable Material Properties of Glycine‐Rich Condensates from Tick Bioadhesive
This work studies the influence of pH on the phase separation behavior of a disordered glycine‐rich protein found in tick bioadhesive. The results show profound impact on the propensity of coacervation, condensate microstructure and viscosity, amphiphilicity of the peptides, and effective encapsulation of therapeutic molecules.
Manali Nandy +5 more
wiley +1 more source
Maphumulo Siyabonga I. +2 more
doaj +1 more source
Self-assembling peptide nanofibers as growth factor-mimicking scaffolds enhancing the bone regeneration potential of nanoceramics: a triad of <i>in vitro</i>, <i>in vivo</i>, and clinical trial studies. [PDF]
Alahdad N +7 more
europepmc +1 more source
Peptide Sequencing With Single Acid Resolution Using a Sub‐Nanometer Diameter Pore
To sequence a single molecule of Aβ1−42–sodium dodecyl sulfate (SDS), the aggregate is forced through a sub‐nanopore 0.4 nm in diameter spanning a 4.0 nm thick membrane. The figure is a visual molecular dynamics (VMD) snapshot depicting the translocation of Aβ1−42–SDS through the pore; only the peptide, the SDS, the Na+ (yellow/green) and Cl− (cyan ...
Apurba Paul +8 more
wiley +1 more source
Pmt4 recognizes two separate acceptor sites to O-mannosylate in the S/T-rich regions of substrate proteins. [PDF]
Du M, Yuan Z, Kovach A, Lyu M, Li H.
europepmc +1 more source
This research presents a novel implantable bio‐battery, GF‐OsG, tailored for diabetic bone repair. GF‐OsG generates microcurrents in high‐glucose conditions to enhance vascularization, shift macrophages to the M2 phenotype, and regulate immune responses.
Nanning Lv +10 more
wiley +1 more source
Scoring information integration with statistical quality control enhanced cross-run analysis of data-independent acquisition proteomics data. [PDF]
Gao M, Gupta S, Yang W, Yu R, Röst HL.
europepmc +1 more source
Multifunctional Microstructured Surfaces by Microcontact Printing of Reactive Microgels
Reactive poly(N‐vinylcaprolactam‐co‐glycidyl methacrylate) microgels are used as functional inks to create surface‐grafted arrays on glass via microcontact printing. The patterns (10–50 µm widths and spacings) enable stable binding and post‐functionalization with dyes and peptides.
Inga Litzen +4 more
wiley +1 more source
Overcoming Oral Cavity Barriers for Peptide Delivery Using Advanced Pharmaceutical Techniques and Nano-Formulation Platforms. [PDF]
Amer AA, Bingle L, Elkordy AA, Chaw CS.
europepmc +1 more source
Tunable and Recyclable Piezoelectric Biomaterials via Ion‐Directed Guanine‐Quadruplex Assembly
Guanine‐quadruplex (GQ) assemblies, formed via ion‐mediated self‐assembly of amphiphilic guanine derivatives, are introduced as tunable and recyclable piezoelectric biomaterials. Distinct alkali ions induce unique dipole configurations and piezoelectric outputs, with K⁺ yielding the highest performance.
Seungho Lee +9 more
wiley +1 more source

