Nodal Expansion, Tumor Infiltration and Exhaustion of Neoepitope-Specific Th Cells After Prophylactic Peptide Vaccination and Anti-CTLA4 Therapy in Mouse Melanoma B16. [PDF]
Shabalkina AV+11 more
europepmc +1 more source
An RBC membrane camouflaged, cell‐penetrating peptides R8‐based drug delivery system is constructed to achieve a synergistic combination of natural compounds triptolide (TP) and celastrol (Cel), inducing tumor cell apoptosis, reducing tumor metastasis invasion and triggering autophagy disorder in breast cancer and liver cancer.
Qian Cheng+6 more
wiley +1 more source
AMCL: supervised contrastive learning with hard sample mining for multi-functional therapeutic peptide prediction. [PDF]
Fang J, Fan H, Zhao J, Zhao J, Xia J.
europepmc +1 more source
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee+9 more
wiley +1 more source
Functional characterization of a common XIa inhibitory Kunitz-domain Shp4 from nine schistosoma secreted proteins with diverse C-terminal fragments. [PDF]
Ye X+10 more
europepmc +1 more source
A Cyclized Helix-Loop-Helix Peptide as a Molecular Scaffold for Cell-Membrane Permeable Inhibitors for the Interaction Between Estrogen Receptor α and Coactivator SRC1. [PDF]
Fujiwara D+8 more
europepmc +1 more source
Deciphering the MHC immunopeptidome of human cancers with Ligand.MHC atlas. [PDF]
Ran Z+9 more
europepmc +1 more source
Surface keratin 1, a tumor-selective peptide target in human triple-negative breast cancer. [PDF]
Yao SJ+10 more
europepmc +1 more source
Learning with Privileged Knowledge Distillation for Improved Peptide-Protein Docking. [PDF]
Zhang Z+4 more
europepmc +1 more source