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Characterization of RufT Thioesterase Domain Reveals Insights into Rufomycin Cyclization and the Biosynthetic Origin of Rufomyazine. [PDF]
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The Quarterly Journal of Nuclear Medicine and Molecular Imaging, 2020
In recent years, the introduction of theranostic twins for specific diagnosis and treatment in patients with neuroendocrine tumors became a nuclear medicine success story. 64Cu/18F labeled prostate specific membrane antigen (PSMA) for molecular imaging with PET-CT and peptide radioligand therapy with 177Lu labeled PSMA inhibitors will favorably become ...
Siroos Mirzaei, R W Lipp
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In recent years, the introduction of theranostic twins for specific diagnosis and treatment in patients with neuroendocrine tumors became a nuclear medicine success story. 64Cu/18F labeled prostate specific membrane antigen (PSMA) for molecular imaging with PET-CT and peptide radioligand therapy with 177Lu labeled PSMA inhibitors will favorably become ...
Siroos Mirzaei, R W Lipp
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Self Peptides and the Peptidic Self
International Reviews of Immunology, 2001Twenty years ago, antigenic and self peptides presented by MHC molecules were absent from the immunological scene. While foreign peptides could be assayed by immune reactions, self peptides, as elusive and invisible as they were at the time, were bound to have an immunological role. How self peptides are selected and presented by MHC molecules, and how
Nicholas Fazilleau, Philippe Kourilsky
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Peptide Vaccines and Peptide Libraries
Biological Chemistry, 2001Synthetic immunogens, containing built-in adjuvanticity, B cell, T helper cell and CTL epitopes or mimotopes, are ideal and invaluable tools to study the immune response with respect to antigen processing and presentation. This serves as a basis for the development of complete and minimal vaccines which do not need large carrier proteins, further ...
Karl-Heinz Wiesmüller+2 more
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Unprotected peptides as building blocks for branched peptides and peptide dendrimers
International Journal of Peptide and Protein Research, 1995We describe two new site‐specific ligation methods for preparing branched peptide dendrimers such as multiple antigen peptide (MAP). Both methods are based on the general approach of exploiting the specific reaction between a weak base and an aldehyde under acidic conditions so that unprotected peptides can be used as building blocks.
James P. Tam, Jane C. Spetzler
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Peptide chemistry toolbox – Transforming natural peptides into peptide therapeutics
Bioorganic & Medicinal Chemistry, 2018The development of solid phase peptide synthesis has released tremendous opportunities for using synthetic peptides in medicinal applications. In the last decades, peptide therapeutics became an emerging market in pharmaceutical industry. The need for synthetic strategies in order to improve peptidic properties, such as longer half-life, higher ...
Miloš Erak+3 more
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