Results 111 to 120 of about 5,767,756 (178)
Review of the Composition and Antimicrobial Roles of Extracts of Vine Tea (Ampelopsis grossedentata). [PDF]
Zhang L +10 more
europepmc +1 more source
High‐Content CRISPR Screening: Methods and Applications
High‐content CRISPR screening represents a paradigm shift in functional genomics, moving beyond traditional survival‐based readouts to enable multidimensional mapping of genotype–phenotype relationships. This review systematically outlines the methodological evolution of this approach, detailing advances in perturbation modalities, delivery systems ...
Yike Zhang +6 more
wiley +1 more source
Heterologous expression of NRPS and PKS pathways in Escherichia coli: from bottlenecks to biosynthetic platforms. [PDF]
Göbner L, Gulder TAM, D'Agostino PM.
europepmc +1 more source
Microbial signals from gut and tumor‐resident bacteria, fungi, viruses, and bacteriophages reshape immune and metabolic networks within the tumor microenvironment, thereby influencing cancer progression, treatment response. Therapeutic modulations, including dietary interventions, probiotics, antibiotics, fecal microbiota transplantation, engineered ...
Juan Lu +8 more
wiley +1 more source
Obesity and hypertension co‐exist and share molecular mechanisms in terms of dietary therapy, modulated by food bioactive constituents. ABSTRACT Obesity and hypertension are among the most pressing global public health challenges. They frequently co‐exist, with obesity‐related hypertension accounting for an estimated 75% of the hypertension burden ...
Samuel Oluwasegun Maccarthy +3 more
wiley +1 more source
PHOSPHOLIPID MEMBRANE-PERMEABILITY OF PEPTIDE NUCLEIC-ACID
Phospholipid vesicles (liposomes) as membrane models have been used to study the penetration properties of peptide nucleic acid (PNA), a new DNA analog in which the nucleobases are attached to a pseudo-peptide backbone, The liposomes were characterised ...
MALMSTROM, BG +5 more
core
Comprehensive DIA‐MS Proteomics of Root Basal Nodes Elucidates Mechanisms of Salt Tolerance in Rice
ABSTRACT Soil salinity severely affects rice growth, yield, and quality, posing a global food security challenge. Rice is particularly vulnerable to high salinity, which restricts growth and tolerance to other stresses. To address this, breeding efforts have been made in the past, leading to the generation of multi‐stress‐tolerant rice lines.
Cheol Woo Min +8 more
wiley +1 more source
Nerpa 2: probabilistic linking of biosynthetic gene clusters to nonribosomal peptides. [PDF]
Olkhovskii I +3 more
europepmc +1 more source
RNA‐binding protein RBMS1: A new target for cancer diagnosis and treatment
This schematic illustrates the diverse regulatory roles of RNA‐binding motif single‐stranded interacting protein 1 (RBMS1) across multiple human cancers. In breast cancer, RBMS1 stabilizes B4GALT1 mRNA to promote PD‐L1 glycosylation, modulating tumor immune escape and immunotherapy efficacy.
Xingda Run +7 more
wiley +1 more source
Actinomycin Derivatives: Structural Diversification and Biological Activities. [PDF]
Can Ö, Bedir E.
europepmc +1 more source

