Results 51 to 60 of about 78 (78)
ABSTRACT Cereal crops are fundamental to global food security, but their production is increasingly challenged by rising demand and the unpredictable impacts of climate change. Among the most limiting and interdependent resources sustaining yields are nitrogen and water.
Grace Achieng Ochieng +4 more
wiley +1 more source
Actinomycin Derivatives: Structural Diversification and Biological Activities
Actinomycins are chromopeptide antibiotics exhibiting remarkable structural diversity and broad bioactivity. This review traces their development from naturally occurring D‐, X‐, A‐, G‐, Y‐, and Z‐type analogs to precursor‐directed, synthetic, and semisynthetic derivatives.
Özge Can, Erdal Bedir
wiley +1 more source
The power of many: when genetics met yeasts and high‐throughput
ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley +1 more source
ABSTRACT Radiation therapy (RT) is a mainstay of treatment for a myriad of cancers, often utilized for tumors that are unable to be resected, as well as an adjunct to surgery and chemotherapy. Unfortunately, many cancers are resistant to RT‐induced damage and subsequent cell death.
Joseph Carmicheal +4 more
wiley +1 more source
Thymus vulgaris essential oil (TvEO), largely composed of thymol, showed strong bactericidal activity with Staphylococcus aureus (S. aureus) being most sensitive. TvEO markedly inhibited MRSA biofilm formation and significantly reduced established biofilms. Molecular docking suggests several TvEO components interact with proteins involved in S.
Soumia Dakhouche, Mouna Mnif, Sami Mnif
wiley +1 more source
Development of plant‐derived biomimetic nanoparticles as a novel targeted drug delivery platform
Plant‐derived biomimetic nanoparticles (PD‐BNPs) represent a sustainable and biocompatible nanoplatform for targeted drug delivery. This review highlights their therapeutic potential, engineering strategies, and translational challenges toward precision nanomedicine applications. Abstract Plant‐derived biomimetic nanoparticles (PD‐BNPs) have emerged as
Jihad Hasan +3 more
wiley +1 more source
Applications of Bioinorganic Nano‐Based Delivery Systems—Diagnostics and Therapeutics
ABSTRACT Nanotechnology has emerged as a promising avenue for producing nanomedicines as alternatives to conventional drugs. Many organic nanoparticles, such as liposomes used in formulations like Doxil, Onivyde, and Marqibo, are approved by the Food and Drug Administration (FDA) and instrumental in treating various types of cancers.
Frank Ssengooba +2 more
wiley +1 more source
Spray‐dried xylo‐oligosaccharide‐rich extract derived from olive pit endocarps was assessed for potential cross‐reactivity using in vitro ELISA and in silico approaches. The ELISA tests indicated potential cross‐reactivities with nuts (hazelnut, almond, pistachio, peanut), gluten, and milk in certain batches.
Maame Ekua Manful +4 more
wiley +1 more source
Macrophage: Biological Functions, Diseases, and Therapeutic Targets
Macrophages are sentinel innate immune cells that arise from embryonic precursors and bone marrow monocytes, displaying a functional continuum that transcends the classical M1 (pro‐inflammatory)/M2 (anti‐inflammatory) dichotomy. Under homeostatic conditions, balanced M1/M2 polarization preserves tissue integrity by coordinating immune surveillance ...
Bihang Sun +4 more
wiley +1 more source
Lymphatic Endothelial Cells in Health and Disease
Lymphatic endothelial cells (LECs) are dynamic regulators of tissue homeostasis and disease remodeling. In the healthy state, LECs coordinate interstitial fluid drainage, intestinal lipid transport, and immune trafficking and tolerance. Across disease settings, however, these same programs become maladaptively reprogrammed, contributing to barrier ...
Du Tang +5 more
wiley +1 more source

