Results 51 to 60 of about 78 (78)

Breeding for Resilient Cereals: Integrating Molecular Networks and Trait‐Based Selection to Improve Nitrogen and Water Use Efficiencies

open access: yesPlant, Cell &Environment, Volume 49, Issue 9, Page 6583-6595, September 2026.
ABSTRACT Cereal crops are fundamental to global food security, but their production is increasingly challenged by rising demand and the unpredictable impacts of climate change. Among the most limiting and interdependent resources sustaining yields are nitrogen and water.
Grace Achieng Ochieng   +4 more
wiley   +1 more source

Actinomycin Derivatives: Structural Diversification and Biological Activities

open access: yesChemMedChem, Volume 21, Issue 15, 14 August 2026.
Actinomycins are chromopeptide antibiotics exhibiting remarkable structural diversity and broad bioactivity. This review traces their development from naturally occurring D‐, X‐, A‐, G‐, Y‐, and Z‐type analogs to precursor‐directed, synthetic, and semisynthetic derivatives.
Özge Can, Erdal Bedir
wiley   +1 more source

The power of many: when genetics met yeasts and high‐throughput

open access: yesBiological Reviews, Volume 101, Issue 4, Page 1662-1682, August 2026.
ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley   +1 more source

Overcoming Radiation Resistance: Ferroptosis Induction to Sensitize Solid Tumors to Radiation Therapy

open access: yesCancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Radiation therapy (RT) is a mainstay of treatment for a myriad of cancers, often utilized for tumors that are unable to be resected, as well as an adjunct to surgery and chemotherapy. Unfortunately, many cancers are resistant to RT‐induced damage and subsequent cell death.
Joseph Carmicheal   +4 more
wiley   +1 more source

Phytochemical Composition, In Vitro Antioxidant, Antibacterial, and Antibiofilm Activities of Thymus vulgaris Essential Oil From Tiaret, Algeria

open access: yesChemistry &Biodiversity, Volume 23, Issue 8, August 2026.
Thymus vulgaris essential oil (TvEO), largely composed of thymol, showed strong bactericidal activity with Staphylococcus aureus (S. aureus) being most sensitive. TvEO markedly inhibited MRSA biofilm formation and significantly reduced established biofilms. Molecular docking suggests several TvEO components interact with proteins involved in S.
Soumia Dakhouche, Mouna Mnif, Sami Mnif
wiley   +1 more source

Development of plant‐derived biomimetic nanoparticles as a novel targeted drug delivery platform

open access: yesClinical and Translational Discovery, Volume 6, Issue 4, August 2026.
Plant‐derived biomimetic nanoparticles (PD‐BNPs) represent a sustainable and biocompatible nanoplatform for targeted drug delivery. This review highlights their therapeutic potential, engineering strategies, and translational challenges toward precision nanomedicine applications. Abstract Plant‐derived biomimetic nanoparticles (PD‐BNPs) have emerged as
Jihad Hasan   +3 more
wiley   +1 more source

Applications of Bioinorganic Nano‐Based Delivery Systems—Diagnostics and Therapeutics

open access: yesDrug Development Research, Volume 87, Issue 5, August 2026.
ABSTRACT Nanotechnology has emerged as a promising avenue for producing nanomedicines as alternatives to conventional drugs. Many organic nanoparticles, such as liposomes used in formulations like Doxil, Onivyde, and Marqibo, are approved by the Food and Drug Administration (FDA) and instrumental in treating various types of cancers.
Frank Ssengooba   +2 more
wiley   +1 more source

Assessment of Allergenic Potential for Cross‐Reactivity of Olive (Olea europaea) Pit Xylo‐Oligosaccharide‐Rich Extract With Legislated Allergens in the European Union

open access: yesFood Science &Nutrition, Volume 14, Issue 8, August 2026.
Spray‐dried xylo‐oligosaccharide‐rich extract derived from olive pit endocarps was assessed for potential cross‐reactivity using in vitro ELISA and in silico approaches. The ELISA tests indicated potential cross‐reactivities with nuts (hazelnut, almond, pistachio, peanut), gluten, and milk in certain batches.
Maame Ekua Manful   +4 more
wiley   +1 more source

Macrophage: Biological Functions, Diseases, and Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 8, August 2026.
Macrophages are sentinel innate immune cells that arise from embryonic precursors and bone marrow monocytes, displaying a functional continuum that transcends the classical M1 (pro‐inflammatory)/M2 (anti‐inflammatory) dichotomy. Under homeostatic conditions, balanced M1/M2 polarization preserves tissue integrity by coordinating immune surveillance ...
Bihang Sun   +4 more
wiley   +1 more source

Lymphatic Endothelial Cells in Health and Disease

open access: yesMedComm, Volume 7, Issue 8, August 2026.
Lymphatic endothelial cells (LECs) are dynamic regulators of tissue homeostasis and disease remodeling. In the healthy state, LECs coordinate interstitial fluid drainage, intestinal lipid transport, and immune trafficking and tolerance. Across disease settings, however, these same programs become maladaptively reprogrammed, contributing to barrier ...
Du Tang   +5 more
wiley   +1 more source

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