Results 61 to 70 of about 78 (78)
DNA‐Enzyme Hybrid Nanostructures: Functional Materials to Modulate Enzymatic Activity
Small, Volume 22, Issue 43, 3 August 2026.DNA–enzyme hybrid nanostructures enable precise spatial and stoichiometric control over enzyme organization, offering a powerful platform to modulate catalytic activity. This review critically evaluates key mechanistic hypotheses, including proximity effects, microenvironment changes, confinement, and stabilization, as well as highlighting ...
Manar Elnaggar, Amelie Heuer‐Jungemann
wiley +1 more source
Recent Advances in the Molecular Mechanisms of Bacterial Anti‐Phage Defence Systems
Microbial Biotechnology, Volume 19, Issue 8, August 2026.Panoptes as an example for an antiphage system consists of OptS producing a cyclic dinucleotide that prevents activation of OptE, a transmembrane protein. Phage T4 infection introduces the sponge protein Acb2 that adsorbs the cyclic dinucleotide thus activating OptE which disrupts the cell membrane aborting phage infection.
Harald Brüssow
wiley +1 more source
Identification of drug repurposing candidates for the treatment of polycystic kidney disease
British Journal of Pharmacology, Volume 183, Issue 16, Page 5082-5101, August 2026.Background and Purpose Autosomal dominant polycystic kidney disease (ADPKD) is a leading cause of end‐stage renal disease with limited treatment options. Drug repurposing offers a promising strategy to find effective treatments. Experimental Approach We identified birinapant, bardoxolone methyl and salicylic acid as repurposing candidates for ADPKD and
Alina Meyer +9 more
wiley +1 more source
Beyond Sequence: Posttranslational Remodeling of Antigens in Autoimmunity
Immunological Reviews, Volume 341, Issue 1, August 2026.ABSTRACT Autoimmune responses are often attributed to failed tolerance to self‐proteins, yet protein expression alone cannot explain why certain antigens dominate disease, why autoreactivity emerges under stress, or why specific HLA alleles shape risk.
Cynthiya Shrestha +2 more
wiley +1 more source
Journal of Neurochemistry, Volume 170, Issue 8, August 2026.This work reviews how the metabolic by‐product methylglyoxal may contribute to the development of diabetic peripheral neuropathy (DPN), a common complication of diabetes characterized by nerve damage and chronic pain in the extremities. In diabetes, methylglyoxal levels rise due to increased glucose metabolism and reduced detoxification capacity. While
Gentry Totta‐Griese, Douglas E. Wright
wiley +1 more source
Recombinant Human Collagen in Clinical Medicine
Journal of Cosmetic Dermatology, Volume 25, Issue 8, August 2026.ABSTRACT Background Collagen is the dominant structural protein of vertebrate connective tissues and a central biomaterial in skin, cornea, tendon, cartilage, bone, vessel, oral mucosa, and wound repair. Traditional collagen products have largely been extracted from bovine, porcine, fish, or other animal tissues.
Kyu‐Ho Yi +2 more
wiley +1 more source
Plant, Cell &Environment, Volume 49, Issue 8, Page 5849-5865, August 2026.ABSTRACT In this study, we analyzed a unique Nicotiana tabacum BY‐2 line that was gradually adapted to and subsequently maintained in 190 mM NaCl for over 15 years. Years of continuous high salinity shaped a stable “new homeostasis” in BY‐2 suspension cells. Salt‐adapted cells were smaller and formed tighter clusters. Metabolomics revealed constitutive
Anita Rzadkiewicz +8 more
wiley +1 more source
Some of the next articles are maybe not open access.
Spectral Transition in Bio‐Inspired Self‐Assembled Peptide Nucleic Acid Photonic Crystals
Advanced Materials, 2016Ehud Gazit +2 more
exaly
Peptide Nucleic Acid-Based Biosensors for Cancer Diagnosis
Molecules, 2017Giuseppe Spoto +2 more
exaly