Results 141 to 150 of about 82,531 (244)

Biophysical Characterization and Proteomic Analysis of Small Extracellular Vesicles Derived From Different Neural Cell Lines

Advanced NanoBiomed Research, EarlyView.
This study systematically compares small extracellular vesicles (sEVs) derived from four neural cell lines, revealing how cellular origin shapes vesicle biophysical properties and proteomic cargo. Distinct, lineage‐specific signatures linked to neuronal, astrocytic, and microglial functions are identified, highlighting the importance of cell source ...
Muhammad Waqas Salim, Wei Zhang, Lyndsey E. Collins‐Praino, Andrew Care, Yuling Wang   +4 more
wiley   +1 more source

Harnessing the Reactivity of Sulfinate Salts With Cystine: An Umpolung Approach to Residue‐Specific Peptide Modification

Angewandte Chemie, EarlyView.
While cysteine is widely employed as a nucleophilic handle for peptide modification, the electrophilicity of the oxidized form, cystine, is rarely exploited. This study describes a mild, photochemical coupling of sulfinate salts with peptide disulfides.
Joshua M. Hammond, Esteban Suárez‐Picado, Lena von Sydow, Hanna Bruss, Laurent Knerr, Magnus Johansson, Anaïs Noisier, Lara R. Malins   +7 more
wiley   +2 more sources

Modified Titanium Dental Implants: The Current Progress of Soft‐Tissue Integration Methods

Advanced NanoBiomed Research, EarlyView.
Dental implants are an established solution for tooth loss, yet achieving soft tissue integration (STI) around the transmucosal region remains a challenge. The natural tooth–gingiva interface is poorly replicated on titanium implants. This review explores surface modification strategies, ranging from surface chemistry and topography to biological ...
Daniel De Maria, Amy Gelmi, Peter C. Sherrell, Stefan Di Medio, Nhiem Tran, Kate Fox   +5 more
wiley   +1 more source

Constant trouble with prolines-navigating a global translation dilemma. [PDF]

Nucleic Acids Res
Lassak J, Stritzel J, Schlundt A, Brewer T.   +3 more
europepmc   +1 more source

Atypical Condensation Domains Guide Discovery and Illuminate Biosynthesis of Myxoglucamides Featuring Vinyl‐Substituted, α‐Oxidized γ‐Amino Acids

Angewandte Chemie, EarlyView.
Genome mining of atypical condensation (C) domains leads to the discovery of myxoglucamides, glycolipopeptides featuring an unprecedented vinyl‐substituted, α‐oxidized γ‐amino acid. Biosynthetic studies reveal a discrete C‐domain‐like O‐acyltransferase, a β‐hydroxylation‐dependent chain‐extension checkpoint, and an unusual pathway for γ‐amino acid ...
Tingting Wang, Alexander Popoff, Maja Hunter, Guangzhi Dai, Ronald Garcia, Huixin Xu, Haowen Zhao, Asfandyar Sikandar, Liujie Huo, Rolf Müller, Chengzhang Fu   +10 more
wiley   +2 more sources

Eukaryotic initiation factor eIF3 facilitates loading of eukaryotic release factor eRF1 or suppressor tRNA to the ribosome. [PDF]

Nucleic Acids Res
Shuvalova E, Shuvalov A, Al Sheikh W, Klishin A, Biziaev N, Alkalaeva E.   +5 more
europepmc   +1 more source

A Microscale Platform for the Comprehensive Analysis of Bacterial Translation Initiation. [PDF]

Int J Mol Sci
Vinogradova DS, Kasatsky PS, Spiridonova ZA, Leyva S, Sanchez-Castro A, Peñaranda K, Zegarra V, Soriano P, Paleskava A, Milon P, Konevega AL.   +10 more
europepmc   +1 more source

Mitochondrial translational control in cardiovascular diseases: from mechanisms to therapies. [PDF]

Redox Biol
Deng Y, Guo N, Li D, Wang Z.
europepmc   +1 more source

Single-mRNA imaging and modeling reveal coupled translation initiation and elongation rates. [PDF]

Elife
Lamberti I, Chao JA, Gobet C, Naef F.
europepmc   +1 more source

Pleiotropic roles of elongation factor P in <i>Bacillus subtilis</i> physiology revealed by phenotypic and multi-omics analyses. [PDF]

Microbiol Spectr
Ogura M, Kanesaki Y.
europepmc   +1 more source