Results 141 to 150 of about 159,783 (279)

Nano‐Gs Protein Peptidomimetics: Rational Design of Gα C‐Terminus‐Derived Peptides Mimicking Key Components of Gs‐β2AR Interactions

Angewandte Chemie International Edition, EarlyView.
G protein‐coupled receptors (GPCRs) are major therapeutic targets. Modulating GPCR activity through intracellular sites is evolving. A structure‐ and computation‐assisted approach generated small G protein‐derived peptidomimetics targeting the intracellular binding crevice of the β2 adrenergic receptor mimicking features of the full G protein.
Phuong Thu Tran, Mia Danielsen, Johanna K. S. Tiemann, Passainte Ibrahim, Søren G. F. Rasmussen, Xavier Kubiak, Hossein Batebi, Charlène Gadais, Steven Ballet, Peter W. Hildebrand, Daniel Sejer Pedersen, Jesper Mosolff Mathiesen   +11 more
wiley   +1 more source

Application of the OBIMAP (One-Bead Interchain Multipeptide Assembly Platform) to Long Peptide Synthesis: Liraglutide as a Case Study. [PDF]

ACS Omega
AlShaer D, Al Musaimi O, Williams DR.
europepmc   +1 more source

rRNA expansion segments mediate ribosome dimerization as a conserved stress response. [PDF]

Nucleic Acids Res
Jiang W, Chen C, Wang X, Huang W, Krokowski D, Chen Z, Xie J, Su Z, Hatzoglou M, Taylor DJ, Guo Q.   +10 more
europepmc   +1 more source

Structural basis of TACO1-mediated efficient mitochondrial translation. [PDF]

Nat Commun
Wang S, Brischigliaro M, Zhang Y, Wu C, Zheng W, Barrientos A, Xiong Y.   +6 more
europepmc   +1 more source

Crystals of a large tryptic peptide (fragment A) of elongation factor EF‐Tu from Escherichia coli

FEBS Letters, 1977
Gast, W., Kabsch, W., Wittinghofer, A., Lebermann , R.   +3 more
openaire   +4 more sources

Forcing the Side‐on π‐Coordination of a C≡C Triple Bond to Technetium Using the As,CC,As Alkyne Pincer Ligand 1,2‐Bis(2‐(diisopropylarsaneyl)‐4‐(trifluoromethyl)phenyl)Ethyne

Angewandte Chemie International Edition, EarlyView.
Technetium alkyne complexes have eluded isolation for decades with the only indicators for their existence being the isolation of vinylidene carbenes or their follow‐up reaction products despite plentiful of reports for neighboring elements. Stable, crystalline Tc(III) and Tc(V) alkyne complexes (and their Re analogs) have now been prepared and fully ...
Maximilian Roca Jungfer, Moritz Johannes Ernst, Lukas Eberle, Marius Kesselring, Guilhem Claude, Joachim Ballmann   +5 more
wiley   +1 more source

Constant trouble with prolines-navigating a global translation dilemma. [PDF]

Nucleic Acids Res
Lassak J, Stritzel J, Schlundt A, Brewer T.   +3 more
europepmc   +1 more source

Eukaryotic initiation factor eIF3 facilitates loading of eukaryotic release factor eRF1 or suppressor tRNA to the ribosome. [PDF]

Nucleic Acids Res
Shuvalova E, Shuvalov A, Al Sheikh W, Klishin A, Biziaev N, Alkalaeva E.   +5 more
europepmc   +1 more source

Chitosan/Gelatin Hydrogels With Hydroxyapatite/Silver Nanoparticles: A Dual Antimicrobial and Biocompatible Platform for Bone Regeneration

Journal of Applied Polymer Science, EarlyView.
Chitosan/gelatin hydrogels containing hydroxyapatite or hydroxyapatite/silver nanoparticles were developed and evaluated for bone tissue engineering applications, demonstrating biocompatibility and antimicrobial activity. ABSTRACT Bone tissue engineering demands multifunctional biomaterials capable of promoting regeneration while preventing local ...
Elisabeth Assis Martins Machado, Anne Caroline da Silva Rocha, Lívia Rodrigues de Menezes   +2 more
wiley   +1 more source

Mitochondrial translational control in cardiovascular diseases: from mechanisms to therapies. [PDF]

Redox Biol
Deng Y, Guo N, Li D, Wang Z.
europepmc   +1 more source