Results 171 to 180 of about 355,998 (353)

Quetzal: Comprehensive Peptide Fragmentation Annotation and Visualization

Journal of Proteome Research
Proteomics data-dependent acquisition data sets collected with high-resolution mass-spectrometry (MS) can achieve very high-quality results, but nearly every analysis yields results that are thresholded at some accepted false discovery rate, meaning that a substantial number of results are incorrect. For study conclusions that rely on a small number of
Eric W. Deutsch, Luis Mendoza, Robert L. Moritz   +2 more
openaire   +2 more sources

Effect of PEG crystallization on the self-assembly of PEG/peptide copolymers containing amyloid peptide fragments

, 2008
The effect of poly(ethylene glycol) PEG crystallization on P-sheet fibril formation is studied for a series of three peptide/PEG conjugates containing fragments modified from the amyloid P peptide, specifically KLVFF, FFKLVFF, and AAKLVFF.
Krysmann, M.J., Hamley, I.W., Hamley, Ian W., Krysmann, Marta   +3 more
core   +1 more source

Cross‐Scale Hierarchical Targeted Delivery System Based on Small‐Scale Magnetic Robots

Advanced Robotics Research, EarlyView.
This article reviews a cross‐scale hierarchical targeted delivery system that integrates magnetic continuum robots and magnetic microrobots. By combining rapid long‐range navigation with precise microscale targeting, the system overcomes key limitations of single‐scale approaches.
Junjian Zhou, Zhiqiang Chen, Yuanbiao Ma, Zhiqiang Tang, Qianqian Wang   +4 more
wiley   +1 more source

Anthrax Vaccination, Gulf War Illness, and Human Leukocyte Antigen (HLA)

Vaccines
We report on a highly significant, positive association between anthrax vaccination and occurrence of Gulf War Illness (GWI) in 111 Gulf War veterans (42 with GWI and 69 controls).
Lisa M. James, Adam F. Carpenter, Brian E. Engdahl, Rachel A. Johnson, Scott M. Lewis, Apostolos P. Georgopoulos   +5 more
doaj   +1 more source

Cell Cycle Control of Nuclear Metabolism Couples Phosphatidylinositol Signaling to Histone Methylation

Advanced Science, EarlyView.
Nuclear metabolism oscillates during cell cycle progression. Quantitative chromatome proteomics and imaging reveal phase‐specific dynamics of PIP5K1A and nuclear PIP2, linking phosphatidylinositol metabolism to histone methylation. This work identifies nuclear lipid metabolism as a previously unrecognized regulatory axis coordinating chromatin ...
Antoni Gañez‐Zapater, Savvas Kourtis, Camilla Reiter Elbæk, Lorena Espinar, Carolina Toro‐Márquez, Albert Coll‐Manzano, Alfredo Smiriglia, Laura García‐López, Laura Wiegand, Maria Guirola, Frédéric Fontaine, Andrea Morandi, André C. Müller, Sara Sdelci   +13 more
wiley   +1 more source

A new brain metalloendopeptidase which degrades the Alzheimer ß-amyloid 1-40 peptide producing soluble fragments without neurotoxic effects [PDF]

, 1997
Karine Maria Martins Bezerra Carvalho, Marcelo Santucci França, Gisela Costa Camarão, Andréa Frota Ruchon   +3 more
openalex   +1 more source

Greener Cleavage of Protected Peptide Fragments from Sieber Amide Resin [PDF]

Following the successful introduction of two benign solvents for cleaving protected acid peptide fragments from 2-chlorotrityl chloride (2-CTC) resin, there is a need to green the cleavage process for obtaining protected peptide amide fragments.
Williams DR, Al Musaimi O, Gavva V
core  

In Vivo Quantitation of Collagen/Gelatin Fragments Using HPLC-MS/MS Detection of Peptide Markers

, 2017
Collagen/gelatin fragments are often polydisperse and heterogeneous, making them difficult for quantitation, especially during in vivo circulation. In this study, a new quantitation method was established based on the detection of collagen-specific ...
Zhiguo Su, Zhou, Wan, Zhang, Guifeng, Guifeng Zhang, Hui Yin, Tao Liu, Songshan Tang, Tang, Songshan, Su, Zhiguo, Yin, Hui, Lu Liu, Wan Zhou, Liu, Tao, Liu, Lu   +13 more
core   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

Improving drug-like properties of protein therapeutics through peptide extensions that interact with the Fc fragment of IgG receptor transporter-α (FCGRT; FCRN) [PDF]

, 2012

openalex   +1 more source