Results 191 to 200 of about 355,998 (353)

Activation of cell-penetrating peptide fragments by disulfide formation. [PDF]

open access: yesAmino Acids, 2020
Tooyserkani R   +3 more
europepmc   +1 more source

Statistics of cleavage fragments in random weighted strings

open access: yes, 2005
Kaltenbach H-M, Sudek H, Böcker S, Rahmann S. Statistics of cleavage fragments in random weighted strings. Forschungsberichte der Technischen Fakultät, Abteilung Informationstechnik / Universität Bielefeld.
Sudek, Henner   +3 more
core  

A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase

open access: yesAdvanced Science, EarlyView.
Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol   +18 more
wiley   +1 more source

C-Peptide and Its C-Terminal Fragments Improve Erythrocyte Deformability

open access: yes, 2020
Recommended by Subrata Chakrabarti Aims/hypothesis. Data now indicate that proinsulin C-peptide exerts important physiological effects and shows the characteristics of an endogenous peptide hormone.
Thomas Hach   +5 more
core  

Detection of Listeria monocytogenes with Short Peptide Fragments from Class IIa Bacteriocins as Recognition Elements

open access: yes, 2016
We employed a direct peptide–bacteria binding assay to screen peptide fragments for high and specific binding to Listeria monocytogenes. Peptides were screened from a peptide array library synthesized on cellulose membrane. Twenty four peptide fragments (
Sarfuddin Azmi (1642396)   +4 more
core   +1 more source

GATA4‐Driven Transcription of HtrA1 Promotes Cellular Senescence in Ménière's Disease and Age‐Related Audio‐Vestibular Dysfunction

open access: yesAdvanced Science, EarlyView.
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang   +16 more
wiley   +1 more source

TRMT6‐Mediated m1A Modification of CDK9 mRNA Is a Dual‐Pronged Pathogenic Driver for HBV‐Related Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
TRMT6‐mediated m1A modification in CDK9 mRNA enhances its mRNA stability and translation efficiency, thereby increasing the protein levels of CDK9. Upregulated CDK9 promotes the progression of HCC by elevating the levels of oncogenic factors including p‐STAT3, MCL1, and BCL‐2. On the other hand, CDK9 phosphorylates TARDBP at Ser254 to activate HBV core
Rui Zhang   +12 more
wiley   +1 more source

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