Results 11 to 20 of about 8,430,864 (251)

A novel two-component signal transduction system in propionibacterium acnes and its association with a putative extracellular signalling peptide [PDF]

, 2011
Propionibacterium acnes, a resident micro-organism of human skin, is thought to be involved in the development of inflammatory acne, which is an exclusive human disease affecting more than 80% of the whole population. Quorum sensing is the regulation of
Guan, Shuang
core   +6 more sources

A comprehensive analysis of the importance of translation initiation factors for Haloferax volcanii applying deletion and conditional depletion mutants [PDF]

, 2013
Translation is an important step in gene expression. The initiation of translation is phylogenetically diverse, since currently five different initiation mechanisms are known.
Jörg Soppa, Schmitt, Jessica, Schulz, Sebastian, Näther, Daniela, Katrin Gäbel (484917), Jessica Schmitt (147351), Katrin Gäbel, Gäbel, Katrin, Daniela J Näther, Sebastian Schulz, Soppa, Jörg, Sebastian Schulz (484918), Jörg Soppa (23130), Daniela J. Näther (484919), Jessica Schmitt   +14 more
core   +1 more source

Current Status of Delay in Injectable Therapy among Type 2 Diabetes Mellitus Patients in South Korea: Multicenter Retrospective Study (2015–2021) [PDF]

Endocrinology and Metabolism
Background We aimed to assess the therapeutic inertia associated with injectable therapies and the factors influencing glycemic control following these therapies in patients with type 2 diabetes mellitus (T2DM) in South Korea.
Jong Han Choi, Min Kyong Moon, Hae Jin Kim, Kyung Ae Lee, Hyun Jin Kim, Jung Hae Ko, Jae-Seung Yun, Seung-Hyun Ko, Suk Chon, Nam Hoon Kim   +9 more
doaj   +1 more source

Pinning Down the Transcription: A Role for Peptidyl-Prolyl cis-trans Isomerase Pin1 in Gene Expression

Frontiers in Cell and Developmental Biology, 2020
Pin1 is a peptidyl-prolyl cis-trans isomerase that specifically binds to a phosphorylated serine or threonine residue preceding a proline (pSer/Thr-Pro) motif and catalyzes the cis-trans isomerization of proline imidic peptide bond, resulting in ...
Xiangming Hu, Lin-Feng Chen, Lin-Feng Chen   +2 more
doaj   +1 more source

Translation Initiation Factors eIF3 and HCR1 Control Translation Termination and Stop Codon Read-Through in Yeast Cells [PDF]

, 2013
Translation is divided into initiation, elongation, termination and ribosome recycling. Earlier work implicated several eukaryotic initiation factors (eIFs) in ribosomal recycling in vitro.
Lucie Cuchalová, Lucie Cuchalová (153753), Wagner, Susan, Valasek, Leos S, Cuchalova, Lucie, Petra Beznosková (488568), Susan Wagner, Shoemaker, Christopher J, von der Haar, Tobias, Christopher J Shoemaker, Stanislava Gunišová (153731), Susan Wagner (488569), Beznoskova, Petra, Christopher J. Shoemaker (259606), Leoš Shivaya Valášek (153772), Gunisova, Stanislava, Stanislava Gunišová, Tobias von der Haar, Tobias von der Haar (80575), Petra Beznosková, Leoš Shivaya Valášek   +20 more
core   +2 more sources

Kinetics of initiating polypeptide elongation in an IRES-dependent system

eLife, 2016
The intergenic IRES of Cricket Paralysis Virus (CrPV-IRES) forms a tight complex with 80S ribosomes capable of initiating the cell-free synthesis of complete proteins in the absence of initiation factors. Such synthesis raises the question of what effect
Haibo Zhang, Martin Y Ng, Yuanwei Chen, Barry S Cooperman   +3 more
doaj   +1 more source

The Contribution of Chemoattractant GPCRs, Formylpeptide Receptors, to Inflammation and Cancer

Frontiers in Endocrinology, 2020
A hallmark of inflammatory responses is leukocyte mobilization, which is mediated by pathogen and host released chemotactic factors that activate Gi-protein-coupled seven-transmembrane receptors (GPCRs) on host cell surface. Formylpeptide receptors (FPRs,
Weiwei Liang, Weiwei Liang, Keqiang Chen, Wanghua Gong, Teizo Yoshimura, Yingying Le, Ying Wang, Ji Ming Wang   +7 more
doaj   +1 more source

Mitochondrial polymorphism m.3017C>T of SHLP6 relates to heterothermy

Frontiers in Physiology, 2023
Heterothermic thermoregulation requires intricate regulation of metabolic rate and activation of pro-survival factors. Eliciting these responses and coordinating the necessary energy shifts likely involves retrograde signalling by mitochondrial-derived ...
Sarah V. Emser, Sarah V. Emser, Clemens P. Spielvogel, Eva Millesi, Ralf Steinborn, Ralf Steinborn   +5 more
doaj   +1 more source

2A-induced ribosome stalling [PDF]

, 2014
Originally 2A was characterised in foot-and-mouth disease virus. Site directed mutagenesis identified a C-terminus consensus motif [D(V/I)ExNPGP] and it is proposed that 2A interacts with the exit tunnel of the ribosome in a way that a specific peptide ...
Odon, Valèrie
core   +1 more source

Identification of novel conserved peptide uORF homology groups in Arabidopsis and rice reveals ancient eukaryotic origin of select groups and preferential association with transcription factor-encoding genes

BMC Biology, 2007
Background Upstream open reading frames (uORFs) can mediate translational control over the largest, or major ORF (mORF) in response to starvation, polyamine concentrations, and sucrose concentrations.
Jorgensen Richard A, Hayden Celine A
doaj   +1 more source