Results 231 to 240 of about 725,272 (355)

Stimuli‐Responsive Supramolecular Biomaterials for Cancer Theranostics

Advanced Science, EarlyView.
The ultimate goal of cancer theranostics is to get imaging agents and therapeutic cargo to tumor sites when and where they are required. “Smart” systems should be developed. This review discusses the characteristics of physiological stimuli, types and action modes of external stimuli, construction approaches and working principles, as well as ...
Wenting Hu, Binglin Ye, Guocan Yu, Feihe Huang, Zhengwei Mao   +4 more
wiley   +1 more source

Peptide nucleic acids can form hairpins and bind RNA-binding proteins. [PDF]

PLoS One
Zhong Y, Wilkinson-White L, Zhang E, Mohanty B, Zhang BB, McRae MS, Luo R, Allport TA, Duff AP, Zhao J, El-Kamand S, Du Plessis MD, Cubeddu L, Gamsjaeger R, Ataide SF, Kwan AH.   +15 more
europepmc   +1 more source

Cellular uptake of 2-aminopyridine-modified peptide nucleic acids conjugated with cell-penetrating peptides. [PDF]

Biopolymers, 2022
Brodyagin N, Kataoka Y, Kumpina I, McGee DW, Rozners E.   +4 more
europepmc   +1 more source

Highly efficient strand invasion by peptide nucleic acid bearing optically pure lysine residues in its backbone [PDF]

, 2006
Yoji Yamamoto, Junya Yoshida, Tullia Tedeschi, Roberto Corradini, Stefano Sforza, Makoto Komiyama   +5 more
openalex   +1 more source

AI‐Guided SERS Defines a Pan‐Cancer Diagnostic Biomarker

Advanced Science, EarlyView.
An AI‐enabled SERS platform integrates automated exosome enrichment with molecular fingerprinting to enable accurate early detection and differential diagnosis of ten common cancers. The system identifies exosomal dATP as a universal Raman biomarker, offering a scalable, noninvasive, and clinically translatable approach for precision oncology ...
Cai Zhang, Wen‐Hui Zhao, Duo Zuo, Tianxing Zhou, Wenjing Hou, Lingwei Wang, Shangheng Shi, Yang Yang, Yuanyuan Liu, Shao‐Kai Sun, Li Ren, Zhaoxiang Ye, Dingbin Liu, Dong Li, Xiaoyuan Chen, Jihui Hao   +15 more
wiley   +1 more source

Multicomponent Synthesis of C(8)-Substituted Purine Building Blocks of Peptide Nucleic Acids from Prebiotic Compounds. [PDF]

ChemistryOpen
Mancin E, Capecchi E, Botta L, Bizzarri BM.   +3 more
europepmc   +1 more source

Accurate Identification of Protein Binding Sites for All Drug Modalities Using ALLSites

Advanced Science, EarlyView.
ALLSites is a unified sequence‐based framework for identifying proteome‐wide binding sites across all drug modalities. It integrates a gated convolutional network with a transformer architecture to capture residue interactions directly from the sequence.
Minjie Mou, Mingkun Lu, Zhimeng Zhou, Yanlin Ren, Xinyuan Yu, Ziqi Pan, Yuan Zhou, Hao Yang, Lingyan Zheng, Shukai Gu, Yang Zhang, Wei Hu, Fengcheng Li, Haibin Dai, Feng Zhu   +14 more
wiley   +1 more source

γ Peptide Nucleic Acid-Based miR-122 Inhibition Rescues Vascular Endothelial Dysfunction in Mice Fed a High-Fat Diet

, 2022
Ravinder Reddy Gaddam, Karishma Dhuri, Young‐Rae Kim, Julia S. Jacobs, Vikas Kumar, Qiuxia Li, Kaikobad Irani, Raman Bahal, Ajit Vikram   +8 more
openalex   +1 more source

Multifunctional Gelatin‐Based Smart Films Integrating Thermochromic Encryption, Temperature‐Regulated Photothermal Management, Reprocessability, and Biodegradability for Sustainable Applications

Advanced Science, EarlyView.
Multifunctional gelatin films synergizing thermochromic encryption, self‐regulating photothermal management, and closed‐loop recyclability offer sustainable solutions for intelligent packaging. ABSTRACT Multifunctional gelatin‐based smart films are engineered by incorporating hyperbranched polyglycerol (HBPG) as a plasticizer, dialdehyde β‐cyclodextrin
Yuehong Zhang, Chen Yang, Langlang Dai, Leipeng Liu, Vijay Kumar Thakur   +4 more
wiley   +1 more source

Unveiling the promise of peptide nucleic acids as functional linkers for an RNA imaging platform. [PDF]

RSC Chem Biol
Wierzba AJ, Richards EM, Lennon SR, Batey RT, Palmer AE.   +4 more
europepmc   +1 more source