Optimization of peptide nucleic acid (PNA) oligomer synthesis using Fmoc/acyl-protected monomers
Györgyi Kovács+3 more
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Peptide nucleic acid (PNA) binding-mediated gene regulation [PDF]
Gan Wang, Xiaoxin Xu
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The Neglected Role of GSDMD C‐Terminal in Counteracting Type I Interferon Signaling
The C‐terminal domain of Gasdermin D (GSDMD‐CT) shows functions beyond pyroptosis. GSDMD‐CT negatively regulates IFN‐I signaling during viral infection by triggering autophagic degradation of RIG‐I and TBK1. GSDMD‐CT interacts with retinoic acid‐inducible gene‐I (RIG‐I) and tank‐binding kinase 1 (TBK1), leading to TRIM28‐mediated ubiquitination and ...
Weilv Xu+17 more
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Recognition of mismatched sites in double-stranded DNA by a pair of partially noncomplementary peptide nucleic acids. [PDF]
Shibata M, Shoji O, Aiba Y.
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Stimuli-responsive assembly of bilingual peptide nucleic acids. [PDF]
Argueta-Gonzalez HS+3 more
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Peptide nucleic acids on microarrays and other biosensors [PDF]
Ole Brandt, Jörg D. Hoheisel
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Pulmonary fibrosis (PF) is promoted by NETs that induce fibroblast activation. PEG‐PIm, a polymeric artificial DNase is reported that efficiently degrades NET‐DNA via phosphodiester bond hydrolysis. Inhalation of PEG‐PIm in a mouse PF model prevents fibroblast activation and fibrosis progression, offering a promising therapeutic strategy for NET ...
Yibo Du+7 more
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Peptide nucleic acids can form hairpins and bind RNA-binding proteins. [PDF]
Zhong Y+15 more
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Cellular uptake of 2-aminopyridine-modified peptide nucleic acids conjugated with cell-penetrating peptides. [PDF]
Brodyagin N+4 more
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Intracellular inhibition of hepatitis C virus (HCV) internal ribosomal entry site (IRES)-dependent translation by peptide nucleic acids (PNAs) and locked nucleic acids (LNAs) [PDF]
Christopher J. Nulf
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