Results 231 to 240 of about 719,118 (354)

Polyanion order controls liquid-to-solid phase transition in peptide/nucleic acid co-assembly

, 2022
Christella Gordon-Kim, Allisandra Rha, George Poppitz, Jillian E. Smith‐Carpenter, Regina Luu, Alexis B. Roberson, Russell Conklin, Alexis Blake, David G. Lynn   +8 more
openalex   +1 more source

Retinoic Acid Reprograms Mast Cells Toward a Proinflammatory State to Enhance Antitumor Immunity

Advanced Science, EarlyView.
Proinflammatory mast cells represent an MHC‐IIhigh, cytokine‐producing mast cell subset associated with improved survival and enhanced responses to anti‐PD‐1 therapy. Retinoic acid drives their polarization, enabling antigen uptake and presentation, and T cell recruitment and activation, collectively promoting adaptive anti‐tumor immunity.
Lizao Zhang, Siqi Ren, Yuhui Li, Rongxi Chen, Ling Qiu, Yongmei Tan, Suling Chen, Huiqian Wu, Lianxi Mai, Xiao Tan, Xin Liu, Peisheng Liang, Shijia Kuang, Liansheng Wang, Jingkang Liu, Jintao Li, Yanyan Li, Qiuping Xu, Yongzhi Su, Yuehai Luo, Binyan Wu, Zijing Huang, Haotian Cao, Qunxing Li, Jinsong Li, Tianjun Lan   +25 more
wiley   +1 more source

Anti-Inflammatory Activity of Cell-Penetrating Peptide Nucleic Acids Targeting Indoleamine 2,3-Dioxygenase 1 in IFNγ-Treated Human Keratinocytes. [PDF]

Biomol Ther (Seoul)
Jung D, Ahn S, Park IG, Jeon Y, Lee S, Noh M.   +5 more
europepmc   +1 more source

Primer pairs, PCR conditions, and peptide nucleic acid clamps affect fungal diversity assessment from plant root tissues [PDF]

Chloé Viotti, Michel Chalot, Peter G. Kennedy, François Maillard, Sylvain Santoni, Damien Blaudez, Coralie Bertheau   +6 more
openalex   +1 more source

Integrative Omics Reveal Female‐Specific Benefits of p16+ Cell Clearance in Aging Mice

Advanced Science, EarlyView.
Aging causes accumulation of p16⁺ senescent cells that promote inflammation and dysfunction. Multi‐omics analyses reveal striking sex differences in senescent cell burden and clearance: females accumulate more p16⁺ cells, especially in the liver, and their removal rejuvenates molecular and functional profiles.
Yao Lin, Boshi Wang, Mengling Huang, Justina C. Wolters, Marco Demaria   +4 more
wiley   +1 more source

Recognition of mismatched sites in double-stranded DNA by a pair of partially noncomplementary peptide nucleic acids. [PDF]

Chem Lett
Shibata M, Shoji O, Aiba Y.
europepmc   +1 more source

Highly Sensitive and Quantitative Detection of Mutations in v-Ki-ras2 Kirsten Rat Sarcoma Viral Oncogene by Quantitative Real-Time Polymerase Chain Reaction and Direct Sequencing With Peptide Nucleic Acid-Mediated Polymerase Chain Reaction Clamping [PDF]

, 2012
Arizumi Kikuchi, Takahiro Sawamura, Yuko Wakayama, Hiroya Sakuma, Toshio Katoh, Osami Daimaru, Takeo Nakakita, Shinichi Itoh   +7 more
openalex   +1 more source

An Aptamer‐Based EXACT Anticoagulant as a Sustainable, Animal‐Free Alternative to Unfractionated Heparin

Advanced Science, EarlyView.
By simply conjugating thrombin's active‐site inhibitor, dabigatran, with an exosite inhibitor, aptamer HD1, the resulting EXosite‐ACTive site (EXACT) inhibitors show two orders of magnitude higher potency and selectivity via synergistic binding, while maintaining the aptamer's antidote‐reversible trait, yielding a potential substitute for the animal ...
Haixiang Yu, George Pitoc, Manqi Zhang, Jeffrey Clancy, James Frederiksen, Amy Yan, Samuel Francis, Rebecca Sullenger, Rachel Rempel, Susannah Gammell, Jillian Caiazzi, Bruce A. Sullenger   +11 more
wiley   +1 more source

Peptide nucleic acids can form hairpins and bind RNA-binding proteins. [PDF]

PLoS One
Zhong Y, Wilkinson-White L, Zhang E, Mohanty B, Zhang BB, McRae MS, Luo R, Allport TA, Duff AP, Zhao J, El-Kamand S, Du Plessis MD, Cubeddu L, Gamsjaeger R, Ataide SF, Kwan AH.   +15 more
europepmc   +1 more source

Cellular uptake of 2-aminopyridine-modified peptide nucleic acids conjugated with cell-penetrating peptides. [PDF]

Biopolymers, 2022
Brodyagin N, Kataoka Y, Kumpina I, McGee DW, Rozners E.   +4 more
europepmc   +1 more source