Results 241 to 250 of about 939,420 (304)

A real-world observation of patients with glioblastoma treated with a personalized peptide vaccine. [PDF]

Nat Commun
Latzer P, Zelba H, Battke F, Reinhardt A, Shao B, Bartsch O, Rabsteyn A, Harter J, Schulze M, Okech T, Golf A, Kyzirakos-Feger C, Kayser S, Pieper N, Feldhahn M, Wünsche J, Seitz C, Hadaschik D, Garbe C, Hauser TK, la Fougère C, Biskup D, Brooke D, Parker D, Martens UM, Illerhaus G, Blumenthal DT, Merrell R, Lorenzo LS, Hidvégi M, de Robles P, Kebir S, Li WW, Li VW, Williams M, Miller AM, Kesari S, Castro M, Desjardins A, Ashley DM, Friedman HS, Wen PY, Neil EC, Iwamoto FM, Sipos B, Geletneky K, Zender L, Glas M, Reardon DA, Biskup S.   +49 more
europepmc   +1 more source

Conjugation with S4 protein transduction domain enhances the immunogenicity of the peptide vaccine against breast cancer. [PDF]

Mol Clin Oncol
Moore JA, Ali U, Vungarala S, Young-Seigler A, Tiriveedhi V.   +4 more
europepmc   +1 more source

An Immunoinformatics-Based Multi-Peptide Vaccine Provides Antibody-Mediated Protection Against <i>Acinetobacter baumannii</i> Infection. [PDF]

Vaccines (Basel)
Jeffreys S, Aki J, Tompkins MP, Prather ND, Murthy AK, Chambers JP, Guentzel MN, Hung CY, Arulanandam BP, Yu JJ.   +9 more
europepmc   +1 more source

In silico design and assessment of a multi-epitope peptide vaccine against multidrug-resistant <i>Acinetobacter baumannii</i>. [PDF]

In Silico Pharmacol
Sah SN, Gupta S, Bhardwaj N, Gautam LK, Capalash N, Sharma P.   +5 more
europepmc   +1 more source

Immunogenic Potential of a Multi-Peptide Vaccine Construct Against Uropathogenic Escherichia coli-Associated Urinary Tract Infection. [PDF]

Iran Biomed J
Mirsharifi S, Habibi M, Rahimi T, Foroohi F, Asadi Karam MR.   +4 more
europepmc   +1 more source

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Peptide Vaccines and Peptide Libraries

Biological Chemistry, 2001
Synthetic immunogens, containing built-in adjuvanticity, B cell, T helper cell and CTL epitopes or mimotopes, are ideal and invaluable tools to study the immune response with respect to antigen processing and presentation. This serves as a basis for the development of complete and minimal vaccines which do not need large carrier proteins, further ...
K H, Wiesmüller, B, Fleckenstein, G, Jung   +2 more
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Synthetic peptides as vaccines

Current Opinion in Immunology, 1992
The use of synthetic peptides as an alternative approach to vaccination is currently being pursued. This is particularly true for viral and parasitic diseases in which no vaccines are yet available, most notably the acquired immune deficiency syndrome.
R, Arnon, R J, Horwitz
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Peptides as cancer vaccines

Current Opinion in Pharmacology, 2019
Cancer vaccines based on synthetic peptides are a safe, well-tolerated immunotherapy able to specifically stimulate tumor-reactive T cells. However, their clinical efficacy does not approach that achieved with other immunotherapies such as immune checkpoint blockade.
Calvo Tardon, Marta, Allard, Mathilde Camille, Dutoit Vallotton, Valérie, Dietrich, Pierre-Yves, Walker, Paul Richard   +4 more
openaire   +4 more sources

Synthetic Peptides as Vaccines

Nature, 1987
The economics of vaccines has been a major limitation in the commercial research and development of new approaches. This coupled with the natural scientific desire to simplify and define the composition of effective vaccines argues that the future of vaccines lies in novel approaches that will discover effective and less expensive components. Peptides,
openaire   +2 more sources

Peptide Vaccines for Cancer

Cancer Investigation, 2002
The revelation that immune cytolytic and helper T-cells recognize intracellularly degraded peptides processed via the proteosome apparatus, inserted into the endoplasmic reticulum and transported to the surface for association with major histocompatibility locus (MHC) molecules on specialized antigen-presenting cells has revolutionized the cancer ...
openaire   +2 more sources