Results 241 to 250 of about 1,514,695 (309)

A Physiological Microfluidic Blood–Brain‐Barrier Model for In Vitro Study of Nanoparticle Trafficking and Accumulation

Advanced Healthcare Materials, EarlyView.
A human microfluidic blood‐brain barrier (mBBB) model enables spatially resolved comparison of nanoparticle trafficking. Extracellular vesicles (EVs), liposomes, and nanoplastics exhibit distinct transport and disruption behaviors, revealing that membrane composition and uptake pathways govern BBB interaction.
Bryan B. Nguyen, Neona M. Lowe, Sophia Kellogg, Kuan‐Wei Huang, Hannah O'Toole, Elizabeth J. Hale, Venktesh S. Shirure, Bhupinder S. Shergill, Steven C. George, Randy P. Carney   +9 more
wiley   +1 more source

Physicochemical Characteristics of Amphipathic Peptides and Their Cytotoxic Effects on Cancer and Normal Cell Lines. [PDF]

Int J Mol Sci
Golonka I, Greber KE, Łapińska Z, Wyrzykowski D, Żamojć K, Sikorska E, Kulbacka J, Sawicki W, Musiał W.   +8 more
europepmc   +1 more source

3D Soft Hydrogels Induce Human Mesenchymal Stem Cells “Deep” Quiescence

Advanced Healthcare Materials, EarlyView.
Three‐dimensional soft hydrogels mimicking the bone marrow niche induce deep quiescence in human mesenchymal stem cells. Unlike 2D culture, 3D matrices halt proliferation, regulate cell‐cycle and quiescence markers, and downregulate mTORC1 signaling, preserving stem cell phenotype and therapeutic potential ex vivo.
David Boaventura Gomes, Timo Rademakers, Ana Filipa Henriques Lourenço, Andrea Calore, Clarissa Tomasina, Denis van Beurden, Jinjie Venema, Bryan Chömpff, Hong Liu, Nicole Bouvy, Sandra Camarero‐Espinosa, Lorenzo Moroni   +11 more
wiley   +1 more source

Dimethyl Sulfoxide Enhances HLA Peptide Identification. [PDF]

Proteomes
Lim Kam Sian TCC, Ding Y, Blundell SA, Schittenhelm RB, Faridi P.   +4 more
europepmc   +1 more source

Opinion: Gavage Administration of MXene as a Route‐Specific Alternative to Intravenous Injection into the Bloodstream of Laboratory Animals for Reducing Systemic Nanotoxicity Risks in Immunosuppression and Post‐Transplantation Models with Bile Acid Modification

Advanced Healthcare Materials, EarlyView.
Recent studies reported immunosuppressive properties of specific MXene nanomaterials. Their intravenous injection into the bloodstream of laboratory animals has been a common delivery method to suppress systemic inflammation and prevent transplant rejection.
Alireza Rafieerad, M. Akif Rahman, Ahmad Amiri   +2 more
wiley   +1 more source

Model Peptides Enable Comparisons of Substrate Binding Modes of Hsp70 Molecular Chaperones. [PDF]

Biochemistry
Bhasne K, Dörries L, Maqtedar A, Mager ST, Clerico EM, Gierasch LM.   +5 more
europepmc   +1 more source

Crosslinker nanocarrier-based intratumoral delivery for protein complex mapping in mitochondria of live tumor-bearing mice. [PDF]

Chem Sci
Chen Y, Fu W, Ma B, Li X, Zhou W, Liang Z, Yang K, Zhang L, Zhang Y.   +8 more
europepmc   +1 more source

Recent Advances in Exploring Casein Peptide Regulation of Inflammatory Bowel Disease from an Intestinal Barrier Perspective: Correlations, Mechanisms, Challenges and Solutions. [PDF]

Foods
Dong T, Ye J, Zhang J, Song W, Xia S, Li X, Liu M, Pan D, Wu Z, Tu M.   +9 more
europepmc   +1 more source

Identification of perrhenate-binding peptides by phage display. [PDF]

RSC Adv
Takyi S, Feliciano MAM, Sooriyage DS, Gold B, Walker MC.   +4 more
europepmc   +1 more source

Beef-Derived Peptides Mediated Desensitization of Bitter Taste Receptor T2R14 Through GPCR Kinase 2. [PDF]

Nutrients
Singh N, Drube J, Hoffmann C, Aluko RE, Chelikani P.   +4 more
europepmc   +1 more source