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Inhibition of cellular NEDDylation partially alters the MHC class I immunopeptidome. [PDF]
J ImmunolYari H +5 more
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The Quarterly Journal of Nuclear Medicine and Molecular Imaging, 2020
In recent years, the introduction of theranostic twins for specific diagnosis and treatment in patients with neuroendocrine tumors became a nuclear medicine success story. 64Cu/18F labeled prostate specific membrane antigen (PSMA) for molecular imaging with PET-CT and peptide radioligand therapy with 177Lu labeled PSMA inhibitors will favorably become ...
Siroos, Mirzaei, Rainer W, Lipp
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In recent years, the introduction of theranostic twins for specific diagnosis and treatment in patients with neuroendocrine tumors became a nuclear medicine success story. 64Cu/18F labeled prostate specific membrane antigen (PSMA) for molecular imaging with PET-CT and peptide radioligand therapy with 177Lu labeled PSMA inhibitors will favorably become ...
Siroos, Mirzaei, Rainer W, Lipp
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1995
If we include beta-lactam antibiotics on the grounds that they have the same biosynthetic origin, peptides remain commercially the most important group of pharmaceuticals. However, our increasing knowledge of the genetic and enzymic background to biosynthesis, and of the regulation of metabolite production, will eventually bring a more unified approach
FERREIRA SERGIO H +2 more
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If we include beta-lactam antibiotics on the grounds that they have the same biosynthetic origin, peptides remain commercially the most important group of pharmaceuticals. However, our increasing knowledge of the genetic and enzymic background to biosynthesis, and of the regulation of metabolite production, will eventually bring a more unified approach
FERREIRA SERGIO H +2 more
openaire +5 more sources
Self Peptides and the Peptidic Self
International Reviews of Immunology, 2001Twenty years ago, antigenic and self peptides presented by MHC molecules were absent from the immunological scene. While foreign peptides could be assayed by immune reactions, self peptides, as elusive and invisible as they were at the time, were bound to have an immunological role. How self peptides are selected and presented by MHC molecules, and how
P, Kourilsky, N, Fazilleau
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Peptide Vaccines and Peptide Libraries
Biological Chemistry, 2001Synthetic immunogens, containing built-in adjuvanticity, B cell, T helper cell and CTL epitopes or mimotopes, are ideal and invaluable tools to study the immune response with respect to antigen processing and presentation. This serves as a basis for the development of complete and minimal vaccines which do not need large carrier proteins, further ...
K H, Wiesmüller +2 more
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Journal of Peptide Science, 2005
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Petr, Niederhafner +2 more
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AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Petr, Niederhafner +2 more
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Peptide chemistry toolbox – Transforming natural peptides into peptide therapeutics
Bioorganic & Medicinal Chemistry, 2018The development of solid phase peptide synthesis has released tremendous opportunities for using synthetic peptides in medicinal applications. In the last decades, peptide therapeutics became an emerging market in pharmaceutical industry. The need for synthetic strategies in order to improve peptidic properties, such as longer half-life, higher ...
Miloš, Erak +3 more
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Life Sciences, 1973
Evidence has accumulated that peptides influence behavior by acting on various structures in the brain. Peptides derived from the anterior pituitary (ACTH, growth hormone), the intermediate lobe (α-MSH), and the posterior lobe (vasopressin) of the pituitary have been shown to modulate conditioned behavior (DE WIED, 1969).
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Evidence has accumulated that peptides influence behavior by acting on various structures in the brain. Peptides derived from the anterior pituitary (ACTH, growth hormone), the intermediate lobe (α-MSH), and the posterior lobe (vasopressin) of the pituitary have been shown to modulate conditioned behavior (DE WIED, 1969).
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Peptides: Locally Active Peptides (“Vasoactive Peptides”)
1982Angiotensin may be considered the prototype of the so-called vasoactive peptides inasmuch as its predominant effect is on vascular smooth muscle, which is constricted by both direct and indirect effects of the peptide. However, angiotensin may affect contractility of much extravascular smooth muscle with a predominantly, if not exclusively, stimulatory
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