Results 81 to 90 of about 5,898 (109)

Mechanisms governing bacterial capsular polysaccharide attachment and chain length. [PDF]

Ann N Y Acad Sci
Khadka S, Kinney EL, Ryan BE, Mike LA.
europepmc   +1 more source

"Expanding the Lactococcal Cell Wall Polysaccharide Paradigm: Novel Structures and Metabolic Pathways in the Emerging Dairy Species Pseudolactococcus laudensis and Pseudolactococcus raffinolactis". [PDF]

Microbiologyopen
Soto-Serrano A, Sadovskaya I, Vinogradov E, Li W, Yu JH, White K, van Sinderen D, Krych L, Deptula P, Mahony J.   +9 more
europepmc   +1 more source

Carbon source-dependent transcriptomic regulation and monosaccharide remodeling of exopolysaccharide biosynthesis in Pediococcus pceusentosa LL-07. [PDF]

BMC Microbiol
Lu K, Wang X, Zhou Y, Zhu Q.
europepmc   +1 more source

Exploratory Study of Virulence Factors and Protein-Protein Interaction Networks in Major Oral Pathogens. [PDF]

Contemp Clin Dent
Murmu M, Singh R, Barage S, Kumar AWS.
europepmc   +1 more source

Looking at bacterial cell poles from a liquid-liquid phase separation of intrinsically disordered proteins perspective. [PDF]

Curr Res Struct Biol
Aldadah R, Lekic D, Sabanovic K, Kovalenko B, Adilovic M, Hromic-Jahjefendic A, Uversky VN.   +6 more
europepmc   +1 more source

Positive cooperativity between acceptor and donor sites of the peptidoglycan glycosyltransferase [PDF]

Biochemical Pharmacology, 2015
The glycosyltransferases of family 51 (GT51) catalyze the polymerization of lipid II to form linear glycan chains, which, after cross linking by the transpeptidases, form the net-like peptidoglycan macromolecule. The essential function of the GT makes it an attractive antimicrobial target; therefore a better understanding of its function and its ...
Daniel Bury, Adeline Derouaux, Shrinivas G Dumbre   +2 more
exaly   +4 more sources

Hydrophobic substituents on isatin derivatives enhance their inhibition against bacterial peptidoglycan glycosyltransferase activity

Bioorganic Chemistry, 2020
Moenomycin A, the well-known natural product inhibitor of peptidoglycan glycosyltransferase (PGT), is a large amphiphilic molecule of molecular mass of 1583 g/mol and its bioavailablity as a drug is relatively poor. In searching for small-molecule ligands with high inhibition ability targeting the enzyme, we found that the addition of hydrophobic ...
Yong Wang, Lok-Yan So, Kin-Fai Chan
exaly   +4 more sources

Peptidoglycan glycosyltransferase-ligand binding assay based on tryptophan fluorescence quenching [PDF]

Biochimie, 2018
Peptidoglycan glycosyltransferases (GTase) of family 51 are essential enzymes for the synthesis of the glycan chains of the bacterial cell wall. They are considered potential antibacterial target, but discovery of inhibitors was hampered so far by the lack of efficient and affordable screening assay. Here we used Staphylococcus aureus MtgA to introduce
André Matagne, Shrinivas G Dumbre, Piet Herdewijn   +2 more
exaly   +3 more sources

Some of the next articles are maybe not open access.

Related searches:

Structural details of the glycosyltransferase step of peptidoglycan assembly

Current Opinion in Structural Biology, 2008
The importance of peptidoglycan in forming the basis of the bacterial cell wall has led to many studies investigating its synthesis. The step of cross-linkage via transpeptidation, and its inhibition by penicillins, has been extremely well characterized yet knowledge of the preceding glycosyltransfer reaction remained elusive until recently.
Andrew L Lovering, Natalie C J Strynadka
exaly   +3 more sources