Results 191 to 200 of about 5,729,531 (231)

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Pre-operative circulating tumour DNA in high-risk primary cutaneous melanoma: prospective feasibility in molecular pathology. [PDF]

Acta Oncol
Obinah MPB, Høgdall E, Poulsen TS, Dreisig K, Litman T, Johansen C, Bojesen SE, Hölmich LR.   +7 more
europepmc   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Impact of Greater Surgeon-Anaesthetist Familiarity on Post-Operative Outcomes in Upper Gastrointestinal Cancer Surgery: A 10-Year UK Tertiary Cancer Centre Experience. [PDF]

Cancers (Basel)
Patel NM, Yeung KTD, Patel PH, Doyle J, Beutlhauser T, Williams J, O'Mahony M, Schutzer-Weissmann J, Raobaikady R, Hacking M, Gordon-Williams R, Allum W, Chaudry MA, Bhogal RH, Uren S, Kumar S.   +15 more
europepmc   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Dalla classe alle classi. Andrea Scibetta (eds), Tecniche didattiche per la lingua cinese. Proposte operative per la scuola secondaria di II grado e per l’università. Utet 2024, pp.212.

Lea
Giuseppe Rizzuto
doaj   +1 more source

PREDICT-GBM: A multicenter platform advancing personalized glioblastoma radiotherapy planning. [PDF]

NPJ Digit Med
Zimmer L, Weidner J, Balcerak M, Kofler F, Krupa M, Ezhov I, Cepeda S, Zhang RZ, Lowengrub JS, Menze B, Wiestler B.   +10 more
europepmc   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Robotic-Assisted Spinal Instrumentation from C1 to S1 Experience of a UK Neurosurgical Tertiary Referral Centre. [PDF]

J Clin Med
Baig Mirza A, Rauf W, Muhammad IM, Fayez F, Georgiannakis A, Vastani A, Singh Alg V, Qureshi A, Thakur B, Arvin B, Sadek AR, Sanusi TD.   +11 more
europepmc   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source