Results 101 to 110 of about 2,668,426 (298)

Perceived barriers and facilitators to increasing physical activity among people with musculoskeletal disorders: a qualitative investigation to inform intervention development

, 2014
Steven M McPhail,1,2 Mandy Schippers,1,2 Alison L Marshall,1 Monique Waite,1,2 Pim Kuipers2,3 1Institute of Health and Biomedical Innovation and School of Public Health and Social Work, Queensland University of Technology, 2Centre for Functioning ...
Schippers M, Marshall AL, Kuipers P, McPhail SM, Waite M   +4 more
core  

Perceived Barriers to Integrating Social Science and Conservation

Conservation Biology, 2006
Published by and copyright of Wiley-Blackwell Publishing. The definitive version is available at http://onlinelibrary.wiley.com/doi/10.1111/j.1523-1739.2006.00598.x ...
Helen E, Fox, Caroline, Christian, J Cully, Nordby, Oliver R W, Pergams, Garry D, Peterson, Christopher R, Pyke   +5 more
openaire   +3 more sources

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Perceived Barriers to Healthy Lifestyle Adherence and Associated Factors Among Patients with Type 2 Diabetes Mellitus: Implications for Improved Self-Care [PDF]

Awatif M Alrasheeday,1 Hasna Sumir Alshammari,2,3 Bushra Alshammari,4 Sameer A Alkubati,4,5 Jordan H Llego,4,6 Azizah Dhaher Alshammari,7 Matar Hamed Alshammari,7 Ruqayyah Abdullah Almohammed,7 Saad Mohammed saad Alsheeb,7 Farhan Alshammari8 1Nursing ...
Llego JH, Alsheeb SMS, Alshammari AD, Almohammed RA, Alkubati SA, Alshammari F, Alrasheeday AM, Alshammari HS, Alshammari B, Alshammari MH   +9 more
core  

Barriers to restorative care as perceived by dentists in Nigeria.

Oral health & preventive dentistry, 2016
To identify the barriers to restorative care as perceived by dentists working in urban and semi-urban dental hospitals in Nigeria.The study was cross sectional and the sample consisted of 189 of 280 dentists who consented to, filled out and returned the questionnaire mailed to them.
Temitope Ayodeji, Esan, Elizabeth Obhioneh, Oziegbe   +1 more
openaire   +2 more sources

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Employment after spinal cord injury in the United States: predictors and barriers

Frontiers in Rehabilitation Sciences
IntroductionSpinal cord injury (SCI) is a health condition that severely affects functioning, quality of life, social participation, and employment outcomes.MethodsThis cross-sectional observational study analyzed data from 167 participants with SCI who ...
Georgios Theotokatos, Cristina Sadowsky, Cristina Sadowsky, Shannon Inches, Melissa M. Morrow, Michael Furtado, Lucas R. Burns, Reuben Escorpizo   +7 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source