Results 91 to 100 of about 2,668,426 (298)

Coaching unified sports: associations between perceived athlete improvement, barriers, and coach attitudes across five European countries

Frontiers in Psychology
PurposeThis study aimed to examine how perceived athlete improvement, perceived barriers to implementation, and selected coaching characteristics are associated with coaches’ attitudes toward Unified Sports programs.
Maciej Wilski, Piotr Urbański, Roxana Ossian, Gabriela Papp Eniko, Nina Bracanovic Milovic, Ivan Radovic, Veronica Sedlackova, Eva Gazova, Nadira Sabanovic, Kada Delic Selimovic, Velibor Srdic, Srboljub Vukovic, Damir Ahmic, Vaiva Abramaviciute, Daiva Dabriliene, Ausra Kriskovieciene, Anna Nadolska   +16 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Perceived barriers to pre-exposure prophylaxis use among HIV-negative men who have sex with men in Tijuana, Mexico: A latent class analysis.

PLoS ONE, 2019
BackgroundGiven the slow uptake of PrEP among cisgender men who have sex with men (MSM) in high-income countries, efforts to roll-out PrEP in low- and middle-income countries (LMIC) should address barriers to PrEP use to facilitate its more rapid uptake.
Rudy Patrick, Jennifer Jain, Alicia Harvey-Vera, Shirley J Semple, Gudelia Rangel, Thomas L Patterson, Heather A Pines   +6 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Perceived quality of maternal care and its barriers based on women’s perspective in hospitals of Northwest Ethiopia: a qualitative study

Frontiers in Medicine
BackgroundThe Sustainable Development Goals (SDGs) in health focus on achieving equity to reduce maternal mortality disparities among subpopulations globally.
Maru Mekie, Yismaw Yimam Belachew, Ermias Sisay Chanie, Wubet Alebachew Bayih, Setegn Muche Fenta, Gedefew Abeje Masresha, Wassie Yazie Ferede, Dagne Addisu   +7 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Attitudes, practices and perceived barriers toward implementing non-pharmacological management for rheumatoid arthritis among rheumatologists: an online cross-sectional survey

Introduction Our study aimed to evaluate the integration level of non-pharmacological mana­gement (NPM) for rheumatoid arthritis (RA), analyze attitudes, practices, and perceived barriers towards NPM implementation, and identify factors contributing to ...
Hanan Rkain, Najia Hajjaj-Hassouni, Latifa Tahiri, Nada Benzine, Fatine Kronbi, Fadoua Allali, Redouane Abouqal, Jihane Belayachi, Samya Ez-zaoui   +8 more
core   +1 more source

Predictors of Perceived Barriers to Mammography in Korean Women

Asian Nursing Research, 2008
The purpose of the study was to investigate the effects of cancer fatalism, breast cancer fear, and health motivation on perceived barriers to mammography in Korean women living in the community.The sample for this study was a convenience sample of 138 Korean women.
Jung-Hee Kim, RN, PhD, Oksoo Kim, RN, PhD   +1 more
openaire   +3 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source