Results 71 to 80 of about 137,835 (271)

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Perceived discrimination in medical settings and perceived quality of care: A population-based study in Chicago.

PLoS ONE, 2019
Perceived discrimination in medical settings remains prevalent within the U.S. health care system. However, the details of these experiences and their associations with perceived quality of care are not well understood.
Maureen R Benjamins, Megan Middleton
doaj   +1 more source

Darker Skin Tone Increases Perceived Discrimination among Male but Not Female Caribbean Black Youth

Children, 2017
Background: Among most minority groups, males seem to report higher levels of exposure and vulnerability to racial discrimination. Although darker skin tone may increase exposure to racial discrimination, it is yet unknown whether skin tone similarly ...
Shervin Assari, Cleopatra Howard Caldwell   +1 more
doaj   +1 more source

Pharmacological effects of osimertinib on a chicken chorioallantoic membrane xenograft model with the EGFR exon‐19‐deleted advanced NSCLC mutation

FEBS Open Bio, EarlyView.
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy, Arnaud Vigneron, Xavier Rousset, Jérome Guitton, Emmanuel Grolleau, Margaux Raffin, Julie Balandier, Gaëlle Lescuyer, Mathilde Bardou, Florence Geiguer, Sébastien Couraud, Claire Bardel, Jean Viallet, Nazim Benzerdjeb, Léa Payen   +14 more
wiley   +1 more source

Perceived Discrimination and Subjective Well-being in Chinese Migrant Adolescents: Collective and Personal Self-esteem As Mediators

Frontiers in Psychology, 2017
This study aimed to examine whether collective and personal self-esteem serve as mediators in the relationship between perceived discrimination and subjective well-being among Chinese rural-to-urban migrant adolescents.
Xuji Jia, Xuji Jia, Xia Liu, Baoguo Shi
doaj   +1 more source

A review of artificial intelligence in brachytherapy

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Artificial intelligence (AI) has the potential to revolutionize brachytherapy's clinical workflow. This review comprehensively examines the application of AI, focusing on machine learning and deep learning, in various aspects of brachytherapy.
Jingchu Chen, Richard L. J. Qiu, Tonghe Wang, Shadab Momin, Xiaofeng Yang   +4 more
wiley   +1 more source

Subjective Socioeconomic Status Moderates the Association between Discrimination and Depression in African American Youth

Brain Sciences, 2018
Background: Most of the literature on the association between socioeconomic status (SES) and health is focused on the protective effects of SES. However, a growing literature suggests that high SES may also operate as a vulnerability factor.
Shervin Assari, Brianna Preiser, Maryam Moghani Lankarani, Cleopatra H. Caldwell   +3 more
doaj   +1 more source

Effects of simultaneous multislice acceleration on the stability of radiomics features in parametric maps of IVIM and DKI in uterine cervical cancer

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose The aim of this study was to investigate the influence of the simultaneous multislice acceleration (SMS) technique as well as two‐dimensional (2D) and three‐dimensional (3D) tumor segmentations on radiomics features (RFs) within the parametric maps of cervical cancer, which were computed by intravoxel incoherent motion (IVIM) and ...
Shuangquan Ai, Wei Peng, Rong Hou, Huiting Zhang, Robert Grimm, Zilong Yuan, Yulin Liu   +6 more
wiley   +1 more source

Breakthrough Solution for Antimicrobial Resistance Detection: Surface‐Enhanced Raman Spectroscopy‐based on Artificial Intelligence

Advanced Materials Interfaces, EarlyView., 2023
This review discusses the use of Surface‐Enhanced Raman Spectroscopy (SERS) combined with Artificial Intelligence (AI) for detecting antimicrobial resistance (AMR). Various SERS studies used with AI techniques, including machine learning and deep learning, are analyzed for their advantages and limitations.
Zakarya Al‐Shaebi, Munevver Akdeniz, Awel Olsido Ahmed, Mine Altunbek, Omer Aydin   +4 more
wiley   +1 more source

Combinatorial on/off Model for Olfactory Coding [PDF]

arXiv, 2006
We present a model for olfactory coding based on spatial representation of glomerular responses. In this model distinct odorants activate specific subsets of glomeruli, dependent upon the odorant's chemical identity and concentration. The glomerular response specificities are understood statistically, based on experimentally measured distributions of ...
arxiv